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Over-The-Counter


Affordable Over-the-Counter Medicines Without the Brand-Name Price

Looking for low-cost relief without sacrificing quality? Our over-the-counter selection includes trusted generics that compare to top brands like Mucinex®, Colace®, Robitussin®, Citrucel®, and Phazyme®—all at everyday low prices.

From stool softeners like Docusate Sodium to guaifenesin cough syrups without dextromethorphan, we stock remedies for constipation, cough and cold, indigestion, hemorrhoids, and more. Many of our products are made by trusted manufacturers such as Foster & Thrive®, Rugby®, Major®, and Perrigo®.

  • Constipation Relief: Docusate Sodium, Bisacodyl, PEG 3350
  • Cough & Cold: Robafen DM, Liquid Guaifenesin, Mucus Relief
  • Pain Relief: Capsaicin Cream, Lidocaine Patches, Menthol Rubs
  • Allergies: Diphenhydramine, Cetirizine, Chlorpheniramine
  • Digestive Support: Simethicone, Methylcellulose, Antacids

Need help finding something? Check out our blog or contact us for personalized assistance. We offer fast shipping and discounts on bulk packs for caregivers, clinics, and families stocking up.

What ailment can we help you with today?


⭐ Top Over-the-Counter Deals

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  • Major Fiber Powder Therapy Methylcellulose Orange Flavor - 16oz (Citrucel) Major Fiber Therapy Powder Helps Relieve Stool Irregularity

    Major Fiber Therapy Methylcellulose Powder – 16 oz | Compare to Citrucel

    Major Pharmaceuticals
    $13.99
    Major Fiber Therapy Powder – Methylcellulose 16 oz Orange Flavor | Compare to Citrucel® This is the direct generic replacement for the original Citrucel® Powder with Sugar, which has been permanently discontinued by the manufacturer. It...
  • Rugby Maximum Strength Pain Relieving Cream - 3 oz (Thera-Gesic) Where Can I Buy Rugby Pain Relieving Cream

    Rugby Pain Relieving Cream – 3 oz | Compare to Thera-Gesic

    Rugby Laboratories
    $6.99
    Rugby Pain Relieving Cream – 3 oz | Maximum Strength | Compare to Thera-Gesic Experience fast-acting relief with Rugby Pain Relieving Cream — the trusted generic alternative to Thera-Gesic. This maximum strength formula combines 15% Methyl...
  • Rugby Chest Congestion Relief DM - 60 Tablets (Mucinex DM) Rugby Chest Congestion Relief DM Temporarily relieves coughs that occur with a common cold.

    Rugby Chest Congestion Relief DM - 60 Tablets | Mucinex DM

    Rugby Laboratories
    $8.99
    Rugby Chest Congestion Relief DM – 60 Tablets (Compare to Mucinex DM) Effective daytime relief from cough and chest congestion. Each Rugby Chest Congestion Relief DM tablet contains 400 mg of guaifenesin (expectorant) and 20 mg of dextromethorphan...
  • Rugby Sodium Chloride Hypertonicity Opthalmic Ointment, 5% - 3.5 g | Muro 128 Ointment Rugby Sodium Chloride 5% Ointment Amazon

    Rugby Sodium Chloride Hypertonicity Ophthalmic Ointment 5% | Muro 128

    Rugby Laboratories
    $14.99
    Rugby Sodium Chloride Ophthalmic Ointment 5% – 3.5g Tube | Compare to Muro 128® Need overnight relief from corneal swelling? Rugby Sodium Chloride Ophthalmic Ointment 5% is a sterile, preservative-free eye ointment used for the temporary relief...
  •  Home Aid Pro Comfort Alcohol Pads - 100 Sheets   Home Aid Pro Comfort Alcohol Pads - 100 Sheets Side

