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Over-The-Counter


Affordable Over-the-Counter Medicines Without the Brand-Name Price

Looking for low-cost relief without sacrificing quality? Our over-the-counter selection includes trusted generics that compare to top brands like Mucinex®, Colace®, Robitussin®, Citrucel®, and Phazyme®—all at everyday low prices.

From stool softeners like Docusate Sodium to guaifenesin cough syrups without dextromethorphan, we stock remedies for constipation, cough and cold, indigestion, hemorrhoids, and more. Many of our products are made by trusted manufacturers such as Foster & Thrive®, Rugby®, Major®, and Perrigo®.

  • Constipation Relief: Docusate Sodium, Bisacodyl, PEG 3350
  • Cough & Cold: Robafen DM, Liquid Guaifenesin, Mucus Relief
  • Pain Relief: Capsaicin Cream, Lidocaine Patches, Menthol Rubs
  • Allergies: Diphenhydramine, Cetirizine, Chlorpheniramine
  • Digestive Support: Simethicone, Methylcellulose, Antacids

Need help finding something? Check out our blog or contact us for personalized assistance. We offer fast shipping and discounts on bulk packs for caregivers, clinics, and families stocking up.

What ailment can we help you with today?


⭐ Top Over-the-Counter Deals

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  •  Major Simethicone Antiflatulent 80 mg - 100 Chewable Tablets Major Simethicone 80mg Chewable Mint Tablets Relieves Gas, Pressure and Bloating

    Major Simethicone 80 mg - 100 Chewable Tablets Mint Flavor

    Major Pharmaceuticals
    $6.99
    Major Simethicone 80 mg Chewable Tablets – 100 Count, Mint Flavor Fast, affordable relief from gas and bloating. These simethicone 80 mg chewable tablets from Major help break up gas bubbles in the stomach and intestines—relieving pressure,...
  • Major Diphenhydramine 25mg - 100 Capsules (Benadryl) Major Diphenhydramine 25mg - 100 Capsules (Benadryl) Drug Facts

    Major Banophen 25 mg - 100 Capsules | Benadryl

    Major Pharmaceuticals
    $6.99
    Major Banophen Diphenhydramine 25 mg – 100 Capsules | Compare to Benadryl® Compare to the active ingredient in Benadryl® Allergy Relieve your allergy symptoms for less with Major Banophen 25 mg Capsules. This bottle contains 100 capsules of...
  • Major Calcium Oyster Shell 500 mg - 300 Tablets Major Calcium Oyster Shell 500 mg - 300 Tablets Supplement Facts

    Major Calcium Oyster Shell 500 mg - 300 Tablets

    Major Pharmaceuticals
    $9.99
    Major Calcium Oyster Shell 500 mg - 300 Tablets  New Formula  Calcium Supplement  500 mg - 300 tablets  Contains Soy Expiration Date: 12-2026 Ingredients Active Ingredients: Calcium (as oyster shell) - 500 mg, Sodium - 5...
  • Major Fiber Therapy Powder Methylcellulose Orange Flavor - 16oz | Citrucel (4 Pack) Major Fiber Therapy 4 Pack - Compare to Citrucel

    Major Fiber Therapy Methylcellulose Powder – 16 oz | Compare to Citrucel (4 Pack)

    Major Pharmaceuticals
    $48.99
    Major Fiber Therapy Methylcellulose Powder – 16 oz (4 Pack) | Compare to Citrucel® The Direct Replacement for Citrucel® with Sugar Stock up and save with this 4-pack of Major Fiber Therapy Powder. This is the direct generic replacement for...
  • TRUEplus Glucose Tablets - Orange Flavor  50 Tablets TRUEplus 50 Orange Glucose Tablets  Nutrition Facts

    True Plus Glucose Tablets - Orange Flavor 50 Tablets

    True Plus
    $4.99
    TruePlus Glucose Tablets – Orange Flavor | 50-Count Bottle Fast-Acting Glucose for Hypoglycemia & Low Blood Sugar Episodes TruePlus Glucose Tablets provide quick, reliable relief from low blood sugar. Each chewable tablet contains...
  • Rugby Ultra Strength Simethicone 180 mg - 60 Softgels | Phazyme Ultra Strength (2 Pack) Rugby Simethicone 180 mg with Highlights - 2 Pack

    Rugby Simethicone 180 mg - 60 Softgels | Ultra Strength Phazyme (2 Pack)

