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Laxatives & Constipation


Effective Laxatives and Constipation Relief Without the High Price

Shop a wide range of over-the-counter laxatives, stool softeners, and fiber supplements designed to relieve occasional or chronic constipation—without the markup you’ll find at big chain pharmacies.

Whether you need gentle overnight relief, bulk-forming fiber for daily support, or a fast-acting stimulant formula, we offer trusted generics that compare to brands like Dulcolax®, MiraLAX®, Colace®, and Citrucel®.

Our constipation relief products are ideal for seniors, post-surgery recovery, travel-related changes, and those on medications that may slow digestion. All items ship fast and qualify for bulk savings on multi-packs.

Common categories include: stimulant laxatives, stool softeners, osmotic laxatives, and fiber therapy powders.

Need help choosing the right option? Our support team is available to answer your questions.


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  • Major Bisacodyl Laxative - 1000 Tablets (Dulcolax) New Bottle Major Bisacodyl 5 mg Stimulant Laxative - 1000 Tablets | Dulcolax

    Major Bisacodyl 5 mg Stimulant Laxative - 1000 Tablets | Dulcolax

    Major
    $11.99
    Major Bisacodyl Stimulant Laxative 5 mg – 100 Tablets | Compare to 5 mg Dulcolax Buy stimulant laxatives online and save. These Major Bisacodyl 5 mg tablets are a fast-acting solution for occasional constipation relief. Each tablet contains the...
  • Major Extra Strength Docusate Sodium 250 mg - 100 softgels New Look Major Docusate Sodium 250 mg Bulk Pricing

    Major Docusate Sodium 250 mg - 100 Softgels | Extra Strength Colace

    Major
    $7.99
    Major Extra Strength Docusate Sodium 250 mg – 100 Softgels | Compare to Colace® Save money on gentle constipation relief. This extra strength formula from Major Pharmaceuticals delivers the same active ingredient as Colace® Extra...
  • Major Extra Strength Docusate Sodium 250 mg - 1000 Softgels (Colace) Major Docusate Sodium 250 mg Bulk Pricing

    Major Docusate Sodium 250 mg - 1000 Softgels | Extra Strength Colace

    Major
    $45.99
    Major Extra Strength Docusate Sodium 250 mg – 1000 Softgels | Compare to Colace® Gentle, Bulk Relief for Occasional Constipation Backed up and strained? This bulk bottle contains 1000 softgels of Major Docusate Sodium 250 mg—the same...
  • Rugby Senna Leaf Extract Syrup 176mg/5mL Dietary Supplement - 8 Fl Oz Rugby Senna Leaf Extract Syrup 176mg/5mL Dietary Supplement - 8 Fl Oz is chocolate flavored

    Rugby Senna Syrup 8 fl oz – 176 mg/5 mL for Constipation Relief

    Rugby
    $12.95
    Rugby Senna Syrup – 8 fl oz | Senna Leaf Extract 176 mg/5 mL | Chocolate Flavor Rugby Senna Syrup provides effective overnight relief from occasional constipation. Each teaspoon contains 176 mg of senna leaf extract (as sennosides), a stimulant...
  • Rugby Docusate Sodium Liquid 50 mg/5 ml Stool Softener Cherry - 16 Fl Oz Rugby Docusate Sodium Liquid 50 mg/5 ml Stool Softener Cherry - 16 Fl Oz Drug Facts

    Rugby Docusate Sodium Liquid 50 mg / 5 mL Stool Softener - 16 fl oz | Colace Liquid

    Rugby
    $16.99
    Liquid Stool Softener with Docusate Sodium 50 mg & Sennosides 8.6 mg – Gentle Overnight Relief | Compare to Senexon-S If you're looking for a liquid alternative to Colace, this dual-action stool softener is designed to work gently overnight...
  • Major Docusate Sodium 100 mg - 100 Softgels (Colace Regular Strength) Bottle Major Docusate Sodium 100 mg - 100 Softgels (Colace Regular Strength) Bottle Drug Facts

