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Antihistamine Medicine


Antihistamine and allergy medicine includes several types of over-the-counter products for symptoms such as sneezing, runny nose, itchy or watery eyes, and nasal congestion. Xeteor carries oral antihistamines such as cetirizine, loratadine, diphenhydramine, and chlorpheniramine, along with nasal sprays and other allergy and cold-relief options.

Looking for help choosing a product? Explore our guides to Zyrtec Generic Alternatives, Claritin Generic Alternatives, Benadryl Generic Alternatives, Afrin Generic Alternatives, and Coricidin HBP Generic Alternatives. You can also visit our Cough, Cold & Flu Hub for broader comparisons and seasonal-care guides.


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  • Perrigo Cetirizine 10mg - 300 Tablets (Zyrtec) Padagis Cetirizine 10mg - 300 Tablets (Zyrtec)  Benefits

    Perrigo Cetirizine Hydrochloride 10 mg - 300 Tablets | Zyrtec

    Perrigo
    $17.99
    Cetirizine Hydrochloride 10 mg Tablets – 300 Count | Generic Zyrtec® by Perrigo 24-Hour Allergy Relief for Less Perrigo Cetirizine Hydrochloride 10 mg delivers the same FDA-approved active ingredient...
  • 5 pack of Major Nasal Decongestant Spray 1 fl oz bottles – generic Afrin pump spray for congestion relief Promotional image of Major Nasal Decongestant Spray 5 Pack – shows free shipping, made in USA, compares to Afrin, and highlights 5 fl oz total for sinus and nasal congestion relief

    Major Nasal Decongestant Spray - 1 fl oz | Compare to Afrin No Drip (5 Pack)

    Major Pharmaceuticals
    $34.99
    Major Nasal Decongestant Spray – Oxymetazoline HCl 0.05% – 5 fl oz (5-Pack Bundle) | Compare to Afrin® No Drip Fast, 12-Hour Relief from Nasal Congestion and Sinus Pressure Stock up and save on...
  • Major Cough & Cold HBP - 16 Tablets (Coricidin HBP Cough & Cold)- New Box Major Cough & Cold HBP New Box vs Old Box

    Major Cough & Cold HBP - 16 Tablets | Coricidin HBP

    Major Pharmaceuticals
    $5.99
    Major Cough & Cold HBP – 16 Tablets | Compare to Coricidin® HBP Cough & Cold Safe and Effective Decongestant-Free Cold Relief Major Cough & Cold HBP provides decongestant-free relief for your...
  •  Major Banophen Diphenhydramine 50mg - 100 Capsules (Generic Benadryl)  Major Banophen Diphenhydramine 50mg - 100 Capsules (Generic Benadryl)  Drug Facts

    Major Banophen 50 mg - 100 Capsules | Benadryl

    Major Pharmaceuticals
    $6.99
    Major Banophen Diphenhydramine 50 mg – 100 Capsules | Compare to Benadryl® Compare to the active ingredient in Benadryl® Allergy Experience effective relief with Major Banophen 50 mg Capsules. This...
  • Major Allergy Tablets Chlorpheniramine Maleate 4 mg - 100 Tablets | Chlor-Trimeton Major Allergy Tablets Chlorpheniramine Maleate 4 mg - 100 Tablets | Chlor-Trimeton New package vs old package

    Major Allergy Tablets Chlorpheniramine Maleate 4 mg - 100 Tablets | Chlor-Trimeton

    Major Pharmaceuticals
    $7.99
    Major Allergy Tablets 4 mg Chlorpheniramine Maleate – 100 Count | Compare to Chlor-Trimeton® Fast 4-Hour Relief from Sneezing, Runny Nose, and Itchy, Watery Eyes Relieve bothersome indoor and outdoor...
  •  Major Loratadine 10 mg- 300 Tablets (Generic Claritin)  Major Loratadine 10 mg- 300 Tablets (Generic Claritin) Drug Facts

    Major Loratadine 10 mg - 300 Tablets | Claritin

    Major Pharmaceuticals
    $6.99
    Major Non-Drowsy Allergy Relief Loratadine 10 mg Tablets – 300 Count | Compare to Claritin® 24-Hour Non-Drowsy Relief for Indoor and Outdoor Allergies Relieve stubborn indoor and outdoor allergy...
  • Front view of GoodSense Cough & Cold HBP for High Blood Pressure Tablets 16 count box, a generic equivalent to Coricidin HBP Cough & Cold. GoodSense Cough & Cold HBP has the same active ingredients at Coricidin HBP Cough & Cold with no decongestants like pseudoephedrine or phenylephrine

