With Citrucel Powder now officially discontinued, Major Fiber Therapy Methylcellulose Powder has emerged as the go-to generic replacement. While it contains the same active ingredient and performs just like the brand name, not all generics taste or dissolve exactly alike. In this post, we’ll explore the top concerns discussed in Major Fiber Therapy reviews to help you know what to expect.

We take a look at Major Fiber Therapy reviews as well as feedback we've received from customers to summarize the top questions and issues with Major Fiber Therapy so you can make a more informed decision on whether Major Fiber Therapy is right for you. In addition, we provide tips to avoid some of the issues outlined in the reviews below.

Top Questions - Major Fiber Therapy Methylcellulose Powder

You can view questions on our website, below the product image and star ratings by clicking on the " Questions" tab.

1. Is Major Fiber Therapy sugar free?

No, it is not. Major Fiber Therapy contains sucrose in the inactive ingredients. There is currently no sugar-free version of Major Fiber Therapy. You can view all the active and inactive ingredients at the end of this blog post.

2. Where is Major Fiber Therapy made?

Major Fiber Therapy is manufactured in the USA. We confirmed this information with Major Pharmaceuticals. If you have product questions, you can contact them directly at 1-800-616-2471.  You can also contact us at 1-833-787-4777 (9 am to 5 pm PST).

3. What does Major Fiber Therapy taste like?

Most customers have reported Major Fiber Therapy has a mild orange taste. One customer described the taste as sweet and liked it more than the brand name Citrucel. 

4.  Is Major Fiber Therapy gluten-free?

Major Fiber Therapy is explicitly labeled as GLUTEN-FREE on the jar. Methylcellulose is generally considered gluten-free. It is a synthetic compound derived from cellulose, which is plant-based. Methylcellulose is used in a variety of food and pharmaceutical products as a thickener, stabilizer, or emulsifier. It is not derived from wheat, barley, rye, or any other gluten-containing grains, so it is typically safe for individuals with celiac disease or gluten sensitivity.

5.  How many servings are in one jar of Major Fiber Therapy?

There is 16 oz or 454 g of powder in one jar of Major Fiber Therapy. The instructions say for adults to take one rounded tablespoon (19 g) in 8 ounces of water fluid up to 3 times daily at the first sign of constipation or irregularity. 

The total servings in one jar is ~24 servings (454 g ÷ 19 g) for adults.  If you were to take Major Fiber once per day, a single jar would last you 24 days.  If you were to take the maximum recommended dose three times per day, a single jar would last you 8 days.

Top Concerns about Major Fiber Therapy

Below are the top 3 concerns mentioned in Major Fiber Therapy reviews based on feedback online and by phone.

1. Clumping 

Many users have reported issues with clumping as compared with the brand name Citrucel. This is the most prevalent issue with Major Fiber Therapy. Numerous Major Fiber Therapy reviews mention this issue.

2. Price

Some users note the price of Major Fiber Therapy is slightly more expensive than Citrucel. A Major Fiber Therapy review on Amazon states: 

" Citrucel is $14.99 for 30 oz., This Major brand is $17.00 for 13 oz. jar too expensive. the only reason I purchased it is Citrucel is out of stock or possibly out of business."

3. State of California Warning

Some users were concerned about the warning sticker on the side of the jar which states: "Warning: Consuming this product can expose you to chemicals including lead, which is known to the State of California to cause cancer." For more information, visit www.P65Warnings.ca.gov. A full list of ingredients that require this warning in California, can be found on the California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment website.

Major Fiber Therapy contains the following ingredients:

Active Ingredient: Methylcellulose (a non-allergenic fiber) 2g

Inactive Ingredients: Citric acid, FD&C yellow 6 aluminum lake, maltodextrin, flavor (natural and artificial), potassium citrate, silica, sucrose.

The ingredient, silica, is the reason for the California warning.  Silica is a naturally occurring compound that is found in various forms, and it is generally considered safe when used in appropriate amounts. In the context of medications and some food products, silica is often used as an excipient, which means it is added to formulations as a processing aid or for specific purposes like improving flow or preventing caking. 

