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Laxatives & Constipation


Effective Laxatives and Constipation Relief Without the High Price

Shop a wide range of over-the-counter laxatives, stool softeners, and fiber supplements designed to relieve occasional or chronic constipation—without the markup you’ll find at big chain pharmacies.

Whether you need gentle overnight relief, bulk-forming fiber for daily support, or a fast-acting stimulant formula, we offer trusted generics that compare to brands like Dulcolax®, MiraLAX®, Colace®, and Citrucel®.

Our constipation relief products are ideal for seniors, post-surgery recovery, travel-related changes, and those on medications that may slow digestion. All items ship fast and qualify for bulk savings on multi-packs.

Common categories include: stimulant laxatives, stool softeners, osmotic laxatives, and fiber therapy powders.

Need help choosing the right option? Our support team is available to answer your questions.


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  • Major Bisacodyl Laxative - 1000 Tablets (Dulcolax) New Bottle Major Bisacodyl 5 mg Stimulant Laxative - 1000 Tablets | Dulcolax

    Major Bisacodyl 5 mg Stimulant Laxative - 1000 Tablets | Dulcolax

    Major Pharmaceuticals
    $11.99
    Major Bisacodyl Stimulant Laxative 5 mg – 1000 Tablets | Compare to  Dulcolax Major Bisacodyl 5 mg tablets offer a fast-acting, affordable solution for occasional constipation relief. As a stimulant laxative, it contains the same active...
  • Major Extra Strength Docusate Sodium 250 mg - 100 softgels New Look Major Docusate Sodium 250 mg Bulk Pricing

    Major Docusate Sodium 250 mg - 100 Softgels | Extra Strength Colace

    Major Pharmaceuticals
    $8.99
    Major Extra Strength Docusate Sodium 250 mg – 100 Softgels | Compare to Colace® Major Docusate Sodium 250 mg is a stool softener that provides gentle and reliable relief from occasional constipation. It contains the same active ingredient as...
  • Major Extra Strength Docusate Sodium 250 mg - 1000 Softgels (Colace) Major Docusate Sodium 250 mg Bulk Pricing

    Major Docusate Sodium 250 mg - 1000 Softgels | Extra Strength Colace

    Major Pharmaceuticals
    $48.99
    Major Extra Strength Docusate Sodium 250 mg – 1000 Softgels | Compare to Colace® This bulk bottle of Major Docusate Sodium 250 mg contains 1000 softgels, providing the ultimate value for long-term use. As a trusted stool softener, it contains...
  • Rugby Senna Leaf Extract Syrup 176mg/5mL Dietary Supplement - 8 Fl Oz Rugby Senna Leaf Extract Syrup 176mg/5mL Dietary Supplement - 8 Fl Oz is chocolate flavored

    Rugby Senna Syrup 8 fl oz – 176 mg/5 mL for Constipation Relief

    Rugby Laboratories
    $12.95
    Rugby Senna Syrup – 8 fl oz | Senna Leaf Extract 176 mg/5 mL | Chocolate Flavor Rugby Senna Syrup provides effective overnight relief from occasional constipation. Each teaspoon contains 176 mg of senna leaf extract (as sennosides), a stimulant...
  • Major Docusate Calcium Stool Softener 240 mg - 1000 Softgels (Surfak) Major Docusate Calcium Stool Softener 240 mg - 1000 Softgels (Surfak) Drug Facts  Label - Side View

    Major Docusate Calcium Stool Softener 240 mg - 1000 Softgels | Surfak

    Major Pharmaceuticals
    $49.99
    For relief of occasional constipation (irregularity). This product generally produces a bowel movement within 12 to 72 hours. Major Docusate Calcium Stool Softener 240 mg - 1000 Softgels | Surfak Compare to the active ingredient in Surfak Laxative...
  • Rugby Docusate Sodium Liquid 50 mg/5 ml Stool Softener Cherry - 16 Fl Oz Rugby Docusate Sodium Liquid 50 mg/5 ml Stool Softener Cherry - 16 Fl Oz Drug Facts

