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Laxatives & Constipation


Effective Laxatives and Constipation Relief Without the High Price

Shop a wide range of over-the-counter laxatives, stool softeners, and fiber supplements designed to relieve occasional or chronic constipation—without the markup you’ll find at big chain pharmacies.

Whether you need gentle overnight relief, bulk-forming fiber for daily support, or a fast-acting stimulant formula, we offer trusted generics that compare to brands like Dulcolax®, MiraLAX®, Colace®, and Citrucel®.

Our constipation relief products are ideal for seniors, post-surgery recovery, travel-related changes, and those on medications that may slow digestion. All items ship fast and qualify for bulk savings on multi-packs.

Common categories include: stimulant laxatives, stool softeners, osmotic laxatives, and fiber therapy powders.

Need help choosing the right option? Our support team is available to answer your questions.


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  • Major Bisacodyl Laxative - 1000 Tablets (Dulcolax) New Bottle Major Bisacodyl 5 mg Stimulant Laxative - 1000 Tablets | Dulcolax

    Major Bisacodyl 5 mg Stimulant Laxative - 1000 Tablets | Dulcolax

    Major Pharmaceuticals
    $11.99
    Major Bisacodyl Stimulant Laxative 5 mg – 1000 Tablets | Compare to Dulcolax® Predictable Overnight Relief for Occasional Constipation Get your digestive system back on track with Major Bisacodyl 5 mg. As a stimulant laxative, this medication...
  • Major Extra Strength Docusate Sodium 250 mg - 100 softgels New Look 2026 Major Docusate Sodium 250 mg - New Bottle 2026

    Major Docusate Sodium 250 mg - 100 Softgels | Extra Strength Colace

    Major Pharmaceuticals
    $8.99
    Major Extra Strength Docusate Sodium 250 mg – 100 Softgels | Compare to Colace® Gentle, Extra Strength Relief for Occasional Constipation Major Extra Strength Docusate Sodium 250 mg is a stool softener that provides gentle and reliable relief...
  • Major Extra Strength Docusate Sodium 250 mg - 1000 Softgels (Colace) Major Docusate Sodium 250 mg Bulk Pricing

    Major Docusate Sodium 250 mg - 1000 Softgels | Extra Strength Colace

    Major Pharmaceuticals
    $51.99
    Major Extra Strength Docusate Sodium 250 mg – 1000 Softgels | Compare to Colace® Clinic Size: Ultimate Value for Long-Term Relief Major Extra Strength Docusate Sodium 250 mg (1000 Softgels) offers the ultimate value for individuals, caregivers,...
  • Rugby Senna Leaf Extract Syrup 176mg/5mL Dietary Supplement - 8 Fl Oz Rugby Senna Leaf Extract Syrup 176mg/5mL Dietary Supplement - 8 Fl Oz is chocolate flavored

    Rugby Senna Syrup - 8 fl oz | Senna Leaf Extract 176 mg / 5 mL

    Rugby Laboratories
    $13.99
    Rugby Senna Syrup 176 mg per 5 mL – 8 fl oz | Chocolate Flavor Gentle Overnight Relief from Occasional Constipation Rugby Senna Syrup provides effective, gentle relief from occasional constipation using a natural stimulant laxative derived from...
  • Major Docusate Calcium Stool Softener 240 mg - 1000 Softgels (Surfak) Major Docusate Calcium Stool Softener 240 mg - 1000 Softgels (Surfak) Drug Facts  Label - Side View

    Major Docusate Calcium Stool Softener 240 mg - 1000 Softgels | Surfak

    Major Pharmaceuticals
    $49.99
    For relief of occasional constipation (irregularity). This product generally produces a bowel movement within 12 to 72 hours. Major Docusate Calcium Stool Softener 240 mg - 1000 Softgels | Surfak Compare to the active ingredient in Surfak Laxative...
  • Rugby Docusate Sodium Liquid 50 mg/5 ml Stool Softener Cherry - 16 Fl Oz Rugby Docusate Sodium Liquid 50 mg/5 ml Stool Softener Cherry - 16 Fl Oz Drug Facts
    Sale 20%
    Sale 20%

