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Over-The-Counter


Affordable Over-the-Counter Medicines Without the Brand-Name Price

Looking for low-cost relief without sacrificing quality? Our over-the-counter selection includes trusted generics that compare to top brands like Mucinex®, Colace®, Robitussin®, Citrucel®, and Phazyme®—all at everyday low prices.

From stool softeners like Docusate Sodium to guaifenesin cough syrups without dextromethorphan, we stock remedies for constipation, cough and cold, indigestion, hemorrhoids, and more. Many of our products are made by trusted manufacturers such as Foster & Thrive®, Rugby®, Major®, and Perrigo®.

  • Constipation Relief: Docusate Sodium, Bisacodyl, PEG 3350
  • Cough & Cold: Robafen DM, Liquid Guaifenesin, Mucus Relief
  • Pain Relief: Capsaicin Cream, Lidocaine Patches, Menthol Rubs
  • Allergies: Diphenhydramine, Cetirizine, Chlorpheniramine
  • Digestive Support: Simethicone, Methylcellulose, Antacids

Need help finding something? Check out our blog or contact us for personalized assistance. We offer fast shipping and discounts on bulk packs for caregivers, clinics, and families stocking up.

What ailment can we help you with today?


⭐ Top Over-the-Counter Deals

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  • Major Fiber Powder Therapy Methylcellulose Orange Flavor - 16oz (Citrucel) Major Fiber Therapy Powder Helps Relieve Stool Irregularity

    Major Fiber Therapy Methylcellulose Powder – 16 oz | Compare to Citrucel

    Major Pharmaceuticals
    $13.99
    Major Fiber Therapy Powder – Methylcellulose 16 oz Orange Flavor | Compare to Citrucel® This is the direct generic replacement for the original Citrucel® Powder with Sugar, which has been permanently discontinued by the manufacturer. It...
  • Rugby Sodium Chloride Hypertonicity Opthalmic Ointment, 5% - 3.5 g | Muro 128 Ointment Rugby Sodium Chloride 5% Ointment Amazon

    Rugby Sodium Chloride Hypertonicity Ophthalmic Ointment 5% | Muro 128

    Rugby Laboratories
    $14.99
    Rugby Sodium Chloride Ophthalmic Ointment 5% – 3.5g Tube | Compare to Muro 128® Need overnight relief from corneal swelling? Rugby Sodium Chloride Ophthalmic Ointment 5% is a sterile, preservative-free eye ointment used for the temporary relief...
  • Perrigo Cetirizine 10mg - 300 Tablets (Zyrtec) Padagis Cetirizine 10mg - 300 Tablets (Zyrtec)  Benefits

    Perrigo Cetirizine Hydrochloride 10 mg - 300 Tablets | Zyrtec

    Perrigo
    $13.99
    Cetirizine Hydrochloride 10 mg Tablets – 300 Count | Generic Zyrtec® by Perrigo Save on allergy relief with this trusted Zyrtec® generic. Perrigo Cetirizine Hydrochloride 10 mg delivers the same FDA-approved active ingredient as brand-name...
  • 5 pack of Major Nasal Decongestant Spray 1 fl oz bottles – generic Afrin pump spray for congestion relief Promotional image of Major Nasal Decongestant Spray 5 Pack – shows free shipping, made in USA, compares to Afrin, and highlights 5 fl oz total for sinus and nasal congestion relief

    Major Nasal Decongestant Spray - 1 fl oz | Compare to Afrin No Drip (5 Pack)

    Major Pharmaceuticals
    $18.95
    Major Nasal Decongestant Spray – 1 fl oz (5 Pack) | Compare to Afrin® No Drip Powerful, non-drowsy nasal relief—without the brand-name markup. This 5-pack of Major 12 Hour Nasal Decongestant Spray contains Oxymetazoline HCl 0.05%, the...
  • Rugby Senna Leaf Extract Syrup 176mg/5mL Dietary Supplement - 8 Fl Oz Rugby Senna Leaf Extract Syrup 176mg/5mL Dietary Supplement - 8 Fl Oz is chocolate flavored

