Capsaicin & Zostrix Cream Alternatives

Capsaicin (Zostrix)

Capsaicin Creams – Zostrix® Alternatives for Pain Relief

If you're searching for affordable, effective relief from nerve pain, arthritis, or shingles, our capsaicin cream selection delivers the same strength and active ingredients as Zostrix®—without the high price tag. We carry Rugby brand capsaicin creams in 0.025% and 0.075% strengths, trusted by thousands of customers across the U.S.

Capsaicin works by blocking pain signals from the nerves, providing targeted relief with continued use. Whether you’re looking for a low-cost Zostrix® alternative or comparing formulas with menthol or lidocaine, we’ve got options that ship fast—and come with free shipping on multi-packs.

Not sure which strength or product is right for you? Read our Zostrix® comparison blog or explore our capsaicin guide for neuropathy and arthritis.

Looking for affordable pain relief? These capsaicin creams are trusted by thousands of customers dealing with arthritis, nerve pain, or shingles. Compare prices, strengths, and shipping options below.

Top-Rated Capsaicin Creams You Can Trust

Sort By:

Per Page:

Filters

Quick view

Rugby Capsaicin Cream 0.025% - 2 oz | Zostrix (24 Pack)

Rugby

$99.84

Rugby Capsaicin Cream 0.025% – 2 oz (24 Pack) | Best Bulk Value Only $99.84 for 24 tubes – just $4.16 each with FREE shipping! Need lasting relief at the lowest price per tube? This bulk 24-pack of Rugby Capsaicin Cream 0.025% delivers...

Quantity:

Add to Cart

Frequently Asked Questions About Capsaicin & Zostrix Cream

What is the difference between Zostrix and capsaicin cream?

Zostrix is a brand name cream that contains capsaicin 0.025%—the same active ingredient found in affordable generics like Rugby Capsaicin Cream. You get the same strength and relief, but without paying for the name.

Which strength of capsaicin cream is right for me?

The 0.025% strength is ideal for daily relief from nerve pain, arthritis, and minor joint discomfort. If you're dealing with more intense pain, higher-strength versions like 0.075% may offer better results—but they may also cause stronger burning sensations.

Is capsaicin cream good for shingles nerve pain?

Yes. Capsaicin cream is often used to relieve the tingling and burning of postherpetic neuralgia (shingles-related nerve pain). Always test on a small area first, and apply regularly for the best results.

How often should I apply capsaicin cream?

Apply 3 to 4 times daily unless directed otherwise. Capsaicin needs consistent use to build up effectiveness—relief may improve after several days of regular use.