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Over-The-Counter


Affordable Over-the-Counter Medicines Without the Brand-Name Price

Looking for low-cost relief without sacrificing quality? Our over-the-counter selection includes trusted generics that compare to top brands like Mucinex®, Colace®, Robitussin®, Citrucel®, and Phazyme®—all at everyday low prices.

From stool softeners like Docusate Sodium to guaifenesin cough syrups without dextromethorphan, we stock remedies for constipation, cough and cold, indigestion, hemorrhoids, and more. Many of our products are made by trusted manufacturers such as Foster & Thrive®, Rugby®, Major®, and Perrigo®.

  • Constipation Relief: Docusate Sodium, Bisacodyl, PEG 3350
  • Cough & Cold: Robafen DM, Liquid Guaifenesin, Mucus Relief
  • Pain Relief: Capsaicin Cream, Lidocaine Patches, Menthol Rubs
  • Allergies: Diphenhydramine, Cetirizine, Chlorpheniramine
  • Digestive Support: Simethicone, Methylcellulose, Antacids

Need help finding something? Check out our blog or contact us for personalized assistance. We offer fast shipping and discounts on bulk packs for caregivers, clinics, and families stocking up.

What ailment can we help you with today?


⭐ Top Over-the-Counter Deals

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  • Major Fiber Powder Therapy Methylcellulose Orange Flavor - 16oz (Citrucel) Major Fiber Therapy Powder Helps Relieve Stool Irregularity

    Major Fiber Therapy Methylcellulose Powder – 16 oz | Compare to Citrucel

    Major Pharmaceuticals
    $14.99
    Major Fiber Therapy Methylcellulose Powder – 16 oz Orange Flavor | Compare to Citrucel® The Direct Replacement for Citrucel® with Sugar Major Fiber Therapy Powder is the direct generic replacement for the original Citrucel® Orange...
  • Rugby Maximum Strength Pain Relieving Cream - 3 oz (Thera-Gesic) Where Can I Buy Rugby Pain Relieving Cream

    Rugby Pain Relieving Cream – 3 oz | Compare to Thera-Gesic

    Rugby Laboratories
    $6.99
    Rugby Pain Relieving Cream – 3 oz | Compare to Thera-Gesic® Maximum Strength Relief for Aches & Pains Experience fast-acting relief with Rugby Pain Relieving Cream. This trusted generic alternative to Thera-Gesic® features a maximum...
  • Rugby Chest Congestion Relief DM - 60 Tablets (Mucinex DM) Rugby Chest Congestion Relief DM Temporarily relieves coughs that occur with a common cold.

    Rugby Chest Congestion Relief DM - 60 Tablets | Mucinex DM

    Rugby Laboratories
    $8.99
    Rugby Chest Congestion Relief DM – 60 Tablets | Compare to Mucinex DM® Powerful Cough Suppression and Expectorant for Clearer Breathing Rugby Chest Congestion Relief DM provides effective, daytime relief from persistent coughs and heavy chest...
  • Rugby Sodium Chloride Hypertonicity Opthalmic Ointment, 5% - 3.5 g | Muro 128 Ointment Rugby Sodium Chloride 5% Ointment Amazon

    Rugby Sodium Chloride Hypertonicity Ophthalmic Ointment 5% | Muro 128

    Rugby Laboratories
    $14.99
    Rugby Sodium Chloride Ophthalmic Ointment 5% – 3.5g Tube | Compare to Muro 128® Ointment Intensive Overnight Hypertonic Relief for Corneal Edema and Visual Clarity Restore comfort and clarity to your vision with Rugby Sodium Chloride Ophthalmic...
  •  Home Aid Pro Comfort Alcohol Pads - 100 Sheets   Home Aid Pro Comfort Alcohol Pads - 100 Sheets Side

