Major Original Nasal Decongestant Spray 12 Hour Relief - 0.5 Fl Oz | Afrin

• Compare to the active ingredient in Afrin Original 
• Oxymetazoline HCl 0.05%
• Fast, powerful congestion relief
• For colds and allergies 
• Up to 12 hour relief 
• Maximum strength
• This product starts to work in seconds providing up to 12 hours of nasal congestion relief without drowsiness
• Up to 12-hour relief from nasal congestion
• Relief lasts All-Day or All-Night

Expiration Date: 4-2026

Ingredients

• Active: Oxymetazoline Hydrochloride 0.05% - Nasal Decongestant
• Inactive: Benzalkonium Chloride, Disodium EDTA, Disodium Phosphate, Glycerin, PEG-6, Propylene Glycol, PVP, Sodium Phosphate, Water (Purified)

Uses

• Temporarily relieves nasal congestion due to:
• Common cold
• Hay fever
• Upper respiratory allergies
• Temporarily relieves sinus congestion and pressure
• Shrinks swollen nasal membranes so you can breathe more freely

FULL DESCRIPTION

Drug Facts

Active Ingredients

• Oxymetazoline Hydrochloride - 0.05%
• Purpose: Nasal Decongestant

Uses

• Temporarily relieves nasal congestion due to:
• Common cold
• Hay fever
• Upper respiratory
• Temporarily relieves sinus congestion and pressure
• Shrinks swollen nasal membranes so you can breathe more freely

Warnings

• Ask a Doctor Before Use if You Have
• Heart disease 
• Thyroid disease
• High blood pressure
• Diabetes
• Trouble urinating due to an enlarged prostate gland
• When Using This Product
• Do not use more than directed
• Do not use for more than 3 days
• Use only as directed, frequent or prolonged use may cause nasal congestion to recur or worsen
• Temporary discomfort such as burning, stinging, sneezing or an increase in nasal discharge may occur
• Use of this container by more than one person may spread infection
• Stop Use and Ask a Doctor If
• Symptoms persist
• If Pregnant or Breast Feeding
• Ask a health professional before use
• Keep Out of Reach of Children
• If swallowed, get medical help or contact a Poison Control Center right away

Directions

• Adults and Children 6 to under 12 years of age (with adult supervision)
• 2 or 3 sprays in each nostril not more often than every 10 to 12 hours
• Children Under 6 years of age
• Ask a doctor
• To Use
• Push firmly down on cap and turn counter clockwise
• To Spray
• Squeeze bottle quickly and firmly
• Do not tilt head backward while spraying
• Wipe nozzle clean after use
• Secure cap after use

Other Information

• Store at room temperature
• Keep this carton for future reference on full labeling

Inactive Ingredients

• Benzalkonium Chloride, Benzyl Alcohol, Edetate Disodium, Polyethylene Glycol, Povidone, Propylene Glycol, Purified Water, Sodium Phosphate Dibasic, Sodium Phosphate Monobasic

What are the benefits of Major 12 Hour Nasal Decongestant Spray for Colds and Allergies Oxymetazoline HCl 0.05% - 0.5 Fl Oz?

Major 12 Hour Nasal Decongestant Spray for Colds and Allergies Oxymetazoline HCl 0.05% - 0.5 Fl Oz starts to work in seconds providing up to 12 hours of nasal congestion relief without drowsiness. It temporarily relieves nasal congestion due to: common cold, hay fever, upper respiratory allergies. It also temporarily relieves sinus congestion and pressure shrinking swollen nasal membranes so you can breathe more freely. The active ingredients is Oxymetazoline Hydrochloride - 0.05%, a nasal decongestant.

Major 12 Hour Nasal Decongestant Spray for Colds and Allergies Oxymetazoline HCl 0.05% - 0.5 Fl Oz is a nasal decongestant used to relieve nasal congestion caused by conditions such as allergies, hay fever, and the common cold.

Some potential benefits of using oxymetazoline spray may include:

1. Relief from nasal congestion: The primary benefit of Major 12 Hour Nasal Decongestant Spray for Colds and Allergies Oxymetazoline HCl 0.05% - 0.5 Fl Oz is its ability to relieve nasal congestion by constricting the blood vessels in the nasal passages, which reduces swelling and allows air to flow more easily.

2. Quick onset of action: Major 12 Hour Nasal Decongestant Spray for Colds and Allergies Oxymetazoline HCl 0.05% - 0.5 Fl Oz works quickly to provide relief from nasal congestion, often within minutes of use.

3. Extended relief: Major 12 Hour Nasal Decongestant Spray for Colds and Allergies Oxymetazoline HCl 0.05% - 0.5 Fl Oz can provide relief from nasal congestion for up to 12 hours, which can be particularly helpful for people who suffer from chronic congestion.

