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Laxatives & Constipation


Effective Laxatives and Constipation Relief Without the High Price

Shop a wide range of over-the-counter laxatives, stool softeners, and fiber supplements designed to relieve occasional or chronic constipation—without the markup you’ll find at big chain pharmacies.

Whether you need gentle overnight relief, bulk-forming fiber for daily support, or a fast-acting stimulant formula, we offer trusted generics that compare to brands like Dulcolax®, MiraLAX®, Colace®, and Citrucel®.

Our constipation relief products are ideal for seniors, post-surgery recovery, travel-related changes, and those on medications that may slow digestion. All items ship fast and qualify for bulk savings on multi-packs.

Common categories include: stimulant laxatives, stool softeners, osmotic laxatives, and fiber therapy powders.

Need help choosing the right option? Our support team is available to answer your questions.


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  • Major Docusate Sodium 250 mg - 1000 Softgels (Extra Strength Colace) - New Bottle Major Docusate Sodium 250 mg - 1000 Softgels (Extra Strength Colace) - Ingredients, Uses, Directions

    Major Docusate Sodium 250 mg - 1000 Softgels | Extra Strength Colace

    Major Pharmaceuticals
    $51.99
    Major Extra Strength Docusate Sodium 250 mg – 1000 Softgels | Compare to Colace® Clinic Size: Ultimate Value for Long-Term Relief Major Extra Strength Docusate Sodium 250 mg (1000 Softgels) offers...
  • Rugby Senna Syrup - 8 fl oz | Senna Leaf Extract 176 mg / 5 mL Rugby Senna Syrup - Senna Leaf Extract 176mg / 5mL Dietary Supplement - 8 fl oz - Supplement Facts

    Rugby Senna Syrup - 8 fl oz | Senna Leaf Extract 176 mg / 5 mL

    Rugby Laboratories
    $13.99
    Rugby Senna Syrup 176 mg per 5 mL – 8 fl oz (Chocolate Flavor) Gentle Overnight Relief from Occasional Constipation Rugby Senna Syrup provides effective, gentle relief from occasional constipation...
  • Rugby Docusate Sodium Liquid 50 mg/5 ml Stool Softener Cherry - 16 Fl Oz Rugby Docusate Sodium Liquid 50 mg/5 ml Stool Softener Cherry - 16 Fl Oz Drug Facts

    Rugby Docusate Sodium Liquid 50 mg / 5 mL Stool Softener - 16 fl oz | Colace Liquid

    Rugby Laboratories
    $21.99
    Rugby Docusate Sodium Liquid 50 mg/5 mL (16 fl oz) | Compare to Liquid Colace® Gentle, Dependable Relief for Occasional Constipation in an Easy-to-Take Liquid Relieve occasional constipation gently...
  • Rugby Senexon - S - 100 Tablets (Generic Senokot-S) Bottle Rugby Senexon - S - 100 Tablets (Generic Senokot-S) Bottle Drug Facts

    Rugby Senexon-S Docusate Sodium 50 mg / Sennosides 8.6 mg - 100 Tablets | Senokot-S

    Rugby Laboratories
    $9.99
    Rugby Senexon-S Tablets (100 Count) | Compare to Senokot-S® Fast, Dual-Action Relief for Occasional Constipation Rugby Senexon-S provides effective, overnight relief from occasional constipation...
  • Major Docusate Sodium 100 mg - 100 Softgels (Colace Regular Strength) Bottle Major Docusate Sodium 100 mg - 100 Softgels (Colace Regular Strength) Bottle Drug Facts

    Major Docusate Sodium 100 mg - 100 Softgels | Colace

    Major Pharmaceuticals
    $10.99
    Major Docusate Sodium 100 mg Softgels – 100 Count | Compare to Active Ingredient in Colace® Regular Strength Gentle, Predictable Relief for Occasional Constipation Experience comfortable, strain-free...
  • Rugby PEG Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz (MiraLAX) Bottle of Rugby PEG 3350 osmotic laxative on a bathroom counter next to a large green fern and a sink faucet.

    Rugby PEG Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Miralax

    Rugby Laboratories
    $23.99
    Rugby PEG 3350 Polyethylene Glycol 3350 Powder – 17.9 oz (30 Doses) | Compare to MiraLAX® Effective, Low-Cost Relief for Occasional Constipation Rugby PEG 3350 Powder is a trusted, unflavored osmotic...
  • GoodSense ClearLax 17.9 oz 2 pack - 60 doses – polyethylene glycol 3350 osmotic laxative GoodSense ClearLax - generic Miralax that costs less with free shipping

    GoodSense ClearLax Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Miralax (2 Pack)

    GoodSense
    $34.99
    GoodSense ClearLax Polyethylene Glycol 3350 Powder – 17.9 oz (2 Pack) | Compare to MiraLAX® Stock Up & Save: 60 Doses of Gentle Constipation Relief GoodSense® ClearLax® (2-Pack) provides effective,...
  • GoodSense ClearLax 17.9 oz front label view – polyethylene glycol 3350 osmotic laxative Bottle of GoodSense ClearLax on a bathroom counter, next to a glass of water, folded towels, and a sink.