    Rugby Senna Syrup 8 fl oz – 176 mg/5 mL for Constipation Relief

    Rugby Laboratories
    $12.95
    Rugby Senna Syrup – 8 fl oz | Senna Leaf Extract 176 mg/5 mL | Chocolate Flavor Rugby Senna Syrup provides effective overnight relief from occasional constipation. Each teaspoon contains 176 mg of senna leaf extract (as sennosides), a stimulant...
  • Rugby Chest Congestion Relief Guaifenesin Oral Solution - 16 Fl Oz Bottle Rugby Chest Congestion Relief Guaifenesin Oral Solution - 16 Fl Oz Cherry Menthol Flavor

    Rugby Chest Congestion Relief Guaifenesin 100 mg Cough Syrup - 16 fl oz | Compare to Robitussin

    Rugby Laboratories
    $12.99
    Rugby Chest Congestion Relief Guaifenesin 100 mg Cough Syrup – 16 fl oz | Compare to Robitussin Clear chest congestion without the high price tag. Rugby Chest Congestion Relief delivers 100 mg of guaifenesin per 5 mL in a full 16 fl oz...
  • Major Simethicone 80 mg - 100 Chewable Tablets | Mint Flavor (3 Pack) Major Simethicone 80 mg Chewable Tablets – Mint Flavor – 3 Pack – Antiflatulent for Gas, Bloating, and Discomfort

    Major Simethicone 80 mg - 100 Chewable Tablets | Mint Flavor (3 Pack)

    Major Pharmaceuticals
    $18.99
    Major Simethicone 80 mg – 100 Chewable Mint Flavor Tablets (3 Pack) | Relief from Gas, Pressure & Bloating Fast-acting gas relief in a chewable mint tablet. Major Simethicone 80 mg helps reduce uncomfortable bloating, pressure, and fullness...
  • Major FeroSul 325 mg Ferrous Sulfate Iron Supplement | FeoSol - 1000 Red Tablets Major FeroSul 325 mg Ferrous Sulfate Iron Supplement FeoSol - 1000 Red Tablets - Easy to Swallow Tablets

    Major FeroSul Ferrous Sulfate 325 mg - 1000 Tablets | Feosol

    Major Pharmaceuticals
    $15.99
    Major FeroSul Ferrous Sulfate 325 mg – 1000 Tablets | Compare to Feosol® Major FeroSul Ferrous Sulfate is a widely used iron supplement for the treatment and prevention of iron deficiency anemia. Each coated tablet delivers 65 mg of elemental...
  • Major CertaVite with Antioxidants Vitamin and Mineral Supplement - 300 Tablets New White Bottle Bottle of Major CertaVite multivitamins on a white counter next to a small green plant and a rolled-up yoga mat.

    Major CertaVite with Antioxidants Multivitamin - 300 Tablets | Theragran-M

    Major Pharmaceuticals
    $19.99
    Major CertaVite with Antioxidants – 300 Tablets | Original Theragran-M® Generic Compare to the original Theragran-M® with iron — a complete daily multivitamin + mineral for adults. Major CertaVite with Antioxidants is the go-to U.S...
  • Major Bismuth Subsalicylate - 30 Tablets | Pepto-Bismol (6 Pack) Major Bismuth Subsalicylate - 30 Tablets | Pepto-Bismol (6 Pack)

    Major Bismuth Subsalicylate - 30 Tablets | Pepto-Bismol (6 Pack)

    Major Pharmaceuticals
    $18.96
    Major Bismuth Subsalicylate 262 mg – 30 Chewable Tablets (6 Pack) | Generic Pepto-Bismol® Alternative Major® Bismuth Subsalicylate Chewable Tablets provide the same trusted active ingredient as Pepto-Bismol® to relieve diarrhea,...
  • Major Adults Extra Strength Acetaminophen 500 mg - 1000 Caplets (Tylenol) Major Adults Extra Strength Acetaminophen 500 mg - 1000 Caplets (Tylenol) - Full Drug Facts Label