In the case of Major Fiber Therapy, silica is used to reduce clumping when mixed with water. Ingesting small amounts of silica in medications or foods is generally considered safe for most people. If you have specific concerns about silica in medications or any other product, it's advisable to consult with a healthcare professional. They can provide guidance based on your individual health profile and address any potential concerns or allergies you may have.

Other medications and foods that contain silica (depends on the formulation):

Medications: 

• Advil (Ibuprofen)
• Tylenol (Acetaminophen)
• Aleve (Naproxen)
• Tums (Calcium Carbonate)
• Centrum (Multivitamin)

Foods:

• Kraft - Some shredded cheese products may contain silica to prevent caking.
• Jell-O (Kraft Heinz) - Certain gelatin desserts or mixes may contain silica.
• Clif Bar - Some energy bars may use silica as an anti-caking agent.

You may view the full drug facts label including active and inactive ingredients for Major Fiber Therapy at the end of this blog post. 

Solutions for Major Fiber Therapy

1. Clumping

When compared with the brand name Citrucel, the largest number of complaints about Major Fiber Therapy are clumping. Clumping is an issue where the powder doesn't dissolve completely or coagulates.

We created a blog post for this issue:  Major Fiber Therapy (Citrucel) Dissolving Tips and Tricks.

Solution for Clumping

Use lukewarm to warm water. Users have confirmed this works well. It is important not to use hot water as this may cause the efficacy to be decreased.

2. High Prices

Some Major Fiber Therapy reviews complain about pricing which ranges from $15.99 to $29.99 per 16 oz jar. Some resellers on Amazon are taking advantage of the Citrucel shortage situation combined with Amazon marketplace fees for sellers, leading to price inflation. The product is non-returnable on Amazon.

Solution for High Prices

Shop around. We offer Major Fiber Therapy for $15.99 per 16 oz jar. Bulk discounts drop the price to as low as $9.99 per jar.

3. Taste

Some Major Fiber Therapy reviews complain about taste. While taste hasn't been a major factor, some users have reported the taste is neutral. Like all powder solutions, taste often depends on the user.

We created a blog post for this issue: Citrucel: 10 Ways to Make It Taste Better.

Solution to Improve Taste

Users have reported adding honey or agave syrup works the best. 

Why are Major Fiber Therapy Reviews Mixed?

No pun intended :-) Like any high-quality generic, especially those in powder form, Major Fiber Therapy has its pluses and minuses.  With over 150 reviews, Major Fiber Therapy has a 4.1 / 5 rating on xeteor.com and a lower 2.9 / 5 rating on Amazon. The higher rating on xeteor.com can be attributed to additional tips that are provided with every purchase and our generous return policy.

1. Amazon requires sellers to ship the product and receipt only. Sellers are typically not allowed (and usually don't) include additional information as they risk violating Amazon's marketplace policies.

2.  Amazon Prime customers do not receive any additional information on the best ways to use Major Fiber Therapy. 

3.  No product is perfect, and every product has its pluses and minuses. Many issues with Major Fiber Therapy can be resolved using the tips and tricks provided. 

4.  This product is non-returnable on Amazon.  xeteor.com offers a 100% satisfaction guarantee with free return shipping and an industry leading 100-day return policy.

We provide tips with every purchase of Major Fiber Therapy to ensure you get the best experience with this product. In addition, we offer a 100-day return policy and we're always available to answer questions over the phone at 1-833-787-4777 (M - F, 9 am - 5 pm PST).

Where Can I Read Major Fiber Therapy Reviews for Myself?

1.  Amazon.com (30 reviews)

2.  xeteor.com (1500+ reviews)

Major Fiber Therapy Methylcellulose Powder – 16 oz | Compare to Citrucel

$13.99

Major Fiber Therapy Methylcellulose Powder – 16 oz Orange Flavor | Compare to Citrucel® The Direct Replacement for Citrucel® with Sugar Major Fiber Therapy Powder...… read more

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Major Fiber Therapy Methylcellulose Powder – 16 oz | Compare to Citrucel (2 Pack)

$26.99

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Major Fiber Therapy Methylcellulose Powder – 16 oz | Compare to Citrucel (4 Pack)

$48.99

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Major Fiber Therapy Methylcellulose Powder – 16 oz | Compare to Citrucel (12 Pack)

$118.99

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About Xeteor

xeteor.com, founded in Las Vegas in 2018, is a trusted online guide and curated retailer for generic over-the-counter (OTC) medications. We operate like a family-owned business, prioritizing Supply Chain Stability and manufacturing transparency.