    Home Aide Pro Comfort Alcohol Pads - 100 Sheets

    Home Aide
    $3.99
    Pro Comfort Alcohol Prep Pads – Box of 100 | Individually Wrapped Clean Skin. No Fuss. No Burn. Just Comfortably Pro. When it comes to prepping skin, Pro Comfort Alcohol Pads don’t mess around. These 2-ply, individually wrapped wipes are...
  • Rugby Ultra Strength Simethicone Antigas 180mg - 60 Softgels (Phazyme Ultra Strength) New bottle Rugby Simethicone 180 mg - Relief from gas pain, pressure and bloating

    Rugby Ultra Strength Simethicone 180 mg Antigas - 60 Softgels | Phazyme

    Rugby Laboratories
    $6.99
    Rugby Ultra Strength Simethicone Antigas 180 mg – 60 Softgels | Compare to Phazyme® Rugby Ultra Strength Simethicone 180 mg softgels provide fast, maximum-strength relief from gas, pressure, bloating, and abdominal discomfort. As an...
  • Perrigo Cetirizine 10mg - 300 Tablets (Zyrtec) Padagis Cetirizine 10mg - 300 Tablets (Zyrtec)  Benefits

    Perrigo Cetirizine Hydrochloride 10 mg - 300 Tablets | Zyrtec

    Perrigo
    $13.99
    Cetirizine Hydrochloride 10 mg Tablets – 300 Count | Generic Zyrtec® by Perrigo Save on allergy relief with this trusted Zyrtec® generic. Perrigo Cetirizine Hydrochloride 10 mg delivers the same FDA-approved active ingredient as brand-name...
  • Generic Muro 128 Drops | Rugby Sodium Chloride Hypertonicity Ophthalmic Solution 5% Compare Rugby Sodium Chloride Solution vs Muro 128 Solution

    Rugby Sodium Chloride Hypertonicity Ophthalmic Solution 5% | Muro 128

    Rugby Laboratories
    $9.99
    Rugby Sodium Chloride Ophthalmic Solution 5% – 0.5 fl oz | Compare to Muro 128 Looking for a trusted alternative to Muro 128® Drops? Rugby Sodium Chloride Ophthalmic Solution 5% is a hypertonic saline eye drop used to relieve corneal edema...
  • Major Thera-Gel Therapeutic Coal Tar Shampoo - 8.5 fl oz | Neutrogena T-Gel Major Thera-Gel Therapeutic Coal Tar Shampoo - 8.5 fl oz (Neutrogena T-Gel)

    Major Thera-Gel Therapeutic Coal Tar Shampoo - 8.5 fl oz | Neutrogena T-Gel

    Major Pharmaceuticals
    $8.99
    Major Thera-Gel Therapeutic Shampoo – 8.5 fl oz | Coal Tar Dandruff Shampoo Major Thera-Gel Shampoo offers relief for itchy, flaky scalps caused by dandruff, seborrheic dermatitis, or scalp psoriasis. With Coal Tar 0.5% (equivalent to 2% coal tar...
  • Rugby Sodium Chloride Ophthalmic Solution 5% | Muro 128 (3 Pack) Rugby Sodium Chloride Ophthalmic Solution 5% | 3 Pack

    Rugby Sodium Chloride Ophthalmic Solution 5% | Muro 128 (3 Pack)

    Rugby Laboratories
    $19.99
    Rugby Sodium Chloride Ophthalmic Solution 5% – 3 Pack | Compare to Muro 128 Need reliable daytime relief from corneal swelling? This 3-pack of Rugby Sodium Chloride Ophthalmic Solution 5% works the same way as Muro 128®, using a proven...
  • Rugby Meclizine 25 mg - 100 Chewable Tablets (Bonine) Rugby Meclizine 25 mg - 100 Chewable Tablets (Bonine) Benefits

    Rugby Meclizine 25 mg - 100 Chewable Tablets | Bonine

    Rugby Laboratories
    $6.99
    Rugby Meclizine 25 mg Chewable Tablets – 100 Count | Compare to Bonine® Rugby Meclizine 25 mg Chewable Tablets provide reliable relief from motion sickness, nausea, dizziness, and vertigo. Each tablet contains the same active ingredient used in...
  • Home Aide Pure Comfort Alcohol Prep Pads - 100 Packets Home Aide Pure Comfort Alcohol Prep Pads - 100 Packets Top of the Box