    GoodSense Cough & Cold HBP - 16 Tablets | Compare to Coricidin HBP

    GoodSense
    $5.79
    GoodSense Cough & Cold HBP – 16 Tablets | Safe for High Blood Pressure Effective cold relief for people managing hypertension. GoodSense Cough & Cold HBP provides decongestant-free relief for cough,...
  • Major 12 Hour Nasal Decongestant Spray 0.05% - 1 fl oz (Afrin) New Box Woman breathing easily

    Major Nasal Decongestant Spray - 1 fl oz | Compare to Afrin No Drip

    Major Pharmaceuticals
    $9.99
    Major Nasal Decongestant Spray – Oxymetazoline HCl 0.05% – 1 fl oz | Compare to Afrin® No Drip Fast, 12-Hour Relief from Nasal Congestion and Sinus Pressure Relieve severe nasal congestion and sinus...
  • Major Diphenhydramine 25mg - 100 Capsules (Benadryl) Major Diphenhydramine 25mg - 100 Capsules (Benadryl) Drug Facts

    Major Banophen 25 mg - 100 Capsules | Benadryl

    Major Pharmaceuticals
    $6.99
    Major Banophen Diphenhydramine 25 mg – 100 Capsules | Compare to Benadryl® Compare to the active ingredient in Benadryl® Allergy Relieve your allergy symptoms for less with Major Banophen 25 mg...
  • Major Original Nasal Decongestant Spray 12 Hour Relief Oxymetazoline - 0.5 fl oz | Afrin Original Nasal Spray - 5 Pack Major Original Nasal Decongestant Spray New Box
    Sale 22%
    Sale 22%

    Major Nasal Decongestant Spray - 0.5 fl oz | Compare to Afrin Original (5 Pack)

    Major Pharmaceuticals
    $17.99
    $13.99
    Major Maximum Strength Nasal Decongestant Spray – 0.5 fl oz | 12 Hour Relief (5 Pack) Major Maximum Strength Nasal Decongestant Spray – 0.5 fl oz (5 Pack) provides fast, long-lasting relief from...
  • Major Original Nasal Decongestant Spray 12 Hour Relief - 0.5 Fl Oz (Afrin) New Blue Box Major Original Nasal Decongestant Spray 12 Hour Relief - 0.5 Fl Oz | Afrin - New Look
    Sale 43%
    Sale 43%

    Major Nasal Decongestant Spray - 0.5 fl oz | Compare to Afrin Original

    Major Pharmaceuticals
    $6.99
    $3.99
    Major Maximum Strength Nasal Decongestant Spray – 0.5 oz | Compare to Afrin Original Major Maximum Strength Nasal Decongestant Spray provides fast, long-lasting relief from nasal congestion caused by...
  • Main product image showing 24 bottles of Major Nasal Decongestant Spray 0.05% – Compare to Afrin Promotional image of 24-pack Major Nasal Decongestant Spray showing free shipping, Compare to Afrin, Made in USA, 24 fl oz total, and sinus congestion relief

    Major Nasal Decongestant Spray - 1 fl oz | Compare to Afrin No Drip (24 Pack)

    Major Pharmaceuticals
    $99.99
    Major Nasal Decongestant Spray – Oxymetazoline HCl 0.05% – 24 fl oz (24-Pack Bundle) | Compare to Afrin® No Drip Fast, 12-Hour Relief from Nasal Congestion and Sinus Pressure Stock up and save on...
  • Main product image showing 15 bottles of Major Nasal Decongestant Spray 0.05% Oxymetazoline Promotional image of 15-pack Major Nasal Decongestant Spray showing Free Shipping, Compare to Afrin, Made in USA, 15 bottles total, and sinus congestion relief

    Major Nasal Decongestant Spray - 1 fl oz | Compare to Afrin No Drip (15 Pack)

    Major Pharmaceuticals
    $69.99
    Major Nasal Decongestant Spray – Oxymetazoline HCl 0.05% – 15 fl oz (15-Pack Bundle) | Compare to Afrin® No Drip Fast, 12-Hour Relief from Nasal Congestion and Sinus Pressure Stock up and save on...
  • Major Cetirizine 10mg- 90 tablets (Generic Zyrtec) Box Major Cetirizine 10mg- 90 tablets (Generic Zyrtec) Drug Facts