    GoodSense ClearLax Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Miralax

    GoodSense
    $19.99
    GoodSense ClearLax Polyethylene Glycol 3350 Powder – 17.9 oz (30 Doses) | Compare to MiraLAX® Gentle, Predictable Relief for Occasional Constipation GoodSense® ClearLax® provides effective, gentle...
  • Foster & Thrive Epsom Salt Magnesium Sulfate Saline Laxative - 16 oz - xeteor.com Foster & Thrive Epsom Salt bag highlighting fast constipation relief

    Foster & Thrive Epsom Salt Magnesium Sulfate Saline Laxative - 16 oz

    Foster & Thrive
    $10.99
    Foster & Thrive Epsom Salt Magnesium Sulfate Saline Laxative – 16 oz Fast and Effective Relief for Occasional Constipation Foster & Thrive Epsom Salt provides reliable, fast-acting relief from...
  • Geri-Care Polyethylene Glycol 3350 Powder Osmotic Laxative - 8.3 oz | Compare to Miralax Geri-Care Polyethylene Glycol 3350 Powder Osmotic Laxative - 8.3 oz | Compare to Miralax - Full Drug Facts Label

    Geri-Care Polyethylene Glycol 3350 Powder Osmotic Laxative - 8.3 oz | Compare to Miralax

    Geri-Care
    $11.99
    Geri-Care Polyethylene Glycol 3350 Powder Osmotic Laxative – 8.3 oz Gentle, Effective Relief for Occasional Constipation Geri-Care Polyethylene Glycol 3350 Powder offers a gentle, predictable way to...
  • Front view of a white bottle of Geri-Care Stool Softener Docusate Sodium 100 mg containing 250 softgels on a clean white background. Geri-Care Stool Softener 100 mg bottle displayed with loose red liquid softgels in the foreground on a white background.

    Geri-Care Stool Softener Docusate Sodium 100 mg - 200 Softgels | Compare to Colace

    Geri-Care
    $11.99
    Geri-Care Stool Softener – Docusate Sodium 100 mg Softgels – 200 Count | Compare to Active Ingredient in Colace® Regular Strength Gentle, Predictable Relief for Occasional Constipation Experience...
  • Geri-Care Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Compare to Miralax Geri-Care Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Compare to Miralax - Directions, Uses, Ingredients

    Geri-Care Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Compare to Miralax

    Geri-Care
    $20.99
    Geri-Care Polyethylene Glycol 3350 Powder Osmotic Laxative – 17.9 oz | Compare to MiraLAX® Gentle, Effective Relief for Occasional Constipation Geri-Care Polyethylene Glycol 3350 Powder offers a...
  • Health Star Stool Softener Docusate Sodium 250 mg - 100 Softgels Lifestyle graphic featuring a bottle of Health Star Extra Strength Stool Softener on a light wood nightstand next to a clear glass of water and a bowl of almonds, with soft morning sunlight filling the cozy bedroom.

    Health Star Stool Softener - Docusate Sodium 250 mg - 100 Softgels | Extra Strength Colace

    Health Star
    $11.99
    Health Star Extra Strength Stool Softener – Docusate Sodium 250 mg – 100 Softgels | Compare to Colace® Gentle, Effective Relief for Occasional Constipation and Irregularity Relieve digestive...
  • GoodSense ClearLax 8.3 oz front label view – polyethylene glycol 3350 osmotic laxative with orange flavor Comparison chart showing GoodSense ClearLax Orange Flavor vs MiraLAX active ingredient, dosage, and use
    Sale 36%
    Sale 36%

    GoodSense ClearLax Polyethylene Glycol 3350 Powder Osmotic Laxative Orange Flavor - 8.3 oz | Miralax

    GoodSense
    $13.99
    $8.99
    GoodSense ClearLax Polyethylene Glycol 3350 Powder (Orange Flavor) – 8.3 oz | Compare to MiraLAX® Gentle, Orange-Flavored Relief for Occasional Constipation GoodSense® ClearLax® Orange Flavor...
  • Rugby Senna Leaf Extract Syrup 176mg/5mL Dietary Supplement - 8 Fl Oz is chocolate flavored Bottle Rugby Senna Liquid 8 fl oz – 8.8 mg Sennosides Chocolate Laxative

    Rugby Senna Liquid 8 fl oz – 8.8 mg Sennosides Chocolate Laxative

    Rugby Laboratories
    $14.99
    Rugby Senna Liquid 8 fl oz – 8.8 mg Sennosides Chocolate Laxative Rugby Senna Liquid provides gentle, overnight relief from occasional constipation. Each 5 mL teaspoon contains 8.8 mg of sennosides—a...
  • Padagis Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Compare to Miralax Perrigo vs Padagis Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Compare to Miralax