    Home Aide Pure Comfort Alcohol Prep Pads - 100 Pads

    Home Aide
    $3.99
    Saturated in 70% isopropyl alcohol. 100 2-ply sheets per box. Individually wrapped in foil packets. For individual, professional and hospital use. Antiseptic for preparation of skin prior to injection. Home Aide Pure Comfort Alcohol...
  • Major Bisacodyl Laxative - 1000 Tablets (Dulcolax) New Bottle Major Bisacodyl 5 mg Stimulant Laxative - 1000 Tablets | Dulcolax

    Major Bisacodyl 5 mg Stimulant Laxative - 1000 Tablets | Dulcolax

    Major Pharmaceuticals
    $11.99
    Major Bisacodyl Stimulant Laxative 5 mg – 1000 Tablets | Compare to  Dulcolax Major Bisacodyl 5 mg tablets offer a fast-acting, affordable solution for occasional constipation relief. As a stimulant laxative, it contains the same active...
  • Rugby High Potency Arthritis Pain Relieving Cream - 2 oz (Zostrix HP) Capsaicin Cream 0.075 Where to Buy

    Rugby Arthritis Pain Relieving Cream - 2 oz | Zostrix HP

    Rugby Laboratories
    $6.99
    Rugby Arthritis Pain Relieving Cream – 0.075% Capsaicin (2 oz) | Compare to Zostrix HP® Looking for a stronger alternative to Zostrix®? Rugby Arthritis Pain Relieving Cream 0.075% delivers the same high-strength active ingredient as Zostrix...
  • Xlear Saline Nasal Spray - 1.5 fl oz Xlear Uses

    Xlear Saline Nasal Spray - 1.5 fl oz

    Xlear
    $9.99
    Experience fast and natural relief from congestion. It alleviates congestion while gently cleansing, soothing, and moisturizing your nasal passages. By washing away pollutants, irritants, and airborne contaminants, it promotes clearer breathing and...
  • Rugby Anti-Itch Lotion 7.5 oz – Compare to Original Sarna Lotion Rugby Anti-Itch Lotion next to Original and New Sarna – Same Ingredients, Better Price

    Rugby Anti-Itch Lotion - 7.5 fl oz | Sarna

    Rugby Laboratories
    $9.39
    Rugby Anti-Itch Lotion – Steroid-Free Relief – 7.5 fl oz | Compare to Sarna® Original Rugby Anti-Itch Lotion is a trusted Sarna generic alternative that delivers the same relief you’ve relied on for decades. With camphor 0.5% and...
  • 5 pack of Major Nasal Decongestant Spray 1 fl oz bottles – generic Afrin pump spray for congestion relief Promotional image of Major Nasal Decongestant Spray 5 Pack – shows free shipping, made in USA, compares to Afrin, and highlights 5 fl oz total for sinus and nasal congestion relief

    Major Nasal Decongestant Spray - 1 fl oz | Compare to Afrin No Drip (5 Pack)

    Major Pharmaceuticals
    $18.95
    Major Nasal Decongestant Spray – 1 fl oz (5 Pack) | Compare to Afrin® No Drip Powerful, non-drowsy nasal relief—without the brand-name markup. This 5-pack of Major 12 Hour Nasal Decongestant Spray contains Oxymetazoline HCl 0.05%, the...
  • Rugby Sodium Chloride Hypertonicity Ophthalmic Ointment 5% - 3.5 g | Muro 128 - 6 Pack rugby sodium chloride ophthalmic ointment 5

    Rugby Sodium Chloride Hypertonicity Ointment 5% | Muro 128 (6 Pack)

    Rugby Laboratories
    $69.96
    Rugby Sodium Chloride Ophthalmic Ointment 5% – 6 Pack (3.5 g Tubes) | Generic for Muro 128 Need reliable overnight relief from corneal swelling? This 6-pack of Rugby Sodium Chloride Ophthalmic Ointment 5% contains the same hypertonic saline...
  • Major Extra Strength Docusate Sodium 250 mg - 100 softgels New Look Major Docusate Sodium 250 mg Bulk Pricing