    Major Cetirizine Antihistamine 10mg - 90 Tablets | Zyrtec

    Major Pharmaceuticals
    $7.49
    Major Original Prescription Strength Cetirizine – 90 Tablets | Generic Zyrtec® 24-Hour Allergy Relief for Indoor & Outdoor Symptoms Major Cetirizine Hydrochloride 10 mg offers prescription-strength...
  • Rugby Anti-Itch Lotion 4-Pack – Same Ingredients as Sarna, Free Shipping Included Woman applying anti-itch lotion to her arm in a home setting, representing Rugby Anti-Itch Lotion with camphor 0.5% and menthol 0.5%

    Rugby Anti-Itch Lotion - 7.5 fl oz | Sarna (4 Pack)

    Rugby Laboratories
    $39.99
    Rugby Anti-Itch Lotion – 7.5 fl oz (4-Pack Bundle) | Compare to Sarna® Original Steroid-Free, Cooling Relief for Itchy and Irritated Skin Find lasting relief with this 4-pack of Rugby Anti-Itch...
  • 10 Pack of GoodSense Cough & Cold HBP for High Blood Pressure Tablets 16 count box 10 Pack of GoodSense Cough & Cold HBP for High Blood Pressure Tablets 16 count box, a generic equivalent to Coricidin HBP Cough & Cold with free shipping.

    GoodSense Cough & Cold HBP - 16 Tablets | Compare to Coricidin HBP (10 Pack)

    GoodSense
    $27.99
    GoodSense Cough & Cold HBP – 16 Tablets (10 Pack) | Compare to Coricidin Cough & Cold HBP - Decongestant-Free Cold Relief Safe cold relief for people with high blood pressure. GoodSense Cough & Cold...
  • Major Banophen 50 mg - 100 Capsules | Benadryl (2 Pack) Major Banophen 50 mg with Highlights - 2 Pack

    Major Banophen 50 mg - 100 Capsules | Benadryl (2 Pack)

    Major Pharmaceuticals
    $11.99
    Major Banophen Diphenhydramine 50 mg – 2 Pack (200 Capsules) | Compare to Benadryl® Compare to the active ingredient in Benadryl® Allergy Maximize your relief and savings with this 2-Pack of Major...
  • Rugby Diphenhydramine HCl 25 mg - 100 Tablets | Benadryl Allergy Ultratabs Rugby Diphenhydramine HCl 25 mg - 100 Tablets | Benadryl Allergy Ultratabs - full label

    Rugby Diphenhydramine 25 mg - 100 Tablets | Benadryl Ultratab Tablets

    Rugby Laboratories
    $11.99
    Rugby Diphenhydramine HCl 25 mg – 100 Tablets | Compare to Benadryl® Allergy Ultratabs Dependable Multi-Symptom Relief for Allergies and the Common Cold Stop the sneeze and dry up the drip with Rugby...
  • Major Allergy Tablets Chlorpheniramine Maleate 4 mg - 100 Tablets | Chlor-Trimeton (5 Pack) Major Allergy Tablets Chlorpheniramine Maleate 4 mg - 100 Tablets | Chlor-Trimeton (5 Pack) with free shipping

    Major Allergy Tablets Chlorpheniramine Maleate 4 mg - 100 Tablets | Chlor-Trimeton (5 Pack)

    Major Pharmaceuticals
    $17.99
    Major Allergy Tablets 4 mg Chlorpheniramine Maleate – 500 Count (5-Pack Bundle) | Compare to Chlor-Trimeton® Fast 4-Hour Relief from Sneezing, Runny Nose, and Itchy, Watery Eyes Relieve bothersome...
  • 24Pack of GoodSense Cough & Cold HBP for High Blood Pressure Tablets 16 count box 24 Pack of GoodSense Cough & Cold HBP for High Blood Pressure Tablets 16 count box, a generic equivalent to Coricidin HBP Cough & Cold with free shipping.

