Best Cold Medicine Without Dextromethorphan (No DM)
Table of Contents
- ONCOR Liquid Guaifenesin – No DM, Sugar, Alcohol, or Menthol
- Rugby Mucus & Chest Congestion Guaifenesin 200 mg Cough Syrup
- Foster & Thrive Adult Tussin Guaifenesin 200 mg Cough Syrup
- Rugby Chest Congestion Relief Guaifenesin Oral Solution – 16 oz
- Guaifenesin Tablets – Rugby & Major
- Why Avoid Dextromethorphan (DM)?
- When to Use Guaifenesin-Only Cold Medicine
- Cold Medicine Without Dextromethorphan: Conclusion
- Cold Medicine Without Dextromethorphan: Products Mentioned
- About xeteor.com
- FAQs
Looking for cold medicine without dextromethorphan (DM)? You’re not alone. Many people want to avoid DM due to side effects like drowsiness, drug interactions, or simply because they prefer a more targeted solution like guaifenesin. While guaifenesin-only tablets are easy to find, liquid cough syrups without dextromethorphan are much harder to come by.
Below, we break down the best DM-free cold medicines available today — starting with ONCOR Liquid Guaifenesin, a sugar-free, alcohol-free, and menthol-free syrup available exclusively at xeteor.com.
ONCOR Liquid Guaifenesin – No DM, Sugar, Alcohol, or Menthol
If you’re looking for a cold medicine without dextromethorphan that’s also sugar-free, alcohol-free, and menthol-free, ONCOR Liquid Guaifenesin 100 mg / 5 mL is your best option. It’s a guaifenesin-only expectorant designed for people with ingredient sensitivities who still want effective relief from chest congestion.
Manufactured by ONCOR Pharmaceuticals in Elkridge, Maryland, this product is exclusively available at xeteor.com. It comes in a 16 oz bottle and is priced competitively.
Also available in: 3-pack | 12-pack
- Free of: Dextromethorphan (DM), sugar, alcohol, and menthol
- Flavor: Smooth cherry
- Active Ingredient: Guaifenesin 100 mg per 5 mL
- Availability: Single bottle or multi-pack with free shipping
Why it matters: While other guaifenesin cough syrups may be free of one or two common additives, ONCOR is one of the only liquid cold medicines that eliminates all three—without compromising on effectiveness.
Rugby Mucus & Chest Congestion Guaifenesin 200 mg Cough Syrup
Back in stock as of October 6, 2024, Rugby’s guaifenesin-only cherry cough syrup is identical to Major Robafen Congestion Formula. It’s a favorite for those who prefer a higher guaifenesin dose (200 mg).
Also available in: 3-pack
- Active Ingredient: Guaifenesin USP 200 mg
- Includes: Menthol, high fructose corn syrup
- Note: Not suitable for those avoiding menthol or sugar
Foster & Thrive Adult Tussin Guaifenesin 200 mg Cough Syrup
Produced by McKesson, Foster & Thrive is a new brand offering a clean guaifenesin syrup similar to Rugby’s formula — but without propylene glycol.
- Active Ingredient: Guaifenesin 200 mg
- Contains: Menthol and high fructose corn syrup
- Note: Great alternative if you can't find Rugby or Major
Rugby Chest Congestion Relief Guaifenesin Oral Solution – 16 oz
This is Rugby’s guaifenesin 100 mg per 5 mL syrup, available in a large 16 oz bottle. It's a reliable cold medicine without dextromethorphan and cost-effective alternative but does contain menthol and artificial sweeteners.
Also available in: 3-pack | 4-pack
- Active Ingredient: Guaifenesin 100 mg
- Contains: Menthol, FD&C Red #40, sucralose, parabens
Guaifenesin Tablets – Rugby & Major
If you prefer tablets, both Major and Rugby offer guaifenesin-only options without DM. These are simple and effective, especially for travel or those who dislike syrup textures.
Major Guaifenesin 200 mg – 100 Tablets
Also available in: 2-pack
- Active Ingredient: Guaifenesin 200 mg
- Form: Immediate-release tablets
Rugby Guaifenesin 400 mg – 60 Tablets
Also available in: 3-pack
- Active Ingredient: Guaifenesin 400 mg
- Form: Immediate-release tablets
Why Avoid Dextromethorphan (DM)?