    Rugby Laboratories
    $11.99
    Rugby Simethicone 180 mg – 60 Softgels | Phazyme Ultra Strength (2 Pack) Rugby Simethicone 180 mg softgels provide fast relief from gas-related pressure, bloating, and abdominal discomfort. This 2 pack includes two 60-count bottles (120 total...
  • Major Maximum Strength Lice Killing Shampoo New Look Lice Killing Shampoo - Fast Shipping

    Major Lice Killing Shampoo - 4 fl oz | RID Shampoo

    Major Pharmaceuticals
    $11.99
    Major Maximum Strength Lice Killing Shampoo - 4 fl oz Introducing Major Maximum Strength Lice Killing Shampoo, a powerful solution designed to effectively eliminate lice infestations and provide relief from associated symptoms. Compare to the active...
  • Major Bismuth Subsalicylate - 30 Tablets | Pepto-Bismol (6 Pack) Major Bismuth Subsalicylate - 30 Tablets | Pepto-Bismol (6 Pack)

    Major Bismuth Subsalicylate - 30 Tablets | Pepto-Bismol (6 Pack)

    Major Pharmaceuticals
    $18.96
    Major Bismuth Subsalicylate 262 mg – 30 Chewable Tablets (6 Pack) | Generic Pepto-Bismol® Alternative Major® Bismuth Subsalicylate Chewable Tablets provide the same trusted active ingredient as Pepto-Bismol® to relieve diarrhea,...
  • Major Adults Extra Strength Acetaminophen 500 mg - 1000 Caplets (Tylenol) Major Adults Extra Strength Acetaminophen 500 mg - 1000 Caplets (Tylenol) - Full Drug Facts Label

    Major Acetaminophen 500 mg - 500 Caplets | Extra Strength Tylenol

    Major Pharmaceuticals
    $14.99
    Major Extra Strength Acetaminophen 500 mg – 500 Caplets | Generic Tylenol Alternative Looking for a reliable Generic Tylenol option in bulk? This 500-count bottle of Major Extra Strength Acetaminophen 500 mg caplets delivers the same active...
  • Rugby Magnesium Oxide 420 mg Dietary Supplement - 100 Tablets Rugby Magnesium Oxide 420 mg Dietary Supplement - 100 Tablets Supplemental Facts

    Rugby Magnesium Oxide 420 mg Dietary Supplement - 100 Tablets

    Rugby Laboratories
    $9.99
    Rugby Magnesium Oxide 420 mg Dietary Supplement - 100 Tablets  Pure Magnesium for Sleep, Stress Relief and Muscle Relaxation - Rugby Magnesium Relieve stress, anxiety and muscle tension with Rugby Magnesium supplements. Our highly bioavailable...
  • Rugby Maximum Strength Pain Relief Patch 4% Lidocaine - 30 Patches (Aspercreme) Rugby Maximum Strength Pain Relief Patch 4% Lidocaine - 30 Patches (Aspercreme) AD

    Rugby Lidocaine 4% Pain Relief Patch - 30 Patches | Aspercreme

    Rugby Laboratories
    $44.99
    Rugby Lidocaine 4% Pain Relief Patches – 30 Pack | Compare to Aspercreme® Get bulk relief at the best value. The Rugby Lidocaine 4% Pain Relief Patch is a trusted generic alternative to Aspercreme®, designed to numb away nerve, muscle, and...
  • Rugby PEG Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz (MiraLAX) Bottle of Rugby PEG 3350 osmotic laxative on a bathroom counter next to a large green fern and a sink faucet.

    Rugby PEG Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | Miralax

    Rugby Laboratories
    $19.99
    Rugby PEG 3350 Powder – 17.9 oz (30 Doses) | Compare to Miralax Rugby PEG 3350 Powder is a trusted, unflavored osmotic laxative that provides gentle, effective relief from occasional constipation. It contains the same active ingredient as...
  • Rugby Hemorrhoidal Ointment - 2 oz | Preparation H Rugby Hemorrhoidal Ointment - 2 oz | Preparation H - Spicy Food

    Rugby Hemorrhoidal Ointment - 2 oz | Preparation H

    Rugby Laboratories
    $7.29
    Rugby Hemorrhoidal Ointment – 2 oz with Applicator | Compare to Preparation H® Compare to the active ingredients in Preparation H® Ointment. Rugby Hemorrhoidal Ointment provides fast relief from hemorrhoid pain, itching, swelling, and...
  • 12 pack of Rugby Sodium Chloride Ophthalmic Solution 5% drops – Muro 128 alternative for corneal edema Rugby Sodium Chloride 5 Percent Eye Drops 12 Pack – Hypertonic Saline Solution for Corneal Swelling and Fuchs’ Dystrophy