    Major Acetaminophen 500 mg - 500 Caplets | Extra Strength Tylenol

    Major Pharmaceuticals
    $14.99
    Major Extra Strength Acetaminophen 500 mg – 500 Caplets | Generic Tylenol Alternative Looking for a reliable Generic Tylenol option in bulk? This 500-count bottle of Major Extra Strength Acetaminophen 500 mg caplets delivers the same active...
  • Major Original Nasal Decongestant Spray 12 Hour Relief Oxymetazoline - 0.5 fl oz | Afrin Original Nasal Spray - 5 Pack Major Nasal Decongestant Spray - 0.5 fl oz | Compare to Afrin Original (5 Pack)

    Major Nasal Decongestant Spray - 0.5 fl oz | Compare to Afrin Original (5 Pack)

    Major Pharmaceuticals
    $17.99
    Major Maximum Strength Nasal Decongestant Spray – 0.5 fl oz | 12 Hour Relief (5 Pack) Major Maximum Strength Nasal Decongestant Spray – 0.5 fl oz (5 Pack) provides fast, long-lasting relief from nasal congestion due to colds, allergies, and...
  • Rugby Capsaicin Cream - 3 Pack Rugby Capsaicin Cream - Zostrix Generic - 3 Pack

    Rugby Capsaicin Cream 0.025% - 2 oz | Zostrix (3 Pack)

    Rugby Laboratories
    $17.99
    Rugby Capsaicin Cream 0.025% – 3 Pack (2 oz Each) | Zostrix® Generic for Nerve & Joint Pain Zostrix vs Rugby Capsaicin Cream is one of the most common searches for affordable topical pain relief. Rugby Capsaicin Cream 0.025% uses the same...
  • Rugby Zinc Sulfate 220 mg Dietary Supplement - 100 Tablets - 4 Pack Rugby Zinc Sulfate 220 mg - 100 Tablets - 4 Pack

    Rugby Zinc Sulfate 220 mg - 100 Tablets (4 Pack)

    Rugby Laboratories
    $17.96
    Rugby Zinc Sulfate 220 mg Dietary Supplement – 100 Tablets – 4 Pack Rugby Zinc Sulfate 220 mg delivers 50 mg of elemental zinc per tablet to help support immune function, skin healing, and overall wellness. This 4-pack contains 400 tablets...
  • Rugby Budesonide Nasal Allergy Spray 32 mcg - 120 Metered Sprays (Rhinocort) Rugby Budesonide Nasal Allergy Spray 32 mcg - 120 Metered Sprays (Rhinocort) Bottle

    Rugby Budesonide Nasal Allergy Spray 32 mcg - 120 Sprays | Rhinocort

    Rugby Laboratories
    $12.99
    Breathe Easier with Budesonide Nasal Spray Budesonide nasal spray delivers fast relief from congestion and sinus pressure. The active ingredient budesonide reduces inflammation and opens nasal passages within hours, providing 12 hours of clearer...
  • Rugby Maximum Strength Pain Relieving Cream | Thera-Gesic (3 Pack) Rugby Maximum Strength Pain Relieving Cream - 3 Pack

    Rugby Pain Relieving Cream – 3 oz | Compare to Thera-Gesic (3 Pack)

    Rugby Laboratories
    $19.99
    Rugby Pain Relieving Cream – 3 oz | Compare to Thera-Gesic (3 Pack) Looking to stock up and save? This 3-pack of Rugby Pain Relieving Cream is ideal for daily relief from arthritis, sore muscles, and back pain. Each 3 oz tube features the proven...
  • Front label of Rugby Dextromethorphan HBr 15 mg 5-pack softgel bottles Smiling woman holding softgel capsule for non-drowsy cough relief

    Rugby Dextromethorphan HBr 15mg - 20 Softgels | Robitussin (5 Pack)

    Rugby Laboratories
    $19.99
    Rugby Dextromethorphan HBr 15 mg Softgels – 5 Pack (100 Softgels Total) | Non-Drowsy Cough Suppressant Reliable, non-drowsy relief for dry, persistent coughs. Each Rugby softgel contains Dextromethorphan Hydrobromide 15 mg, the same active...
  • Rugby Arthritis Pain Relieving Cream - 3 Pack Rugby Arthritis Pain Relieving Cream Capsaicin 0.075% - 3 Pack

    Rugby Arthritis Pain Relieving Cream - 2 oz | Zostrix HP (3 Pack)