Some people avoid DM due to possible side effects or drug interactions. DM can cause drowsiness, dizziness, or nausea and can interact with MAO inhibitors, SSRIs, and tricyclic antidepressants. It also suppresses the cough reflex without addressing underlying mucus production.
Guaifenesin, on the other hand, thins and loosens mucus, making coughs more productive and addressing the root cause of congestion.
When to Use Guaifenesin-Only Cold Medicine
Guaifenesin works best for wet, productive coughs with mucus and chest congestion. It’s ideal for:
- Common colds and mild bronchitis
- Sinus drainage and post-nasal drip
- Phlegm-heavy coughs
Always read the label to confirm that the product is DM-free and contains guaifenesin as the only active ingredient.
Cold Medicine Without Dextromethorphan: Conclusion
If you're trying to avoid dextromethorphan, there are excellent cold medicine alternatives that use guaifenesin only. For a sugar-free, alcohol-free, menthol-free solution, ONCOR Liquid Guaifenesin is your best bet — and it’s only available at xeteor.com. Other reliable options include products from Rugby, Foster & Thrive, and Major. Compare ingredients and choose what fits your health needs best.
For a broader comparison, including cough syrups that contain dextromethorphan (DM) or phenylephrine (PE), see our full list of Major and Rugby cold medicine options here.
Cold Medicine Without Dextromethorphan: Products Mentioned
Oncor Guaifenesin 100 mg / 5 mL Expectorant Cough Syrup - 16 fl oz | Robitussin
$12.99
Oncor Guaifenesin Liquid – 100 mg per 5 mL (16 fl oz) | Sugar-Free Chest Congestion Relief Oncor Guaifenesin Liquid is a smooth cherry-flavored expectorant...… read more
Oncor Guaifenesin 100 mg Cough Syrup - 16 fl oz | Robitussin (3 Pack)
$22.98
Oncor Liquid Guaifenesin – 100 mg per 5 mL (16 fl oz Each, 3 Pack) | No DM, No Menthol, Sugar-Free Oncor Liquid Guaifenesin is...… read more
Oncor Liquid Guaifenesin 100 mg/5 mL – 16 oz (12 Pack) | No DM | Chest Congestion Relief
$69.96
Oncor Liquid Guaifenesin – 12 Pack (16 fl oz Bottles) | No DM, No Menthol, Just Pure Expectorant Get clean, powerful congestion relief — without...… read more
Rugby Mucus & Chest Congestion Liquid Guaifenesin 200 mg Cherry Flavor - 4 fl oz
$6.99
Rugby Mucus & Chest Congestion Liquid Guaifenesin 200 mg Cherry Flavor - 4 Fl Oz Guaifenesin, USP 200 mg per 10 mL Expectorant Cherry Flavored...… read more
Rugby Mucus & Chest Congestion Liquid Guaifenesin 200 mg Cherry Flavor - 4 fl oz | Robitussin (3 Pack)
$17.97
Rugby Mucus & Chest Congestion Liquid Guaifenesin 200 mg Cherry Flavor - 4 Fl Oz | Robitussin Mucus + Chest Congestion (3 Pack) What will...… read more
Foster & Thrive Adult Tussin Guaifenesin 200 mg Expectorant Cough Syrup - 4 fl oz | Robitussin
$9.99
Foster & Thrive Adult Tussin Guaifenesin 200 mg Expectorant Syrup - 4 fl oz | Robitussin Mucus + Chest Congestion Foster & Thrive, a McKesson's...… read more
Rugby Chest Congestion Relief Guaifenesin Oral Solution Cherry Flavor - 16 Fl Oz | Robitussin
$12.99
Helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive. Rugby Chest Congestion Relief Guaifenesin Oral Solution Cherry Flavor - 16 Fl...… read more
Rugby Chest Congestion Relief Guaifenesin 100mg | Robitussin (3 Pack)
$29.97
Rugby Chest Congestion Relief Guaifenesin 100mg Cough Syrup - 16 fl oz | Robitussin (3 Pack) Cherry Menthol - Is That Even a Real Flavor?...… read more
Rugby Chest Congestion Relief Guaifenesin 100mg Cough Syrup | Robitussin (4 Pack)
$39.96
Rugby Chest Congestion Relief Guaifenesin 100mg Cough Syrup - 16 fl oz | Robitussin (4 Pack) Cherry Menthol - Is That Even a Real Flavor?...… read more
Major Guaifenesin 200 mg - 100 Tablets | Mucinex
$8.99
Major Immediate Release Guaifenesin 200 mg - 100 Tablets | Mucinex Key Features Works like Mucinex Guaifenesin 200 mg Expectorant 100 immediate release tablets Expiration...… read more
Major Guaifenesin 200 mg - 100 Tablets | Mucinex (2 Pack)
$12.98
Major Guaifenesin 200 mg - 100 Tablets - Immediate Release, No Dextromethorphan | Mucinex (2 Pack)What will I receive?2 bottles of Major Guaifenesin 200 mg...… read more