    Rugby Docusate Sodium Liquid 50 mg / 5 mL Stool Softener - 16 fl oz | Colace Liquid

    Rugby Laboratories
    $19.99
    $15.99
    Rugby Docusate Sodium Liquid 50 mg/5mL (16 oz) | Compare to Liquid Colace® Gentle, Dependable Relief for Occasional Constipation in an Easy-to-Take Liquid Rugby Docusate Sodium Liquid offers a convenient solution for individuals who prefer not to...
  • Rugby Senexon - S - 100 Tablets (Generic Senokot-S) Bottle Rugby Senexon - S - 100 Tablets (Generic Senokot-S) Bottle Drug Facts

    Rugby Senexon-S Docusate Sodium 50 mg / Sennosides 8.6 mg - 100 Tablets | Senokot-S

    Rugby Laboratories
    $9.99
    Rugby Senexon-S Tablets (100 Count) | Compare to Senokot-S® Fast, Dual-Action Relief for Occasional Constipation Rugby Senexon-S provides effective, overnight relief from occasional constipation through a dual-action formula. Each tablet combines...
  • Major Docusate Sodium 100 mg - 100 Softgels (Colace Regular Strength) Bottle Major Docusate Sodium 100 mg - 100 Softgels (Colace Regular Strength) Bottle Drug Facts

    Major Docusate Sodium 100 mg - 100 Softgels | Colace

    Major Pharmaceuticals
    $9.99
    Major Docusate Sodium 100 mg – 100 Softgels | Regular Strength Stool Softener Compare to Colace® Gentle, Predictable Relief for Occasional Constipation Experience comfortable, strain-free relief with Major Docusate Sodium 100 mg. As a...
  • Major Bisacodyl Stimulant Laxative 10 mg - 12 Medicated Suppositories (Dulcolax) Major Bisacodyl Stimulant Laxative 10 mg - 12 Medicated Suppositories (Dulcolax) - Drug Facts

    Major Bisacodyl 10 mg - 12 Medicated Suppositories | Dulcolax

    Major Pharmaceuticals
    $9.99
    Major Bisacodyl 10 mg Stimulant Laxative – 12 Medicated Suppositories | Compare to Dulcolax® Fast-Acting, Predictable Relief for Occasional Constipation Get the fastest possible relief from irregularity with Major Bisacodyl 10 mg Medicated...
  • Rugby PEG Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz (MiraLAX) Bottle of Rugby PEG 3350 osmotic laxative on a bathroom counter next to a large green fern and a sink faucet.

    Rugby PEG Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Miralax

    Rugby Laboratories
    $24.99
    Rugby PEG 3350 Polyethylene Glycol 3350 Powder – 17.9 oz (30 Doses) | Compare to MiraLAX® Effective, Low-Cost Relief for Occasional Constipation Rugby PEG 3350 Powder is a trusted, unflavored osmotic laxative that provides gentle, effective...
  • Major DOK Docusate Sodium Stool Softener 100 mg - 100 Crushable Tablets  Bottle Major DOK Docusate Sodium Stool Softener 100 mg - 100 Crushable Tablets  Bottle Drug Facts

    Major DOK Docusate Sodium 100 mg - 100 Crushable Tablets | Compare to Colace

    Major Pharmaceuticals
    $9.99
    Major DOK Docusate Sodium 100 mg – 100 Crushable Tablets | Compare to Colace® Gentle, Reliable Relief for Occasional Constipation in a Convenient Crushable Tablet Major DOK Docusate Sodium is a trusted, gentle stool softener used to relieve...
  • GoodSense ClearLax 17.9 oz 2 pack - 60 doses – polyethylene glycol 3350 osmotic laxative GoodSense ClearLax - generic Miralax that costs less with free shipping

    GoodSense ClearLax Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Miralax (2 Pack)

    GoodSense
    $34.99
    GoodSense ClearLax Polyethylene Glycol 3350 Powder – 17.9 oz (2 Pack) | Compare to MiraLAX® Stock Up & Save: 60 Doses of Gentle Constipation Relief GoodSense® ClearLax® (2-Pack) provides effective, gentle relief from occasional...
  • GoodSense ClearLax 17.9 oz front label view – polyethylene glycol 3350 osmotic laxative Bottle of GoodSense ClearLax on a bathroom counter, next to a glass of water, folded towels, and a sink.