    Home Aide Pro Comfort Alcohol Pads - 100 Sheets

    Home Aide
    $3.99
    Pro Comfort Alcohol Prep Pads – Box of 100 | Individually Wrapped Clean Skin. No Fuss. No Burn. Just Comfortably Pro. When it comes to prepping skin, Pro Comfort Alcohol Pads don’t mess around. These 2-ply, individually wrapped wipes are...
  • Rugby Ultra Strength Simethicone Antigas 180mg - 60 Softgels (Phazyme Ultra Strength) New bottle Rugby Simethicone 180 mg - Relief from gas pain, pressure and bloating

    Rugby Simethicone 180 mg - 60 Softgels | Ultra Strength Phazyme

    Rugby Laboratories
    $6.99
    Rugby Ultra Strength Simethicone 180 mg – 60 Softgels | Compare to Phazyme® Rugby Ultra Strength Simethicone 180 mg softgels provide fast-acting gas relief by helping break up gas bubbles that cause abdominal pressure, bloating, and discomfort...
  • Generic Muro 128 Drops | Rugby Sodium Chloride Hypertonicity Ophthalmic Solution 5% Compare Rugby Sodium Chloride Solution vs Muro 128 Solution

    Rugby Sodium Chloride Hypertonicity Ophthalmic Solution 5% | Muro 128

    Rugby Laboratories
    $12.99
    Rugby Sodium Chloride Ophthalmic Solution 5% – 0.5 fl oz | Compare to Muro 128® Drops Targeted Hypertonic Relief for Corneal Edema and Blurred Vision Restore clarity to your vision with Rugby Sodium Chloride Ophthalmic Solution 5%. This...
  • Perrigo Cetirizine 10mg - 300 Tablets (Zyrtec) Padagis Cetirizine 10mg - 300 Tablets (Zyrtec)  Benefits

    Perrigo Cetirizine Hydrochloride 10 mg - 300 Tablets | Zyrtec

    Perrigo
    $12.99
    Cetirizine Hydrochloride 10 mg Tablets – 300 Count | Generic Zyrtec® by Perrigo 24-Hour Allergy Relief for Less Perrigo Cetirizine Hydrochloride 10 mg delivers the same FDA-approved active ingredient as brand-name Zyrtec®—without the...
  • Major Thera-Gel Therapeutic Coal Tar Shampoo - 8.5 fl oz | Neutrogena T-Gel Major Thera-Gel Therapeutic Coal Tar Shampoo - 8.5 fl oz (Neutrogena T-Gel)

    Major Thera-Gel Therapeutic Coal Tar Shampoo - 8.5 fl oz | Neutrogena T-Gel

    Major Pharmaceuticals
    $9.99
    Major Thera-Gel Therapeutic Shampoo – 8.5 fl oz | Coal Tar Dandruff Shampoo Major Thera-Gel Shampoo offers relief for itchy, flaky scalps caused by dandruff, seborrheic dermatitis, or scalp psoriasis. With Coal Tar 0.5% (equivalent to 2% coal tar...
  • Rugby Sodium Chloride Ophthalmic Solution 5% | Muro 128 (3 Pack) Rugby Sodium Chloride Ophthalmic Solution 5% | 3 Pack

    Rugby Sodium Chloride Ophthalmic Solution 5% | Muro 128 (3 Pack)

    Rugby Laboratories
    $24.99
    Rugby Sodium Chloride Ophthalmic Solution 5% – 3 Pack | Compare to Muro 128® Drops Triple-Pack Value: Targeted Hypertonic Relief for Corneal Edema and Blurred Vision Restore clarity to your vision with this value 3-pack of Rugby Sodium Chloride...
  • Rugby Meclizine 25 mg - 100 Chewable Tablets (Bonine) Rugby Meclizine 25 mg - 100 Chewable Tablets (Bonine) Benefits

    Rugby Meclizine 25 mg - 100 Chewable Tablets | Bonine

    Rugby Laboratories
    $7.99
    Rugby Meclizine 25 mg Chewable Tablets – 100 Count | Compare to Bonine® Fast-Acting Relief for Motion Sickness, Nausea, and Vertigo Rugby Meclizine 25 mg Chewable Tablets provide reliable, non-prescription relief from nausea, vomiting, and...
  • Home Aide Pure Comfort Alcohol Prep Pads - 100 Packets Home Aide Pure Comfort Alcohol Prep Pads - 100 Packets Top of the Box