Rugby Chest Congestion Relief Guaifenesin 400 mg - 60 Tablets | Mucinex
$7.99
Rugby Chest Congestion Relief - 60 Tablets | Dye-Free Mucinex Key Features Works like Mucinex SE Guaifenesin, 400 mg Dye-Free Expectorant 60 immediate release tablets...… read more
Rugby Chest Congestion Relief Guaifenesin 400 mg - 60 Tablets | Mucinex (3 Pack)
$15.99
Rugby Chest Congestion Relief Guaifenesin 400 mg - 60 Tablets | Dye-Free Mucinex SE (3 Pack) What will I receive? 3 bottles of Rugby Chest...… read more
About xeteor.com
xeteor.com, started in 2018 is based in Las Vegas, Nevada and is online pharmacy focusing on discount over-the-counter generic medications, like cold medicine without dextromethorphan and diabetic test strips. We find deals normally reserved for "big pharma" and offer them to the consumer at discount prices. Ranking as the #1 authorized online reseller of Major Pharmaceuticals, Rugby Laboratories and ONCOR Pharmaceuticals products according to Trustpilot.com, xeteor.com has 8,000+ 5-star reviews online, including Amazon, eBay, Trustpilot, and Google. xeteor.com is a Google Top Quality Store, earned by merchants that provide a great shopping experience.
Shipping Time & Cost
All items ship same day when purchased by 3 pm PST Monday - Friday. We offer free shipping nationwide on orders over $30 and all savings packs. Shipping times are between 3 to 8 business days, with an average of 3.3 business days. A link to our full shipping policy is here.
Payment Options
We offer multiple convenient payment options, including Visa, Mastercard, Discover, American Express, Google Pay, Apple Pay, PayPal and Venmo.
Return Policy
We offer a 100% satisfaction guarantee. If you are not satisfied with the product, you may return it up to 100 days from the date of purchase. We offer free return shipping to ensure you can try the product risk free. A link to our full return policy is here.
How to Reach Us?
If you have questions about the product or need assistance, we are happy to talk on the phone. Call us at 1-833-787-4777 between 9 am - 5 pm PST Monday - Friday. You can also email us at [email protected] or text us at 702-659-7022. A link to our full contact us page is here.
Disclaimer: This post is intended for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or another qualified health provider with any questions you may have regarding a medical condition or before starting any new treatment. Do not disregard professional medical advice or delay in seeking it because of something you have read in this post.
FAQs
What is the best cold medicine without dextromethorphan (DM)?
The best option depends on your needs, but ONCOR Liquid Guaifenesin 100 mg / 5 mL is one of the few cough syrups that contains no DM, no sugar, no alcohol, and no menthol. It's available exclusively at xeteor.com.
Why should I avoid dextromethorphan (DM)?
Some people avoid DM because it can cause drowsiness, dizziness, or nausea and may interact with certain antidepressants or MAO inhibitors. Others prefer not to suppress their cough and instead target mucus with guaifenesin.
What does guaifenesin do for a cough?
Guaifenesin is an expectorant. It thins mucus in the airways, making it easier to cough up. This helps relieve chest congestion and promotes a more productive, less irritating cough.
Which guaifenesin syrup has the cleanest ingredient list?
ONCOR Liquid Guaifenesin stands out for being free of dextromethorphan, sugar, alcohol, and menthol — a rare combination that makes it ideal for sensitive users.
Can I take guaifenesin if I’m diabetic or avoiding sugar?
Yes — sugar-free versions like ONCOR Liquid Guaifenesin are available. Always check the inactive ingredients and consult your doctor if you have concerns.
Are guaifenesin tablets as effective as syrups?
Yes — tablets such as those from Major or Rugby provide the same active ingredient and work just as well. Syrups are typically preferred for faster onset or for people who have trouble swallowing pills.