We are the creators of the Xeteor Rx Quality Ladder and the "Premium vs. Value" curation strategy. We use these frameworks to vet every product we sell.

Our portfolio includes:

• Premium Generics: GoodSense (Perrigo) and Foster & Thrive (McKesson).
• Specialist Brands: Reliable 1 Laboratories (High-Purity), Oncor Pharmaceuticals (US-Manufactured), and CareSens (Diabetes Care).
• Value Generics: Major Pharmaceuticals and Rugby Laboratories.

Recognized as a Top Rated seller on Trustpilot, Google, eBay, Amazon, and Walmart, we remain the authoritative source for honest generic drug advice. Our mission is to empower you with reliable products and educational content, all backed by a U.S.-based team that offers real human support and secure, senior-preferred payment options.

Shipping

Orders placed by 3:00 PM PST, Monday–Friday, ship the same day. We offer free nationwide shipping on orders over $30 and on all qualifying Savings Packs. Average delivery time is 3.3 business days. View our full shipping policy here.

Payment Methods

We accept Visa, Mastercard, Discover, American Express, PayPal, Venmo, Google Pay, and Apple Pay.

Risk-Free Returns

All purchases are backed by our 100-day satisfaction guarantee. Not happy with your order? Return it for free. View our complete return policy here.

Need Help?

We’re here for you. Reach out via:

• Phone:1-833-787-4777 (M–F, 9 AM–5 PM PST)
• Email:[email protected]
• Text:702-659-7022

Visit our full Contact Us page for more options.

Full Drug Facts Label for Major Fiber Therapy (Citrucel)

Active Ingredients

• Methylcellulose - 2g (a non-allergenic fiber)
• Purpose: Bulk-Forming Fiber Laxative

Uses

• Relieves constipation (irregularity)
• Helps to restore and maintain regularity
• For treating bowel disorders when recommended by a doctor
• Generally provide effect in 12-72 hours

Warnings

• CHOKING:
  • Taking this product without adequate fluid may cause it to swell and block your throat or esophagus and may cause choking
  • Do not take this product if you have difficulty in swallowing
  • If you experience chest pain, vomiting, or difficulty in swallowing or breathing after taking this product, seek immediate medical attention
• Ask a Doctor Before Use if You Have
  • Abdominal pain, nausea or vomiting
  • A sudden change in bowel habits that persists over a period of 2 weeks
  • Sensitivity to any of the ingredients
• Stop Use and Ask a Doctor If
  • You have rectal bleeding
  • You fail to have a bowl movement after use
  • These could be signs of a serious condition
• Keep Out of Reach of Children
  • In case of overdose, get medical help or contact a Poison Control Center right away at 1-800-222-1222
• When Using This Product
  • Do not exceed recommended maximum daily dose unless directed by a doctor
  • Do not use laxative products for a period longer than one week unless directed by a doctor

Directions

• MIX THIS PRODUCT (CHILD OR ADULT DOSE) WITH AT LEAST 8 OUNCES (A FULL GLASS) OF WATER OR OTHER FLUID
• TAKING THIS PRODUCT WITHOUT ENOUGH LIQUID MAY CAUSE CHOKING
• SEE CHOKING WARNING
• Use product at the first sign of constipation or irregularity
• Put one dose in a full glass of cold water
• Stir briskly and drink promptly
• Drinking another glass of water is helpful
• Adults & Children Above 12 years of age and over
  • One rounded tablespoon
  • (19 g) in 8 ounces of water fluid up to 3 times daily at the first sign of constipation or irregularity
• Children 6-12 Years of age
  • Half the adult dose in 8 ounces of water once daily
• Children under 6 years of age
  • Ask a doctor

Other Information

• Each adult dose contains approximately
• 3mg of sodium
• 105mg potassium
• Contributes 60 calories from sucrose and sorbitol
• Store at room temperature
• Protect contents from humidity
• Keep tightly closed

Inactive Ingredients

• Citric Acid, FD&C Yellow 6 Aluminum Lake, Maltodextrin, Flavor (natural and artificial), Potassium Citrate, Silica, Sucrose