    Major Docusate Sodium 250 mg - 100 Softgels | Extra Strength Colace

    Major Pharmaceuticals
    $8.99
    Major Extra Strength Docusate Sodium 250 mg – 100 Softgels | Compare to Colace® Major Docusate Sodium 250 mg is a stool softener that provides gentle and reliable relief from occasional constipation. It contains the same active ingredient as...
  • Major Robafen Congestion Formula - 200 mg (Robitussin) Major Robafen Congestion Formula - 200 mg (Robitussin) Drug Facts

    Major Robafen Congestion Formula - 4 fl oz | Robitussin

    Major Pharmaceuticals
    $6.99
    Major Robafen Congestion Formula - 4 fl oz (Discontinued) Although Major Robafen Congestion Formula (Guaifenesin 200 mg) has been discontinued, you can still find effective relief from chest and nasal congestion with our top alternative. We recommend...
  • Rugby Calcium Antacid Regular Strength 150 Chewable Tablets (Generic TUMS) Peppermint Rugby Calcium Antacid Regular Strength 150 Chewable Tablets (Generic TUMS) Peppermint Front Side View

    Rugby Calcium Antacid - Peppermint 150 Chewable Tablets (Tums)

    Rugby Laboratories
    $6.99
    Rugby Calcium Antacid - Peppermint 150 Chewable Tablets (Generic Tums)  Compare to the active ingredient in TUMS REGULAR STRENGTH Calcium Carbonate 500 mg Peppermint flavor  150 chewable tablets  GLUTEN FREE EXPIRATION DATE:...
  • Front view of Foster & Thrive Adult Tussin Guaifenesin 200 mg Expectorant Syrup with no dextromethorphan Front view of a bottle of Foster & Thrive Adult Tussin Guaifenesin 200 mg Expectorant Syrup with no dextromethorphan

    Foster & Thrive Tussin Guaifenesin 200 mg Cough Syrup – 4 fl oz | Compare to Robitussin

    Foster & Thrive
    $9.99
    Foster & Thrive Tussin Guaifenesin 200 mg Cough Syrup – 4 fl oz | Compare to Robitussin Fast, affordable relief for stubborn chest congestion. Each 10 mL dose of Foster & Thrive Tussin delivers Guaifenesin 200 mg—the same expectorant...
  •  Major Banophen Diphenhydramine 50mg - 100 Capsules (Generic Benadryl)  Major Banophen Diphenhydramine 50mg - 100 Capsules (Generic Benadryl)  Drug Facts

    Major Banophen 50 mg - 100 Capsules | Benadryl

    Major Pharmaceuticals
    $6.99
    Major Banophen Diphenhydramine 50 mg – 100 Capsules | Generic Benadryl Alternative Double the dose. Half the price. Major Banophen 50 mg offers the same active ingredient as Benadryl® Allergy—Diphenhydramine HCl 50 mg—in a...
  • Major Cough & Cold - 16 Tablets (Coricidin HBP Cough & Cold) Major Cough & Cold - 16 Tablets Ingredients

    Major Cough & Cold HBP - 16 Tablets | Coricidin HBP Cough & Cold

    Major Pharmaceuticals
    $5.99
    Major Cough & Cold HBP - 16 Tablets - For People with High Blood Pressure Safe Cold Medicine for High Blood Pressure – Compare to Coricidin HBP Major Cough & Cold HBP offers safe, effective relief for cold and cough symptoms—without...
  • Rugby Muscle Rub Cream 3oz Bengay Box Rugby Muscle Rub Cream Amazon