    GoodSense Cough & Cold HBP - 16 Tablets | Compare to Coricidin HBP (24 Pack)

    GoodSense
    $56.99
    GoodSense Cough & Cold for High Blood Pressure – 24 Pack | Compare to Coricidin® HBP Cough & Cold GoodSense Cough & Cold HBP provides safe, multi-symptom cold relief specifically formulated for...
  • 4 bottles of Major Calamine Lotion – front label with brand name shown, over-the-counter itch relief for poison ivy, oak, and heat rash Major Calamine Lotion 4-Pack – relief of itching from poison ivy, poison oak, insect bites, and heat rash

    Major Calamine Lotion - 6 fl oz | Caladryl (4 Pack)

    Major Pharmaceuticals
    $27.99
    Major Calamine Lotion – 8% Calamine & 8% Zinc Oxide – 6 fl oz (4-Pack) Maximum Bulk Savings for Poison Ivy, Oak, Sumac, and Heat Rash Relief Major Calamine Lotion is a pharmacist-trusted,...
  • Rugby Maximum Strength Hydrocortisone Cream 1% with Aloe, 1 oz, compared to the active ingredient in Cortizone-10 with Aloe - 3 Pack Woman applying Rugby Hydrocortisone Cream 1% with Aloe to her arm for temporary relief of itchy, irritated skin

    Rugby Hydrocortisone Cream 1% with Aloe - 1 oz | Cortizone-10 (3 Pack)

    Rugby Laboratories
    $16.99
    Rugby Hydrocortisone Cream 1% with Aloe – 1 oz (3-Pack Bundle) | Compare to Cortizone 10® Maximum Strength, Soothing Itch Relief in a Convenient 3-Pack Keep soothing relief within reach at home, at...
  • Major Allergy Tablets Chlorpheniramine Maleate 4 mg - 100 Tablets | Chlor-Trimeton (3 Pack) Major Allergy Tablets Chlorpheniramine Maleate 4 mg - 100 Tablets | Chlor-Trimeton (3 Pack) with free shipping

    Major Allergy Tablets Chlorpheniramine Maleate 4 mg - 100 Tablets | Chlor-Trimeton (3 Pack)

    Major Pharmaceuticals
    $13.99
    Major Allergy Tablets 4 mg Chlorpheniramine Maleate – 300 Count (3-Pack Bundle) | Compare to Chlor-Trimeton® Fast 4-Hour Relief from Sneezing, Runny Nose, and Itchy, Watery Eyes Relieve bothersome...
  • Major Cetirizine HCl 10 mg - 45 Tablets | Zyrtec Major Cetirizine HCl 10 mg - 45 Tablets | Compare to active ingredient in Zyrtec

    Major Cetirizine 10 mg - 45 Tablets | Compare to Zyrtec

    Major Pharmaceuticals
    $10.99
    Major Cetirizine Hydrochloride 10 mg – 45 Tablets | Compare to Zyrtec® Powerful 24-Hour Relief from Indoor and Outdoor Allergy Symptoms Experience prescription-strength, 24-hour relief from seasonal...
  • Major Banophen 25 mg - 100 Capsules | Benadryl (2 Pack) Major Banophen 25 mg with Highlights - 2 Pack

    Major Banophen 25 mg - 100 Capsules | Benadryl (2 Pack)

    Major Pharmaceuticals
    $10.98
    Major Banophen Diphenhydramine 25 mg – 2 Pack (200 Capsules) | Compare to Benadryl® Compare to the active ingredient in Benadryl® Allergy Double your value with this 2-Pack of Major Banophen 25 mg...
  • Close-up of Rugby Dextromethorphan HBr 15 mg Softgels Front Label – 4 Pack Smiling woman holding a softgel capsule for dry cough relief

    Rugby Dextromethorphan HBr 15mg - 20 Softgels | Robitussin CoughGels (4 Pack)

    Rugby Laboratories
    $19.99
    Rugby Dextromethorphan HBr 15 mg Softgels – 80 Count (4-Pack Bundle) | Compare to Robitussin® CoughGels Fast, Effective, Non-Drowsy Cough Suppression for Targeted Relief Quiet persistent, dry coughs...
  • Oncor Diphenhydramine Hydrochloride Oral Cherry Flavored Solution - 16 fl oz - Alcohol Free Oncor Diphenhydramine Hydrochloride Oral Cherry Flavored Solution - 16 fl oz - Compare to Benadryl Liquid Allergy

    Oncor Diphenhydramine Oral Solution 12.5 mg / 5 mL - 16 fl oz | Compare to Benadryl Allergy Liquid