4. Improved breathing: By reducing nasal congestion, Major 12 Hour Nasal Decongestant Spray for Colds and Allergies Oxymetazoline HCl 0.05% - 0.5 Fl Oz can improve breathing, which can lead to better sleep and increased overall comfort.

It is important to note that while oxymetazoline spray can be an effective treatment for nasal congestion, it should not be used for more than three days in a row without consulting a doctor. Overuse of nasal decongestants like oxymetazoline can lead to a condition called rebound congestion, where the nasal passages become even more congested after the medication wears off.

Why shouldn't you use Afrin for more than 3 days?

Afrin is a brand name for a nasal spray containing the active ingredient oxymetazoline. It is classified as a topical decongestant and is used to temporarily relieve nasal congestion caused by allergies, sinus congestion, or the common cold.

Using Afrin or other similar nasal sprays for more than three consecutive days can lead to a condition called "rebound congestion" or "rhinitis medicamentosa." This condition occurs when the blood vessels in the nasal passages become dependent on the medication to maintain their normal size and function. As a result, when you stop using the nasal spray, the blood vessels can dilate excessively, causing even worse nasal congestion than before.

Rebound congestion can create a cycle where the more you use the nasal spray, the worse the congestion becomes when you stop using it, leading to a continued dependence on the medication. This can make it difficult to breathe through the nose and may require prolonged treatment to resolve.

To avoid rebound congestion and potential dependency, it is generally recommended to use nasal decongestant sprays like Afrin for a maximum of three consecutive days. If nasal congestion persists beyond this timeframe, it is advisable to consult with a healthcare professional for further evaluation and to explore alternative treatment options.

There are other non-medicated approaches that can help alleviate nasal congestion, such as saline nasal sprays or rinses, humidifiers, staying hydrated, and using over-the-counter oral decongestants (but these should also be used for a limited duration and as directed). It's important to follow the instructions provided by healthcare professionals and product labels for safe and effective use of any medication or treatment.

Why can't you use Afrin long term?

Afrin (oxymetazoline) is a topical nasal decongestant spray that works by constricting the blood vessels in the nasal passages, reducing swelling and congestion. While Afrin can provide quick and effective relief from nasal congestion, it is not intended for long-term use. There are several reasons why Afrin should not be used long term:

1. Rebound Congestion: Prolonged use of Afrin can lead to a condition called rebound congestion or rhinitis medicamentosa. This occurs when the blood vessels in the nasal passages become dependent on the medication to maintain their normal size and function. When you stop using Afrin after long-term use, the blood vessels may dilate excessively, resulting in even worse nasal congestion than before.

2. Tolerance: Over time, your body can develop tolerance to the effects of Afrin. This means that the medication becomes less effective at relieving congestion, and you may need to use higher doses or more frequent applications to achieve the same relief.

3. Side Effects: Afrin can cause side effects when used long term, including nasal dryness, irritation, and damage to the nasal mucosa. These side effects can worsen with prolonged use and may lead to other complications, such as nasal bleeding or sinus infections.

4. Systemic Absorption: Although the systemic absorption of oxymetazoline is relatively low, long-term use of Afrin can still result in some systemic absorption of the medication, which may increase the risk of systemic side effects.

It's important to follow the instructions provided by healthcare professionals and product labels when using Afrin or any other nasal decongestant. If nasal congestion persists beyond a few days or if you require ongoing relief, it is advisable to consult with a healthcare professional. They can evaluate your condition and recommend alternative treatment options that are safe and suitable for long-term use.

Which is better Flonase or Afrin?

Flonase (fluticasone) and Afrin (oxymetazoline) are both medications used for nasal congestion, but they have different mechanisms of action and are intended for different purposes. The choice between Flonase and Afrin depends on the underlying cause of congestion and individual needs.

Flonase is a corticosteroid nasal spray that works by reducing inflammation in the nasal passages. It is commonly used for the treatment of allergic rhinitis, including seasonal allergies and year-round allergies. Flonase is typically used on a daily basis for ongoing allergy management and is effective at relieving nasal congestion, sneezing, itching, and runny nose associated with allergies.

Afrin, on the other hand, is a topical decongestant nasal spray. It works by constricting the blood vessels in the nasal passages, reducing swelling and congestion. Afrin provides rapid relief of nasal congestion but is intended for short-term use, typically up to three consecutive days. Prolonged use of Afrin can lead to rebound congestion and dependency, as discussed in the previous response.

In summary, if you are experiencing nasal congestion due to allergies, Flonase may be a better choice as it targets the underlying inflammation and can provide long-term relief. However, if you have temporary congestion due to a cold or sinus congestion, Afrin may offer more immediate relief. It's important to follow the recommended usage instructions and consult with a healthcare professional if you have any specific concerns or questions about which medication is best for your situation.