    Rugby Sodium Chloride Ophthalmic Solution 5% | Muro 128 (12 Pack)

    Rugby Laboratories
    $69.99
    Rugby Sodium Chloride Ophthalmic Solution 5% – 12 Pack | Compare to Muro 128 Drops Managing corneal edema long-term? This value-sized 12 pack of Rugby Sodium Chloride Ophthalmic Solution 5% offers the same hypertonic saline strength used in Muro...
  • Rugby Benzoyl Peroxide Lotion 5% - 1 fl oz Rugby Benzoyl Peroxide Lotion 5% - 1 fl oz Bottle

    Rugby Benzoyl Peroxide Lotion 5% - 1 oz (Oxy Balance Lotion)

    Rugby Laboratories
    $7.49
    Rugby Benzoyl Peroxide Lotion 5% - 1 fl oz Acne medication Helps dry oily kin Odorless and colorless Helps clear acne pimples Greaseless vanishing formula  Expiration Date: 11-2024 Ingredients Active Ingredient: Benzoyl Peroxide...
  • Major Original Nasal Decongestant Spray 12 Hour Relief Oxymetazoline - 0.5 fl oz | Afrin Original Nasal Spray - 5 Pack Major Original Nasal Decongestant Spray New Box

    Major Nasal Decongestant Spray - 0.5 fl oz | Compare to Afrin Original (5 Pack)

    Major Pharmaceuticals
    $17.99
    Major Maximum Strength Nasal Decongestant Spray – 0.5 fl oz | 12 Hour Relief (5 Pack) Major Maximum Strength Nasal Decongestant Spray – 0.5 fl oz (5 Pack) provides fast, long-lasting relief from nasal congestion due to colds, allergies, and...
  • Rugby Vitamin D3 25 mcg Dietary Supplement - 100 Tablets Rugby Vitamin D3 25 mcg (1000 IU) - Ingredients

    Rugby Vitamin D3 25 mcg (1000 IU) - 100 Tablets

    Rugby Laboratories
    $6.99
    Rugby Vitamin D3 25 mcg (1000 IU) – 100 Tablets | Daily Immune & Bone Support Rugby Vitamin D3 1000 IU supports healthy bones, immune system function, and calcium absorption in a small, easy-to-swallow tablet. Each tablet delivers 25 mcg (1000...
  • Rugby Capsaicin Cream - 3 Pack Rugby Capsaicin Cream - Zostrix Generic - 3 Pack

    Rugby Capsaicin Cream 0.025% - 2 oz | Zostrix (3 Pack)

    Rugby Laboratories
    $17.99
    Rugby Capsaicin Cream 0.025% – 2 oz (3 Pack) | Compare to Zostrix® Compare to the active ingredient in Zostrix® Stock up on effective pain relief with this 3-pack of Rugby Capsaicin Cream 0.025%. Formulated with the same active ingredient...
  • Major Original Nasal Decongestant Spray 12 Hour Relief - 0.5 Fl Oz (Afrin) New Blue Box Major Original Nasal Decongestant Spray 12 Hour Relief - 0.5 Fl Oz | Afrin - New Look

    Major Nasal Decongestant Spray - 0.5 fl oz | Compare to Afrin Original

    Major Pharmaceuticals
    $5.99
    Major Maximum Strength Nasal Decongestant Spray – 0.5 oz | Compare to Afrin Original Major Maximum Strength Nasal Decongestant Spray provides fast, long-lasting relief from nasal congestion caused by colds, allergies, or sinus pressure. Each spray...
  • Major Docusate Sodium 250 mg Dosage - Buy in Bulk Major Docusate Sodium 250 mg - 500 Softgels

    Major Docusate Sodium 250 mg - 100 Softgels | Extra Strength Colace (5 Pack)

    Major Pharmaceuticals
    $34.99
    Major Extra Strength Docusate Sodium 250 mg Softgels – 5 Pack (500 Count) | Compare to Colace® This 5-pack of Major Docusate Sodium 250 mg softgels provides a 500-dose supply of gentle, pharmacy-grade stool softener. It’s the ideal choice...
  • Rugby Zinc Sulfate 220 mg Dietary Supplement - 100 Tablets - 4 Pack Rugby Zinc Sulfate 220 mg - 100 Tablets - 4 Pack