    Oncor Pharmaceuticals
    $12.99
    Oncor Diphenhydramine Hydrochloride Oral Solution – 16 fl oz | Compare to Active Ingredient in Benadryl® Allergy Liquid Fast-Acting, Alcohol-Free Allergy and Cold Relief in an Easy-to-Take...
  • Front view of GoodSense Allergy Relief Chlorpheniramine Maleate 4 mg 4-Hour Tablets 24 count box, a generic equivalent to Chlor-Trimeton. Drug facts label for GoodSense Allergy Relief Chlorpheniramine Maleate 4 mg 4-Hour Tablets 24 count box, a generic equivalent to Chlor-Trimeton.
    Sale 40%
    Sale 40%

    GoodSense Allergy Relief Chlorpheniramine Maleate 4 mg - 24 Tablets | Compare to Chlor-Trimeton

    GoodSense
    $4.99
    $2.99
    GoodSense® 4-Hour Allergy Relief Tablets, Chlorpheniramine Maleate 4 mg Find fast, reliable relief from common allergy symptoms with GoodSense® 4-Hour Allergy Relief tablets. Each tablet contains...
  • A 16 oz bottle of Geri-Care Geri-Dryl Liquid Allergy Relief featuring a pink and blue label on a plain white background. Marketing graphic of a hand holding Geri-Dryl liquid medicine next to text highlights for fast-acting formula, multi-symptom relief, and alcohol-free properties.

    Geri-Care Geri-Dryl Liquid Allergy Relief Diphenhydramine 12.5 mg / 5 mL - 16 fl oz | Compare to Benadryl Liquid Allergy

    Geri-Care
    $13.99
    Geri-Care Geri-Dryl Liquid Allergy Relief Diphenhydramine 12.5 mg / 5 mL – 16 fl oz | Compare to Active Ingredient in Benadryl® Allergy Liquid Fast-Acting, Alcohol-Free Allergy Relief Get reliable,...
  •  Major Loratadine 10 mg- 100 Tablets (Generic Claritin)  Major Loratadine 10 mg- 100 Tablets (Generic Claritin)
    Sale 15%
    Sale 15%

    Major Loratadine 10 mg - 100 Tablets | Claritin

    Major Pharmaceuticals
    $12.99
    $10.99
    Major Non-Drowsy Allergy Relief Loratadine 10 mg Tablets – 100 Count | Compare to Claritin® 24-Hour Non-Drowsy Relief for Indoor and Outdoor Allergies Relieve stubborn indoor and outdoor allergy...
  • Major Nasal Decongestant Spray Squeeze Bottle - 2 Pack with free shipping. Major Nasal Decongestant Spray - new look
    Sale 30%
    Sale 30%

    Major Nasal Decongestant Spray - 0.5 fl oz | Compare to Afrin Original (2 Pack)

    Major Pharmaceuticals
    $9.99
    $6.99
    Major Maximum Strength Nasal Decongestant Spray – 0.5 fl oz (2 Pack) | Compare to Afrin Original® Major Maximum Strength Nasal Decongestant Spray – 2 Pack delivers fast, powerful congestion relief...
  • Major Non-Drowsy Allergy Relief Loratadine 10 mg - 30 Tablets (Claritin) Major Non-Drowsy Allergy Relief Loratadine 10 mg - 30 Tablets (Claritin) Drug Facts

    Major Loratadine 10 mg - 30 Tablets | Claritin

    Major Pharmaceuticals
    $6.99
    Major Non-Drowsy Allergy Relief Loratadine 10 mg Tablets – 30 Count | Compare to Claritin® 24-Hour Non-Drowsy Relief for Indoor and Outdoor Allergies Relieve stubborn indoor and outdoor allergy...
  • Perrigo Cetirizine Hydrochloride 10 mg - 300 Tablets | Zyrtec (2 Pack) Perrigo Cetirizine Hydrochloride 10 mg - 300 Tablets | Zyrtec (2 Pack)

    Perrigo Cetirizine Hydrochloride 10 mg - 300 Tablets | Zyrtec (2 Pack)

    Perrigo
    $29.99
    Cetirizine Hydrochloride 10 mg – 600 Tablets (2 Pack) | Generic Zyrtec® by Padagis / Perrigo Stock Up & Save: Bulk Allergy Relief + Free Shipping Save more with our best value pack. This 2-Pack...