    Major Docusate Sodium 100 mg - 100 Softgels | Colace

    Major
    $6.99
    Major Docusate Sodium 100 mg – 100 Softgels | Colace Regular Strength Stool Softener Note: This 100 mg strength is not commonly stocked on xeteor.com because over 98% of customers prefer the stronger 250 mg softgels for more effective relief. We...
  • Rugby PEG Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz (MiraLAX) Rugby Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz (MiraLAX) Drug Facts

    Rugby PEG Polyethylene Glycol 3350 Powder Osmotic Laxative - 17.9 oz | MiraLAX

    Rugby
    $19.99
    Gentle Constipation Relief with Polyethylene Glycol 3350 Powder Rugby PEG 3350 Powder is a trusted, unflavored osmotic laxative that provides gentle, effective relief from occasional constipation. It contains the same active ingredient as...
  • Major DOK Docusate Sodium Stool Softener 100 mg - 100 Crushable Tablets  Bottle

    Major DOK Docusate Sodium Stool Softener 100 mg - 100 Crushable Tablets

    Major
    $8.49
    Major DOK Docusate Sodium Stool Softener 100 mg - 100 Crushable Tablets Achieve Comfortable Bowel Movements Again - Major DOK Suffering from painful, straining constipation? Major DOK gently softens stool overnight using docusate sodium, the #1 doctor...
  • Rugby Senna Liquid - 8 Fl Oz Natural Vegetable Laxative - 3 Pack Rugby Senna Liquid - 8 Fl Oz Natural Vegetable Laxative - 3 Pack - Drug Facts

    Rugby Senna Liquid 8 fl oz (3 Pack) – 8.8 mg Sennosides Chocolate Laxative

    Rugby
    $34.98
    Rugby Senna Liquid 8 fl oz (3 Pack) – 8.8 mg Sennosides Chocolate Laxative This 3-pack of Rugby Senna Liquid provides effective overnight relief from occasional constipation. Each teaspoon (5 mL) contains 8.8 mg of sennosides, a natural vegetable...
  • Rugby Senna Leaf Extract Syrup 176mg/5mL Dietary Supplement - 8 Fl Oz is chocolate flavored Bottle Rugby Senna Leaf Extract Syrup 176mg/5mL Dietary Supplement - 8 Fl Oz is chocolate flavored

    Rugby Senna Liquid 8 fl oz – 8.8 mg Sennosides Chocolate Laxative

    Rugby
    $14.99
    Rugby Senna Liquid 8 fl oz – 8.8 mg Sennosides Chocolate Laxative Rugby Senna Liquid provides gentle, overnight relief from occasional constipation. Each 5 mL teaspoon contains 8.8 mg of sennosides—a natural vegetable laxative ingredient...
  • Laxative Dulcolax® Tablet 100 per Box 5 mg Strength Bisacodyl Box This product is fulfilled by McKesson

    Dulcolax® Tablet 100 per Box 5 mg Strength Bisacodyl Laxative USP

    Dulcolax
    $30.30
    Dulcolax® Laxative Tablets – 100 Count | 5 mg Bisacodyl Looking to save? We also carry Major Bisacodyl — a generic version of Dulcolax® — for just $11.99 for 1000 tablets. That’s 90% less than the brand-name version. But...
  • Major Docusate Sodium 100 mg - 1000 Softgels (Colace Regular Strength) Major Docusate Sodium 100 mg - 1000 Softgels (Colace Regular Strength) Drug Facts

    Major Docusate Sodium 100 mg - 1000 Softgels | Colace

    Major
    $19.99
    Major Docusate Sodium 100 mg - 1000 Softgels | Colace Regular Strength Stool Softener Compare to the active ingredient in Colace Regular Strength Stool Softener Stool softener laxative Expiration Date: 9-2025 Ingredients Active: Docusate Sodium...