    GoodSense ClearLax Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Miralax

    GoodSense
    $19.99
    GoodSense ClearLax Polyethylene Glycol 3350 Powder – 17.9 oz (30 Doses) | Compare to MiraLAX® Gentle, Predictable Relief for Occasional Constipation GoodSense® ClearLax® provides effective, gentle relief from occasional constipation...
  •  Rugby Enema Saline Laxative 1 Bottle - 4.5 Fl Oz (Fleet)  Rugby Enema Saline Laxative 1 Bottle - 4.5 Fl Oz (Fleet) How-To-Use

    Rugby Enema Saline Laxative 1 Bottle - 4.5 Fl Oz (Fleet)

    Rugby Laboratories
    $6.79
    Rugby Enema Saline Laxative 1 Bottle - 4.5 Fl Oz (Fleet) Compare to the active ingredients of Fleet Saline Enema Ready-to-use For relief of occasional constipation Not made with natural rubber latex  1...
  • Geri-Care Polyethylene Glycol 3350 Powder Osmotic Laxative - 8.3 oz | Compare to Miralax Geri-Care Polyethylene Glycol 3350 Powder Osmotic Laxative - 8.3 oz | Compare to Miralax - Full Drug Facts Label

    Geri-Care Polyethylene Glycol 3350 Powder Osmotic Laxative - 8.3 oz | Compare to Miralax

    Geri-Care
    $10.99
    Geri-Care Polyethylene Glycol 3350 Powder Osmotic Laxative – 8.3 oz Gentle, Effective Relief for Occasional Constipation Geri-Care Polyethylene Glycol 3350 Powder offers a gentle, predictable way to relieve occasional constipation and irregularity...
  • Major Bisacodyl Laxative - 1000 Tablets (Dulcolax) New Bottle

    Major Bisacodyl 5 mg Stimulant Laxative - 25 Tablets | Dulcolax

    Major Pharmaceuticals
    $6.99
    Major Bisacodyl 5 mg Stimulant Laxative – 25 Tablets | Compare to Dulcolax® for Colonoscopy Prep Travel-Sized Predictable Relief: Ideal for Short-Term Needs and Medical Preparation Whether you’re preparing for a medical procedure or...
  • Rugby Senna Leaf Extract Syrup 176mg/5mL Dietary Supplement - 8 Fl Oz is chocolate flavored Bottle Rugby Senna Liquid 8 fl oz – 8.8 mg Sennosides Chocolate Laxative

    Rugby Senna Liquid 8 fl oz – 8.8 mg Sennosides Chocolate Laxative

    Rugby Laboratories
    $14.99
    Rugby Senna Liquid 8 fl oz – 8.8 mg Sennosides Chocolate Laxative Rugby Senna Liquid provides gentle, overnight relief from occasional constipation. Each 5 mL teaspoon contains 8.8 mg of sennosides—a natural vegetable laxative ingredient...
  • Foster & Thrive Epsom Salt Magnesium Sulfate Saline Laxative - 16 oz Foster & Thrive Epsom Salt bag highlighting fast constipation relief

    Foster & Thrive Epsom Salt Magnesium Sulfate Saline Laxative - 16 oz

    Foster & Thrive
    $10.99
    Foster & Thrive Epsom Salt Magnesium Sulfate Saline Laxative – 16 oz Fast and Effective Relief for Occasional Constipation Foster & Thrive Epsom Salt provides reliable, fast-acting relief from occasional constipation and irregularity. Made...
  • Foster & Thrive Gentle Laxative Bisacodyl 10 mg - 8 Suppositories | Compare to Dulcolax Suppositories - 6 Pack Foster & Thrive Gentle Laxative Bisacodyl 10 mg - 8 Suppositories | Compare to Dulcolax Suppositories - 6 Pack Free Shipping