    Rugby Laboratories
    $19.99
    Rugby Capsaicin Cream 0.075% – 2 oz (3 Pack) | Strong Zostrix HP® Alternative Need powerful pain relief for arthritis or nerve pain? This 3-pack of Rugby Capsaicin Cream 0.075% contains the same active ingredient as Zostrix HP® — a...
  • Rugby Daily-Vite Multivitamin - 5 Pack Rugby Daily-Vite Multivitamin 500 Tablets

    Rugby Daily-Vite Multivitamin - 100 Tablets | One A Day Essential (5 Pack)

    Rugby Laboratories
    $18.95
    Rugby Daily-Vite Multivitamin – 500 Tablets (5 Pack) | Compare to One A Day Essentials Rugby Daily-Vite Multivitamin – 5 Pack delivers complete daily nutrition comparable to One A Day® Essentials at the best bulk value online. Each...
  • Rugby Chest Congestion Relief PE Sinus Expectorant Nasal Decongestant - 60 Immediate Release Tablets | Mucinex (3 Pack) Rugby Chest Congestion Relief PE Sinus Expectorant Nasal Decongestant - 60 Immediate Release Tablets | Mucinex (3 Pack)

    Rugby Chest Congestion Relief PE – 60 Tablets | Compare to Mucinex Sinus-Max (3 Pack)

    Rugby Laboratories
    $18.99
    Rugby Chest Congestion Relief PE – 3 Pack (180 Tablets) | Compare to Mucinex Sinus-Max® Find powerful relief from chest and nasal congestion with Rugby Chest Congestion Relief PE. This 3-pack bundle offers 180 tablets of an effective,...
  • Rugby Meclizine 12.5 mg - 1000 Caplets

    Rugby Meclizine 12.5 mg - 1000 Caplets | Bonine

    Rugby Laboratories
    $13.99
    Prevents and treats nausea, vomiting or dizziness due to motion sickness. Rugby Meclizine 12.5 mg - 1000 Caplets Meclizine HCL, USP 12.5 mg each (antiemetic)  1000 Caplets Antiemetic Expiration Date: 12-2024 Ingredients Active...
  • Rugby Vitamin D3 50 mcg (2000 IU) - 100 Tablets | Gluten Free (2 Pack) Rugby Vitamin D3 50 mcg (2000 IU) - buy at xeteor.com

    Rugby Vitamin D3 50 mcg (2000 IU) - 100 Tablets | Gluten Free (2 Pack)

    Rugby Laboratories
    $13.99
    Rugby Vitamin D3 50 mcg (2000 IU) – 100 Tablets (2 Pack) | Bone, Immune & Mood Support High-potency vitamin D3 for everyday wellness. Rugby Vitamin D3 provides 2,000 IU of cholecalciferol per tablet to help support bone strength, immunity, and...
  • Major Ibuprofen 200 mg - 1000 Tablets (Advil) Major Ibuprofen 200 mg - 1000 Tablets (Advil) Drug Facts

    Major Ibuprofen 200 mg - 1000 Tablets | Advil

    Major Pharmaceuticals
    $17.49
    Major Ibuprofen 200 mg - 1000 Tablets | Advil Expiration Date: 7-2026 Active Ingredient Ibuprofen 200 mg (NSAID) - Pain reliever/Fever reducer Equivalent To Advil Uses Temporarily relieves minor aches and pains due to Headache Muscular aches Minor...
  • Rugby Therems Multivitamin - 130 Tablets | Theragran (3 Pack) Rugby Therems Multivitamin with Highlights - 3 Pack

    Rugby Therems Multivitamin - 130 Tablets | Theragran (3 Pack)

    Rugby Laboratories
    $17.97
    Rugby Therems Multivitamin Supplement – 3 Pack (390 Tablets) | Compare to Theragran Rugby Therems Multivitamin – 3 Pack (390 Tablets) is a daily vitamin-only formula that supports energy, immune function, and overall wellness. Designed as a...
  • Biofreeze Pain Relief Gel Tube - 4 fl oz Product Photo  Biofreeze Pain Relief Gel Tube - 4 fl oz Graphic