    Rugby Zinc Sulfate 220 mg - 100 Tablets (4 Pack)

    Rugby Laboratories
    $17.96
    Rugby Zinc Sulfate 220 mg Dietary Supplement – 100 Tablets – 4 Pack Rugby Zinc Sulfate 220 mg delivers 50 mg of elemental zinc per tablet to help support immune function, skin healing, and overall wellness. This 4-pack contains 400 tablets...
  • Rugby Senna Syrup - Senna Leaf Extract 176mg / 5mL Dietary Supplement - 8 Fl Oz (3 Pack) Rugby Senna Syrup - Senna Leaf Extract 176mg / 5mL Dietary Supplement - 8 Fl Oz Chocolate Flavor

    Rugby Senna Syrup 8 fl oz (3 Pack) – 176 mg/5 mL for Constipation Relief

    Rugby Laboratories
    $37.99
    Rugby Senna Syrup 8 fl oz (3 Pack) – 176 mg/5 mL for Constipation Relief Get gentle, overnight relief from occasional constipation with this 3 pack of Rugby Senna Syrup. Each teaspoon delivers 176 mg of senna leaf extract (as sennosides), a...
  • Rugby Preservative-Free Lubricant Eye Drops Dry Eyes 0.01 Fl Oz - 30 Single-Use Containers Guide to Generic Eye Drops

    Rugby Lubricant Eye Drops - 30 Single-Use Containers | Refresh Plus

    Rugby Laboratories
    $11.99
    Rugby Lubricant Eye Drops 0.5% – 30 Sterile Single-Use Containers | Compare to Refresh Plus® Moisturizing Relief for Dry, Irritated Eyes Get immediate, soothing relief with Rugby Lubricant Eye Drops. These sterile, single-use droppers contain...
  • Rugby Budesonide Nasal Allergy Spray 32 mcg - 120 Metered Sprays (Rhinocort) Rugby Budesonide Nasal Allergy Spray 32 mcg - 120 Metered Sprays (Rhinocort) Bottle

    Rugby Budesonide Nasal Allergy Spray 32 mcg - 120 Sprays | Rhinocort

    Rugby Laboratories
    $12.99
    Breathe Easier with Budesonide Nasal Spray Budesonide nasal spray delivers fast relief from congestion and sinus pressure. The active ingredient budesonide reduces inflammation and opens nasal passages within hours, providing 12 hours of clearer...
  • Major CertaVite Senior Multivitamin/Multimineral Supplemet - 60 Tablets Theragran Generic Alternatives: Rugby Therems vs Major CertaVite Senior vs Major CertaVite with Antioxidants

    Major CertaVite Senior Multivitamin - 60 Tablets | Theragran-M

    Major Pharmaceuticals
    $7.99
    Major CertaVite Senior Multivitamin – 60 Tablets | Compare to Theragran-M® Compare to Theragran-M® — an iron-free multivitamin for adults 50+, formulated with essential vitamins, antioxidants, and minerals for daily senior wellness...
  • rugby sodium chloride hypertonicity ophthalmic ointment 4 pack with free shipping rugby sodium chloride hypertonicity ophthalmic ointment

    Rugby Sodium Chloride Hypertonicity Ointment 5% | Muro 128 (4 Pack)

    Rugby Laboratories
    $52.99
    Rugby Sodium Chloride Ophthalmic Ointment 5% – 4 Pack (3.5 g Tubes) | Compare to Muro 128 Get dependable, multi-month relief from corneal edema with this 4-pack of Rugby Sodium Chloride Hypertonicity Ophthalmic Ointment 5%. Each sterile 3.5 g tube...
  • Rugby Arthritis Pain Relieving Cream - 3 Pack Rugby Arthritis Pain Relieving Cream Capsaicin 0.075% - 3 Pack

    Rugby Arthritis Pain Relieving Cream - 2 oz | Zostrix HP (3 Pack)

    Rugby Laboratories
    $20.98
    Rugby Capsaicin Cream 0.075% – 2 oz (3 Pack) | Strong Zostrix HP® Alternative Need powerful pain relief for arthritis or nerve pain? This 3-pack of Rugby Capsaicin Cream 0.075% contains the same active ingredient as Zostrix HP® — a...
  • Rugby Chest Congestion Relief Guaifenesin 100mg Cough Syrup | Robitussin - Full Case Pack (12 bottles) Rugby Chest Congestion Relief Guaifenesin 100mg Cough Syrup | Robitussin - 12 Bottles Bulk Price with Free Shipping