    Rugby Docusate Sodium Liquid 50 mg / 5 mL Stool Softener - 16 fl oz | Colace Liquid

    Rugby Laboratories
    $16.99
    Rugby Docusate Sodium Liquid 50 mg/5mL (16 oz) | Compare to Liquid Colace® For those who prefer not to swallow pills, Rugby Docusate Sodium Liquid offers gentle, dependable relief from occasional constipation in an easy-to-take cherry-flavored...
  • Major Bisacodyl Stimulant Laxative 10 mg - 12 Medicated Suppositories (Dulcolax) Major Bisacodyl Stimulant Laxative 10 mg - 12 Medicated Suppositories (Dulcolax) - Drug Facts

    Major Bisacodyl 10 mg - 12 Medicated Suppositories | Dulcolax

    Major Pharmaceuticals
    $8.99
    Major Bisacodyl 10 mg Stimulant Laxative - 12 Medicated Suppositories | Dulcolax Suppositories For the fastest possible relief from occasional constipation, Major Bisacodyl 10 mg Medicated Suppositories are a powerful and effective option. As a stimulant...
  • Major Docusate Sodium 100 mg - 100 Softgels (Colace Regular Strength) Bottle Major Docusate Sodium 100 mg - 100 Softgels (Colace Regular Strength) Bottle Drug Facts

    Major Docusate Sodium 100 mg - 100 Softgels | Colace

    Major Pharmaceuticals
    $6.99
    Major Docusate Sodium 100 mg – 100 Softgels | Colace Regular Strength Stool Softener Major Docusate Sodium 100 mg is a stool softener that provides gentle, reliable relief from occasional constipation. It contains the same active ingredient...
  • Rugby PEG Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz (MiraLAX) Bottle of Rugby PEG 3350 osmotic laxative on a bathroom counter next to a large green fern and a sink faucet.

    Rugby PEG Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Miralax

    Rugby Laboratories
    $19.99
    Rugby PEG 3350 Powder – 17.9 oz (30 Doses) | Compare to Miralax Rugby PEG 3350 Powder is a trusted, unflavored osmotic laxative that provides gentle, effective relief from occasional constipation. It contains the same active ingredient as...
  •  Rugby Enema Saline Laxative 1 Bottle - 4.5 Fl Oz (Fleet)  Rugby Enema Saline Laxative 1 Bottle - 4.5 Fl Oz (Fleet) How-To-Use

    Rugby Enema Saline Laxative 1 Bottle - 4.5 Fl Oz (Fleet)

    Rugby Laboratories
    $6.79
    Rugby Enema Saline Laxative 1 Bottle - 4.5 Fl Oz (Fleet) Compare to the active ingredients of Fleet Saline Enema Ready-to-use For relief of occasional constipation Not made with natural rubber latex  1...
  • Major Bisacodyl Laxative - 1000 Tablets (Dulcolax) New Bottle

    Major Bisacodyl 5 mg Stimulant Laxative - 25 Tablets | Dulcolax

    Major Pharmaceuticals
    $6.99
    Major Bisacodyl 5 mg Stimulant Laxative - 25 Tablets | Dulcolax for Colonoscopy Prep Major Bisacodyl 5 mg is a stimulant laxative that provides fast, effective relief from occasional constipation. This 25-tablet box is a convenient size for travel or for...
  • Rugby Senna Leaf Extract Syrup 176mg/5mL Dietary Supplement - 8 Fl Oz is chocolate flavored Bottle Rugby Senna Leaf Extract Syrup 176mg/5mL Dietary Supplement - 8 Fl Oz is chocolate flavored