    Biofreeze Pain Relief Gel - 4 fl oz

    Biofreeze
    $12.99
    Biofreeze Professional Pain Relief Gel, Menthol 5% – 4 fl oz | Cooling Pain Relief Clinically trusted cold therapy for sore muscles and joints. Biofreeze® Professional Pain Relief Gel uses Menthol 5% to deliver fast, cooling relief that...
  • Rugby Diclofenac Sodium Topical Gel 1% - 3.53 oz (Voltaren) Rugby Diclofenac Sodium Topical Gel - Generic Alternative to Voltaren

    Rugby Diclofenac Sodium Gel 1% - 3.53 oz | Voltaren

    Rugby Laboratories
    $14.99
    Rugby Diclofenac Sodium Topical Gel 1% – 3.53 oz | Voltaren Generic Compare to Voltaren Arthritis Pain Gel. This over-the-counter 1% NSAID gel provides the same active ingredient as Voltaren — diclofenac sodium — at a fraction of the...
  • Major Docusate Sodium 250 mg - Free Shipping Major Docusate Sodium 250 mg with Highlights - 2 Pack

    Major Docusate Sodium 250 mg - 100 Softgels | Extra Strength Colace (2 Pack)

    Major Pharmaceuticals
    $15.99
    Major Extra Strength Docusate Sodium 250 mg – 200 Softgels (2 Pack) | Compare to Colace® Stock up and save with this 2-pack of Major Docusate Sodium 250 mg. You'll receive 200 softgels total, providing a cost-effective supply of gentle stool...
  • Major Guaifenesin 200 mg - 100 Tablets | Mucinex (2 Pack) Guaifenesin 200 mg with Highlights - 2 Pack

    Major Guaifenesin 200 mg - 100 Tablets | Mucinex (2 Pack)

    Major Pharmaceuticals
    $13.99
    Major Guaifenesin 200 mg – 100 Tablets (2 Pack) | Compare to Mucinex® Relieve chest congestion with Major Guaifenesin 200 mg tablets. This immediate-release expectorant helps thin and loosen mucus, making coughs more productive and clearing...
  • Major Aspirin Low Dose 81 mg - 1000 Tablets (Bayer Low Dose Aspirin) Major Aspirin Low Dose 81 mg - 1000 Tablets | Bayer Low Dose Aspirin
    Sale 69%
    Sale 69%

    Major Aspirin Low Dose 81 mg - 1000 Tablets | Bayer Low Dose Aspirin

    Major Pharmaceuticals
    $47.60
    $14.99
    Major Low Dose Aspirin 81 mg - 1000 Tablets | Bayer Low Dose Aspirin Compare to the active ingredient in Bayer Low Dose Aspirin Non-steroidal anti-inflammatory drug  Pain Reliever (NSAID) Enteric & safety coated 1000 Tablets EXPIRATION...
  • Rugby Niacin 1000 mg Timed Release - 100 Captabs | Gluten Free (2 Pack) Rugby Niacin 1000 mg Timed Release - 100 Captabs | Gluten Free (2 Pack)

    Rugby Niacin 1000 mg Timed Release - 100 Captabs | Gluten Free (2 Pack)

    Rugby Laboratories
    $19.99
    Rugby Niacin 1000 mg – Timed Release | 2 Pack (100 Captabs Each) Double the supply of pharmacy-grade, high-potency Vitamin B3 to support healthy cholesterol, metabolism, and cardiovascular function—without the Amazon price tag. This 2-pack of...
  • Four bottles of Rugby Sea-Omega Fish Oil 1000 mg showing product labels and packaging Rugby Sea-Omega Fish Oil 4 pack deal highlighting brain and heart health benefits

    Rugby Sea-Omega Fish Oil 1000 mg - 50 Softgels (4 Pack)

    Rugby Laboratories
    $15.96
    Sea-Omega by Rugby – 1000 mg Fish Oil / 600 mg Omega-3 – 4 Pack | Gluten-Free, Made in USA Support heart, brain, and joint health with Sea-Omega 1000 mg, a high-potency omega-3 supplement made with purified fish oil. Each softgel delivers 300...

Over-the-counter (OTC) medications are non-prescription drugs that can be purchased without a prescription. These medications are intended to provide relief from common ailments and mild health conditions.