What are the side effects of Afrin nose spray?

Afrin (oxymetazoline) nasal spray can cause side effects, although not everyone experiences them. Common side effects of Afrin may include:

1. Nasal Dryness and Irritation: Afrin can cause dryness, burning, or stinging sensations in the nose. Prolonged use of Afrin can exacerbate nasal dryness and discomfort.

2. Rebound Congestion: Long-term or excessive use of Afrin can lead to rebound congestion or rhinitis medicamentosa. This condition causes worsening nasal congestion when the medication is discontinued.

3. Sneezing or Increased Nasal Discharge: Some individuals may experience increased sneezing or nasal discharge while using Afrin.

4. Nausea or Headache: These side effects are less common but can occur in some individuals who use Afrin.

5. Elevated Blood Pressure: Afrin can cause a temporary increase in blood pressure in some people. If you have high blood pressure or a heart condition, it is advisable to consult with a healthcare professional before using Afrin.

6. Sleep Disturbances: Although less common, Afrin can cause sleep disturbances such as difficulty falling asleep or staying asleep, especially if used shortly before bedtime.

It's important to follow the recommended usage instructions and not exceed the recommended duration of use to minimize the risk of side effects. If you experience severe or persistent side effects, or if you have any concerns about using Afrin, it is recommended to consult with a healthcare professional for further guidance.

Are Afrin and Flonase the same?

No, Afrin (oxymetazoline) and Flonase (fluticasone propionate) are not the same medication. They belong to different classes of drugs and have different mechanisms of action, uses, and potential side effects.

Afrin is a nasal decongestant that works by constricting blood vessels in the nasal passages, reducing swelling and congestion. It provides temporary relief from nasal congestion caused by allergies, colds, or sinusitis. Afrin is typically used for short-term relief, usually for a maximum of three days, as prolonged or excessive use can lead to a condition called rebound congestion.

On the other hand, Flonase is a nasal corticosteroid. It works by reducing inflammation in the nasal passages, thereby alleviating symptoms associated with allergies, such as nasal congestion, sneezing, itching, and runny nose. Flonase is used for the long-term management and prevention of allergic rhinitis (hay fever) symptoms.

While both Afrin and Flonase can provide relief from nasal congestion, they have different mechanisms of action and uses. Afrin is a decongestant that provides immediate but short-term relief, while Flonase is a corticosteroid that provides long-term control of nasal allergy symptoms.

It's important to note that the use of any medication should be based on the guidance of a healthcare professional. They can evaluate your specific symptoms, medical history, and provide personalized recommendations for the most appropriate treatment option for your condition.

What is the generic name of Afrin?

The generic name of Afrin is oxymetazoline. Afrin is a brand name for the medication, and it contains the active ingredient oxymetazoline hydrochloride. The generic form of Afrin, which contains the same active ingredient, is available under various brand names or as store-brand versions. When purchasing generic versions, it's important to check the label for the active ingredient "oxymetazoline" to ensure you are getting the equivalent medication.

What is a safe alternative to Afrin?

If you are looking for a safe alternative to Afrin (oxymetazoline), there are several options available. Here are a few alternatives that can help relieve nasal congestion:

1. Saline Nasal Sprays or Rinses: Saline nasal sprays or rinses contain a solution of salt and water. They help to moisturize and rinse the nasal passages, reducing congestion and promoting nasal comfort. Saline sprays are non-medicated and can be used frequently throughout the day as needed. They are generally safe and well-tolerated, even for long-term use.

2. Nasal Corticosteroid Sprays: Nasal corticosteroid sprays, such as Flonase (fluticasone propionate), Nasacort (triamcinolone acetonide), or Rhinocort (budesonide), can be effective for relieving nasal congestion caused by allergies. These sprays work by reducing inflammation in the nasal passages and are generally safe for long-term use when used as directed.

3. Oral Decongestants: Over-the-counter oral decongestants, such as pseudoephedrine or phenylephrine, can provide relief from nasal congestion. However, it's important to use them with caution, as they can have systemic effects and may not be suitable for everyone, especially those with certain medical conditions or taking certain medications. It's advisable to consult with a healthcare professional or pharmacist before using oral decongestants.

4. Nasal Antihistamines: For nasal congestion caused by allergies, nasal antihistamines like azelastine (Astelin) or olopatadine (Patanase) can provide relief. These medications work by blocking histamine, a chemical released during an allergic reaction. They can help reduce congestion and other allergy symptoms.

It's important to note that the choice of alternative will depend on the underlying cause of your congestion, any other medical conditions you may have, and other medications you may be taking. It's always best to consult with a healthcare professional or pharmacist to determine the most appropriate and safe alternative for your specific situation.

What nasal spray is similar to Afrin?