    Rugby Senna Liquid 8 fl oz – 8.8 mg Sennosides Chocolate Laxative

    Rugby Laboratories
    $14.99
    Rugby Senna Liquid 8 fl oz – 8.8 mg Sennosides Chocolate Laxative Rugby Senna Liquid provides gentle, overnight relief from occasional constipation. Each 5 mL teaspoon contains 8.8 mg of sennosides—a natural vegetable laxative ingredient...
  • GoodSense ClearLax 17.9 oz 2 pack - 60 doses – polyethylene glycol 3350 osmotic laxative GoodSense ClearLax - generic Miralax that costs less with free shipping

    GoodSense ClearLax Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Miralax (2 Pack)

    GoodSense
    $33.99
    GoodSense® ClearLax Polyethylene Glycol 3350 Powder Osmotic Laxative – 2 Pack (17.9 oz Each) | MiraLAX Compare to MiraLAX® active ingredient. GoodSense® ClearLax® provides gentle, effective relief from occasional constipation with...
  • Major Docusate Sodium 100 mg - 1000 Softgels (Colace Regular Strength) Major Docusate Sodium 100 mg - 1000 Softgels (Colace Regular Strength) Drug Facts

    Major Docusate Sodium 100 mg - 1000 Softgels | Colace

    Major Pharmaceuticals
    $19.99
    Major Docusate Sodium 100 mg - 1000 Softgels | Colace Regular Strength Stool Softener CLEARANCE: Final Bottle – Expires September 2025!This is our very last bottle of the 1000-count, 100 mg strength, and it has been deeply discounted for a quick...
  • GoodSense ClearLax 8.3 oz front label view – polyethylene glycol 3350 osmotic laxative with orange flavor. This is a 2 pack with free shipping. Comparison chart showing GoodSense ClearLax Orange Flavor vs MiraLAX active ingredient, dosage, and use

    GoodSense ClearLax Polyethylene Glycol 3350 Powder Osmotic Laxative Orange Flavor - 8.3 oz | Miralax (2 Pack)

    GoodSense
    $24.99
    GoodSense ClearLax Polyethylene Glycol 3350 Powder Osmotic Laxative Orange Flavor – 8.3 oz (2 Pack) | Compare to MiraLAX® GoodSense ClearLax Polyethylene Glycol 3350 Powder is an orange-flavored, grit-free osmotic laxative designed to relieve...
  • GoodSense ClearLax 8.3 oz front label view – polyethylene glycol 3350 osmotic laxative with orange flavor Comparison chart showing GoodSense ClearLax Orange Flavor vs MiraLAX active ingredient, dosage, and use

    GoodSense ClearLax Polyethylene Glycol 3350 Powder Osmotic Laxative Orange Flavor - 8.3 oz | Miralax

    GoodSense
    $13.95
    GoodSense ClearLax Polyethylene Glycol 3350 Powder Osmotic Laxative Orange Flavor – 8.3 oz | Compare to MiraLAX® GoodSense ClearLax Polyethylene Glycol 3350 Powder is an orange-flavored, grit-free osmotic laxative designed to relieve occasional...
  • GoodSense ClearLax 17.9 oz front label view – polyethylene glycol 3350 osmotic laxative Bottle of GoodSense ClearLax on a bathroom counter, next to a glass of water, folded towels, and a sink.

    GoodSense ClearLax Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Miralax

    GoodSense
    $19.99
    GoodSense® ClearLax Polyethylene Glycol 3350 Powder Osmotic Laxative – 17.9 oz | MiraLAX Compare to MiraLAX® active ingredient. GoodSense® ClearLax® provides effective, gentle relief from occasional constipation with the same active...
  • Laxative Dulcolax® Tablet 100 per Box 5 mg Strength Bisacodyl Box This product is fulfilled by McKesson

    Dulcolax® Tablet 100 per Box 5 mg Strength Bisacodyl Laxative USP

    Dulcolax
    $30.30
    Dulcolax® Laxative Tablets – 100 Count | 5 mg Bisacodyl Dulcolax 5 mg tablets provide fast, predictable relief from occasional constipation. As a stimulant laxative with the active ingredient Bisacodyl, it works by stimulating the intestinal...