    Rugby Muscle Rub Cream - 3 oz | Bengay

    Rugby Laboratories
    $6.99
    Rugby Muscle Rub Cream – 3 oz | Compare to Bengay Rugby Muscle Rub Cream (3 oz) is a greaseless, fast-absorbing topical analgesic that provides powerful relief from muscle aches, arthritis pain, sprains, and backaches. Each tube contains 10%...
  • Major Extra Strength Docusate Sodium 250 mg - 1000 Softgels (Colace) Major Docusate Sodium 250 mg Bulk Pricing

    Major Docusate Sodium 250 mg - 1000 Softgels | Extra Strength Colace

    Major Pharmaceuticals
    $48.99
    Major Extra Strength Docusate Sodium 250 mg – 1000 Softgels | Compare to Colace® This bulk bottle of Major Docusate Sodium 250 mg contains 1000 softgels, providing the ultimate value for long-term use. As a trusted stool softener, it contains...
  • Major Mintox Plus Tabs - 100 Tablets (Maalox Plus) Mintox Plus Drug Facts Label – Active ingredients and dosage instructions for Major Mintox chewable tablets

    Major Mintox Plus Tabs Antacid Anti-Gas 100 Tablets | Maalox Plus Lemon Mint Flavor

    Major Pharmaceuticals
    $9.95
    Mintox Plus Tabs – 100 Chewable Tablets | Lemon Mint Flavor | Major Brand Quick relief from heartburn, indigestion, and gas—without paying for a brand name. Major Mintox Plus combines three proven ingredients—Aluminum Hydroxide,...
  • Major B-Complex with B-12 Vitamins - 100 Tablets Rugby Vitamin B Complex with B-12 Vitamins Ingredients

    Rugby Vitamin B Complex with B-12 Vitamins - 100 Tablets

    Rugby Laboratories
    $6.99
    Rugby Vitamin B Complex with B-12 Vitamins - 100 Tablets Support your energy, brain function, and overall wellness with Rugby Vitamin B Complex with B-12 Vitamins, a trusted daily supplement that helps convert food into fuel and supports your nervous...
  • Rugby Dextromethorphan HBr USP 15 mg - 20 Softgels Rugby Dextromethorphan HBr USP 15 mg - 20 Softgels - Robitussin CoughGels

    Rugby Dextromethorphan HBr 15 mg - 20 Softgels | Robitussin CoughGels

    Rugby Laboratories
    $7.99
    Rugby Dextromethorphan HBr 15 mg Softgels – 20 Count | Compare to Robitussin® CoughGels Rugby Dextromethorphan HBr 15 mg Softgels provide fast, non-sedating cough suppression to help you get through the day—or sleep through the...
  • Rugby Senna Leaf Extract Syrup 176mg/5mL Dietary Supplement - 8 Fl Oz Rugby Senna Leaf Extract Syrup 176mg/5mL Dietary Supplement - 8 Fl Oz is chocolate flavored

    Rugby Senna Syrup 8 fl oz – 176 mg/5 mL for Constipation Relief

    Rugby Laboratories
    $12.95
    Rugby Senna Syrup – 8 fl oz | Senna Leaf Extract 176 mg/5 mL | Chocolate Flavor Rugby Senna Syrup provides effective overnight relief from occasional constipation. Each teaspoon contains 176 mg of senna leaf extract (as sennosides), a stimulant...
  • Major Calamine Lotion 6 oz bottle – OTC treatment for poison ivy, oak, heat rash, and itchy skin Calamine Lotion Drug Facts – Active ingredients Calamine 8% and Zinc Oxide 8% for poison ivy, heat rash, and bug bite relief

    Major Calamine Lotion - 6 fl oz | Caladryl

    Major Pharmaceuticals
    $7.49
    Calamine Lotion for Poison Ivy, Oak & Heat Rash – Major Brand 6 fl oz OTC Trusted relief for poison ivy, bug bites, rashes, and itchy skin—without paying Caladryl® prices. Major Calamine Lotion is a pharmacist-recommended,...
  • Major Triple Antibiotic Ointment (Generic Neosporin) Major Triple Antibiotic Ointment (Generic Neosporin)  Back Side