    Foster & Thrive Gentle Laxative Bisacodyl 10 mg - 8 Suppositories | Compare to Dulcolax Suppositories (6 Pack)

    Foster & Thrive
    $19.99
    Foster & Thrive Gentle Laxative Bisacodyl USP 10 mg – 8 Medicated Suppositories (6-Pack) | Compare to Dulcolax® Maximum Bulk Value: Fast-Acting, Predictable Relief in 15–60 Minutes When your schedule is packed, you don't have twelve...
  • Health Star Senna-Plus Docusate Sodium 50 mg / Sennosides 8.6 mg - 1000 Tablets | Compare to Senokot-S Close up view of a 1000-count bottle of Health Star Senna-Plus Natural Vegetable Laxative with Stool Softener, with orange tablets spilled in front.

    Health Star Senna-Plus Docusate Sodium 50 mg / Sennosides 8.6 mg - 1000 Tablets | Compare to Senokot-S

    Health Star
    $24.99
    Health Star Senna-Plus Tablets – 1000 Count | Compare to Senokot-S® Dual-Action Overnight Relief: Softens Stool and Gently Stimulates for Comfortable Results Health Star Senna-Plus provides effective, overnight relief from occasional...
  • Health Star Stool Softener Docusate Sodium 250 mg - 100 Softgels Lifestyle graphic featuring a bottle of Health Star Extra Strength Stool Softener on a light wood nightstand next to a clear glass of water and a bowl of almonds, with soft morning sunlight filling the cozy bedroom.

    Health Star Stool Softener - Docusate Sodium 250 mg - 100 Softgels | Extra Strength Colace

    Health Star
    $10.99
    Health Star Docusate Sodium 250 mg – 100 Softgels | Extra Strength Stool Softener Compare to Colace® Gentle, Effective Relief for Occasional Constipation and Irregularity Relieve digestive discomfort and promote regularity with Health Star...
  • Major Docusate Sodium 100 mg - 1000 Softgels (Colace Regular Strength) Major Docusate Sodium 100 mg - 1000 Softgels (Colace Regular Strength) Drug Facts

    Major Docusate Sodium 100 mg - 1000 Softgels | Colace

    Major Pharmaceuticals
    $34.99
    Major Docusate Sodium 100 mg – 1000 Tablets | Compare to Colace® Regular Strength Professional Bulk Value: Gentle, Non-Stimulant Relief for Daily Regularity Support your digestive health with Major Docusate Sodium 100 mg. Designed to match the...
  • Health Star Senna-Plus Docusate Sodium 50 mg / Sennosides 8.6 mg - 1000 Tablets | Compare to Senokot-S (2 Pack) Close up view of a 1000-count bottle of Health Star Senna-Plus Natural Vegetable Laxative with Stool Softener, with orange tablets spilled in front.

    Health Star Senna-Plus Docusate Sodium 50 mg / Sennosides 8.6 mg - 1000 Tablets | Compare to Senokot-S (2 Pack)

    Health Star
    $49.99
    Health Star Senna-Plus Tablets – 2000 Count Total (2-Pack Bundle) | Compare to Senokot-S® Dual-Action Overnight Relief: Softens Stool and Gently Stimulates for Comfortable Results Health Star Senna-Plus provides effective, overnight relief from...
  • Geri-Care Docusate Sodium Liquid 50 mg / 5 ml Stool Softener Cherry - 16 Fl Oz - 3 Pack Geri-Care Docusate Sodium Liquid 50 mg / 5 ml Stool Softener Cherry - 16 Fl Oz - 3 Pack with Free Shipping

    Geri-Care Docusate Sodium Liquid 50 mg / 5 mL Stool Softener - 16 fl oz | Colace Liquid (3 Pack)