    Perrigo Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Compare to Miralax

    Perrigo
    $25.99
    Perrigo Polyethylene Glycol 3350 Powder Osmotic Laxative – 17.9 oz (30 Doses) | Compare to Active Ingredient in MiraLAX® Gentle, Predictable Relief for Occasional Constipation Find comfortable,...
  • Geri-Care Bisacodyl 5 mg - 100 Tablets | Compare to Dulcolax Geri-Care Bisacodyl 5 mg - 100 Tablets | Compare to Dulcolax - Drug Facts Label

    Geri-Care Bisacodyl 5 mg - 100 Tablets | Compare to Dulcolax

    Geri-Care
    $8.99
    Geri-Care Bisacodyl 5 mg Stimulant Laxative – 100 Tablets | Compare to Dulcolax® Predictable Overnight Relief for Occasional Constipation Get your digestive rhythm back on track with Geri-Care...
  • Health Star Stool Softener Docusate Sodium 250 mg - 100 Softgels - 5 Pack Lifestyle graphic featuring a bottle of Health Star Extra Strength Stool Softener on a light wood nightstand next to a clear glass of water and a bowl of almonds, with soft morning sunlight filling the cozy bedroom.

    Health Star Stool Softener - Docusate Sodium 250 mg - 100 Softgels | Extra Strength Colace (5 Pack)

    Health Star
    $42.95
    Health Star Extra Strength Stool Softener – Docusate Sodium 250 mg – 500 Softgels (5-Pack Bundle) | Compare to Colace® Gentle, Effective Relief for Occasional Constipation and Irregularity Relieve...
  • Health Star Senna-Plus Docusate Sodium 50 mg / Sennosides 8.6 mg - 1000 Tablets | Compare to Senokot-S Close up view of a 1000-count bottle of Health Star Senna-Plus Natural Vegetable Laxative with Stool Softener, with orange tablets spilled in front.

    Health Star Senna-Plus Docusate Sodium 50 mg / Sennosides 8.6 mg - 1000 Tablets | Compare to Senokot-S

    Health Star
    $24.99
    Health Star Senna-Plus Tablets – 1000 Count | Compare to Senokot-S® Dual-Action Overnight Relief: Softens Stool and Gently Stimulates for Comfortable Results Health Star Senna-Plus provides...
  • Major Docusate Sodium 100 mg - 1000 Softgels (Colace Regular Strength) Major Docusate Sodium 100 mg - 1000 Softgels (Colace Regular Strength) Drug Facts

    Major Docusate Sodium 100 mg - 1000 Softgels | Colace

    Major Pharmaceuticals
    $34.99
    Major Docusate Sodium 100 mg – 1000 Tablets | Compare to Colace® Regular Strength Professional Bulk Value: Gentle, Non-Stimulant Relief for Daily Regularity Support your digestive health with Major...
  • Health Star Bisacodyl Suppositories 10 mg, 100 count, fast-acting stimulant laxative compared to the active ingredient in Dulcolax Suppositories (2 Pack) Health Star Bisacodyl Suppositories 10 mg shown in a lifestyle scene for relief of occasional constipation

    Health Star Bisacodyl Suppositories 10 mg - 100 Suppositories | Compare to Dulcolax Suppositories (2 Pack)

    Health Star
    $39.99
    Health Star Bisacodyl Suppositories 10 mg – 2-Pack Bundle (200 Count) | Compare to Dulcolax® Fast, Predictable Relief for Occasional Constipation Find fast, targeted relief from occasional...
  • Health Star Bisacodyl Suppositories 10 mg, 100 count, fast-acting stimulant laxative compared to the active ingredient in Dulcolax Suppositories Health Star Bisacodyl Suppositories 10 mg shown in a lifestyle scene for relief of occasional constipation

    Health Star Bisacodyl Suppositories 10 mg - 100 Suppositories | Compare to Dulcolax Suppositories

    Health Star
    $21.99
    Health Star Bisacodyl Suppositories 10 mg – 100 Count | Compare to Dulcolax® Fast, Predictable Relief for Occasional Constipation Find fast, targeted relief from occasional constipation with Health...
  • Health Star Senna-Plus Docusate Sodium 50 mg / Sennosides 8.6 mg - 1000 Tablets | Compare to Senokot-S (2 Pack) Close up view of a 1000-count bottle of Health Star Senna-Plus Natural Vegetable Laxative with Stool Softener, with orange tablets spilled in front.

    Health Star Senna-Plus Docusate Sodium 50 mg / Sennosides 8.6 mg - 1000 Tablets | Compare to Senokot-S (2 Pack)

    Health Star
    $49.99
    Health Star Senna-Plus Tablets – 2000 Count Total (2-Pack Bundle) | Compare to Senokot-S® Dual-Action Overnight Relief: Softens Stool and Gently Stimulates for Comfortable Results Health Star...