    Major Triple Antibiotic Ointment 1 oz – Compare to Neosporin®

    Major Pharmaceuticals
    $6.79
    Major Triple Antibiotic Ointment – 1 oz | Generic Neosporin® for Cuts, Scrapes & Burns Generic Neosporin® at a better price—same ingredients, same protection. This over-the-counter triple antibiotic ointment contains the same...
  • Major Docusate Calcium Stool Softener 240 mg - 1000 Softgels (Surfak) Major Docusate Calcium Stool Softener 240 mg - 1000 Softgels (Surfak) Drug Facts  Label - Side View

    Major Docusate Calcium Stool Softener 240 mg - 1000 Softgels | Surfak

    Major Pharmaceuticals
    $49.99
    For relief of occasional constipation (irregularity). This product generally produces a bowel movement within 12 to 72 hours. Major Docusate Calcium Stool Softener 240 mg - 1000 Softgels | Surfak Compare to the active ingredient in Surfak Laxative...
  • Rugby Urea 20 Cream - 3 oz Urea Cream 20 vs 40

    Rugby Urea 20 Intensive Hydrating Cream - 3 oz

    Rugby Laboratories
    $11.99
    Rugby Urea 20 Cream – 3 oz | Hydrating Urea 20% Moisturizer for Dry Skin Rugby Urea 20 Cream combines hydration and gentle exfoliation to relieve dry, rough, or callused skin. With 20% urea, it helps remove dead skin cells and replenish lost...
  • Rugby Capsaicin Cream 0.025% generic Zostrix alternative for nerve and arthritis pain Rugby Capsaicin Cream Price Comparison – Save vs Amazon and Walmart on 2 oz Single Tube

    Rugby Capsaicin Cream 0.025% - 2 oz | Zostrix

    Rugby Laboratories
    $6.99
    Rugby Capsaicin Cream 0.025% – 2 oz | Compare to Zostrix® Zostrix vs Rugby Capsaicin Cream is a common search for affordable topical pain relief. Rugby Capsaicin Cream 0.025% uses the same active ingredient as Zostrix® (capsaicin 0.025%) to...
  • Rugby Benzoyl Peroxide Wash 10% - 5 fl oz Rugby Benzoyl Peroxide Wash 10% - 5 fl oz - Clean Acne Free Skin

    Rugby Benzoyl Peroxide Wash 10% - 5 fl oz

    Rugby Laboratories
    $9.99
    Rugby Benzoyl Peroxide Wash 10% - 5 fl oz Helps to keep skin clear  Helps to dry oily skin Helps to clear acne pimples 5 fl oz  Expiration Date: 12-2026 Ingredients Active Ingredient: Benzoyl Peroxide USP 10% - Acne Medication Inactive...
  • Major Robafen DM Cough Raspberry Cough Syrup - 24 Fl Oz - Savings Pack Major Robafen DM - 24 Fl Oz - 3 Pack

    Major Robafen DM Cough Syrup – 8 fl oz | Compare to Robitussin DM (3 Pack)

    Major Pharmaceuticals
    $20.99
    Major Robafen DM Cough Syrup – 3 Pack (24 fl oz) | Compare to Robitussin DM (3 Pack) Triple the size. Triple the value. This 3-pack of Major Robafen DM delivers a full 24 fl oz of cough and chest congestion relief—at a lower price than a...
  •  Major FeroSul 325 mg Ferrous Sulfate Iron Supplement - 100 Tablets | Feosol Major Ferosul 325 mg Iron Supplement - 100 Tablets - Label

    Major FeroSul Ferrous Sulfate 325 mg - 100 Tablets | Feosol

    Major Pharmaceuticals
    $5.99
    Major FeroSul Ferrous Sulfate 325 mg – 100 Tablets | Compare to Feosol® Major FeroSul Ferrous Sulfate is a trusted iron supplement designed to help prevent and treat iron deficiency anemia. Each specialty-coated tablet delivers 65 mg of...

Over-the-counter (OTC) medications are non-prescription drugs that can be purchased without a prescription. These medications are intended to provide relief from common ailments and mild health conditions.