    Geri-Care
    $49.99
    Geri-Care Docusate Sodium 50 mg / 5 mL Stool Softener Liquid – 16 fl oz (3-Pack Bundle) Gentle, Stimulant-Free Relief for Occasional Constipation Stock up and save with the Geri-Care Docusate Sodium Liquid 3-Pack Bundle. This trusted stool softener...
  • Padagis Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Compare to Miralax 238 ml for colonoscopy prep Padagis Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Compare to Miralax

    Perrigo Polyethylene Glycol 3350 Powder Osmotic Laxative - 8.3 oz | Compare to Miralax

    Perrigo
    $16.99
    Perrigo Polyethylene Glycol 3350 Powder Osmotic Laxative – 8.3 oz | Compare to MiraLAX® Gentle, Predictable Relief for Occasional Constipation Find comfortable, effective relief from irregularity with Perrigo Polyethylene Glycol 3350 Powder...
  • Padagis Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Compare to Miralax Perrigo vs Padagis Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Compare to Miralax

    Perrigo Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Compare to Miralax

    Perrigo
    $25.99
    Perrigo Polyethylene Glycol 3350 Powder Osmotic Laxative – 17.9 oz | Compare to MiraLAX® Gentle, Predictable Relief for Occasional Constipation Find comfortable, effective relief from irregularity with Perrigo Polyethylene Glycol 3350 Powder...
  • Foster & Thrive Magnesium Citrate Saline Laxative Cherry Flavor - 10 fl oz Foster & Thrive Magnesium Citrate Saline Laxative Cherry Flavor - 10 fl oz - Drug Facts Label

    Foster & Thrive Magnesium Citrate Saline Laxative Cherry Flavor - 10 fl oz

    Foster & Thrive
    $10.99
    Foster & Thrive Magnesium Citrate Saline Laxative Cherry Flavor – 10 fl oz Fast and Effective Relief for Occasional Constipation Foster & Thrive Magnesium Citrate in a pleasant cherry flavor provides reliable, fast-acting relief from...
  • Foster & Thrive Magnesium Citrate Saline Laxative Lemon Flavor - 10 fl oz Foster & Thrive Magnesium Citrate Saline Laxative Lemon Flavor - 10 fl oz - Drug Facts Label

    Foster & Thrive Magnesium Citrate Saline Laxative Lemon Flavor - 10 fl oz

    Foster & Thrive
    $10.99
    Foster & Thrive Magnesium Citrate Saline Laxative Lemon Flavor – 10 fl oz Fast and Effective Relief for Occasional Constipation Foster & Thrive Magnesium Citrate in a pleasant lemon flavor provides reliable, fast-acting relief from...
  • Geri-Care Stool Softener Docusate Sodium 100 mg - 1000 Softgels | Compare to Colace Geri-Care Stool Softener Docusate Sodium 100 mg - 1000 Softgels | Compare to Colace Drug Facts

    Geri-Care Stool Softener Docusate Sodium 100 mg - 1000 Softgels | Compare to Colace

    Geri-Care
    $25.99
    Geri-Care Stool Softener Docusate Sodium 100 mg – 1000 Softgels | Compare to Colace® Regular Strength Professional Bulk Value: Gentle, Non-Stimulant Relief for Daily Regularity Support your digestive comfort with Geri-Care Stool Softener 100 mg...
  • Geri-Care Bisacodyl 5 mg - 100 Tablets | Compare to Dulcolax Geri-Care Bisacodyl 5 mg - 100 Tablets | Compare to Dulcolax - Drug Facts Label

    Geri-Care Bisacodyl 5 mg - 100 Tablets | Compare to Dulcolax

    Geri-Care
    $6.99
    Geri-Care Bisacodyl 5 mg Stimulant Laxative – 100 Tablets | Compare to Dulcolax® Predictable Overnight Relief for Occasional Constipation Get your digestive rhythm back on track with Geri-Care Bisacodyl. As a powerful stimulant laxative, this...