    Rugby Chest Congestion Relief Guaifenesin 100 mg Cough Syrup - 16 fl oz | Compare to Robitussin (12 Pack)

    Rugby Laboratories
    $69.99
    Rugby Chest Congestion Relief Guaifenesin 100 mg Cough Syrup – 16 fl oz (12 Pack) | Compare to Robitussin Bulk savings on non-drowsy chest congestion relief. This 12-pack of Rugby Chest Congestion Relief provides guaifenesin 100 mg per 5 mL —...
  • Rugby Maximum Strength Pain Relieving Cream | Thera-Gesic (3 Pack) Rugby Maximum Strength Pain Relieving Cream - 3 Pack

    Rugby Pain Relieving Cream – 3 oz | Compare to Thera-Gesic (3 Pack)

    Rugby Laboratories
    $19.99
    Rugby Pain Relieving Cream – 3 oz (3 Pack) | Compare to Thera-Gesic® Maximum Strength Relief for Aches & Pains Stock up and save with this 3-pack of Rugby Pain Relieving Cream. Containing a total of 9 oz (three 3 oz tubes), this bundle...
  • Front label of Rugby Dextromethorphan HBr 15 mg 5-pack softgel bottles Smiling woman holding softgel capsule for non-drowsy cough relief

    Rugby Dextromethorphan HBr 15mg - 20 Softgels | Robitussin (5 Pack)

    Rugby Laboratories
    $21.99
    Rugby Dextromethorphan HBr 15 mg Softgels – 5 Pack (100 Softgels Total) | Non-Drowsy Cough Suppressant Reliable, non-drowsy relief for dry, persistent coughs. Each Rugby softgel contains Dextromethorphan Hydrobromide 15 mg, the same active...
  • Major Robafen DM Raspberry Flavor Non-Drowsy - 8 Fl Oz Major Robafen DM Raspberry Flavor Non-Drowsy - 8 Fl Oz - Great tasting cough medicine in a large size

    Major Robafen DM Cough Syrup – 8 fl oz | Compare to Robitussin DM

    Major Pharmaceuticals
    $9.99
    Major Robafen DM Cough Syrup – 8 fl oz | Compare to Robitussin DM Same formula. Bigger bottle. Better price. Major Robafen DM delivers the same relief as Robitussin® DM—at twice the size of the standard 4 oz bottle. Each 20 mL dose...
  • Rugby Simethicone 180mg - 60 Softgels | Ultra Strength Phazyme (5 Pack) Rugby Simethicone 180 mg with Highlights - 5 Pack

    Rugby Simethicone 180 mg - 60 Softgels | Ultra Strength Phazyme (5 Pack)

    Rugby Laboratories
    $21.99
    Rugby Simethicone 180 mg – 60 Softgels | Ultra Strength Phazyme (5 Pack) Rugby Simethicone 180 mg delivers fast relief from gas, bloating, abdominal pressure, and discomfort. This 5 pack includes five bottles of 60 softgels each — 300 total...
  • Main product image showing 24 bottles of Major Nasal Decongestant Spray 0.05% – Compare to Afrin Major Nasal Decongestant Spray New Box - Oxymetazoline 0.05% Afrin Equivalent

    Major Nasal Decongestant Spray - 1 fl oz | Compare to Afrin No Drip (24 Pack)

    Major Pharmaceuticals
    $82.99
    Major Nasal Decongestant Spray Oxymetazoline 0.05% – 1 fl oz | Compare to Afrin® (24 Pack) Compare to the active ingredient in Afrin® No Drip This 24-pack delivers powerful, pharmacy-grade nasal congestion relief at an exceptional bulk...
  • Rugby Daily-Vite Multivitamin - 5 Pack Rugby Daily-Vite Multivitamin 500 Tablets

    Rugby Daily-Vite Multivitamin - 100 Tablets | One A Day Essential (5 Pack)

    Rugby Laboratories
    $21.99
    Rugby Daily-Vite Multivitamin – 500 Tablets (5 Pack) | Compare to One A Day Essentials Rugby Daily-Vite Multivitamin – 5 Pack delivers complete daily nutrition comparable to One A Day® Essentials at the best bulk value online. Each...

Over-the-counter (OTC) medications are non-prescription drugs that can be purchased without a prescription. These medications are intended to provide relief from common ailments and mild health conditions.