    Home Aide Pure Comfort Alcohol Prep Pads - 100 Pads

    Home Aide
    $3.99
    Saturated in 70% isopropyl alcohol. 100 2-ply sheets per box. Individually wrapped in foil packets. For individual, professional and hospital use. Antiseptic for preparation of skin prior to injection. Home Aide Pure Comfort Alcohol...
  • Major Bisacodyl Laxative - 1000 Tablets (Dulcolax) New Bottle Major Bisacodyl 5 mg Stimulant Laxative - 1000 Tablets | Dulcolax

    Major Bisacodyl 5 mg Stimulant Laxative - 1000 Tablets | Dulcolax

    Major Pharmaceuticals
    $11.99
    Major Bisacodyl Stimulant Laxative 5 mg – 1000 Tablets | Compare to Dulcolax® Predictable Overnight Relief for Occasional Constipation Get your digestive system back on track with Major Bisacodyl 5 mg. As a stimulant laxative, this medication...
  • Rugby High Potency Arthritis Pain Relieving Cream - 2 oz (Zostrix HP) Capsaicin Cream 0.075 Where to Buy

    Rugby Arthritis Pain Relieving Cream - 2 oz | Zostrix HP

    Rugby Laboratories
    $7.99
    Rugby Arthritis Pain Relieving Cream – 0.075% Capsaicin (2 oz) | Compare to Zostrix HP® Looking for a stronger alternative to Zostrix®? Rugby Arthritis Pain Relieving Cream 0.075% delivers the same high-strength active ingredient as Zostrix...
  • Rugby Anti-Itch Lotion 7.5 oz – Compare to Original Sarna Lotion Rugby Anti-Itch Lotion next to Original and New Sarna – Same Ingredients, Better Price

    Rugby Anti-Itch Lotion - 7.5 fl oz | Sarna

    Rugby Laboratories
    $10.99
    Rugby Anti-Itch Lotion – 7.5 fl oz | Compare to Sarna® Original Steroid-Free, Cooling Relief for Itchy and Irritated Skin Rugby Anti-Itch Lotion is a trusted Sarna generic alternative that delivers the same reliable relief you’ve trusted...
  • Xlear Saline Nasal Spray - 1.5 fl oz Xlear Uses

    Xlear Saline Nasal Spray - 1.5 fl oz

    Xlear
    $13.99
    Xlear Saline Nasal Spray with Xylitol – 1.5 fl oz | Natural Congestion Relief Fast, Drug-Free Relief for Clearer Breathing and Nasal Wellness Xlear Saline Nasal Spray is a patented, doctor-recommended solution designed to provide natural relief...
  • 5 pack of Major Nasal Decongestant Spray 1 fl oz bottles – generic Afrin pump spray for congestion relief Promotional image of Major Nasal Decongestant Spray 5 Pack – shows free shipping, made in USA, compares to Afrin, and highlights 5 fl oz total for sinus and nasal congestion relief

    Major Nasal Decongestant Spray - 1 fl oz | Compare to Afrin No Drip (5 Pack)

    Major Pharmaceuticals
    $27.99
    Major Nasal Decongestant Spray – 1 fl oz (5 Pack) | Compare to Afrin® No Drip Stock Up and Save on Fast, 12-Hour Congestion and Sinus Relief Don't let sinus pressure sideline your household. This 5-pack of Major Nasal Decongestant Spray 0.05%...
  • Major Prenatal Supplement - 100 Tablets New Bottle Major Prenatal Tablets - Benefits

    Major Prenatal Tablets - 100 Tablets

    Major Pharmaceuticals
    $6.49
    Major Prenatal Supplement – 100 Tablets | Compare to Stuart Prenatal Why Choose Major Prenatal Tablets? 100 tablets – over 3 months of daily support Formulated for pregnant and lactating women Includes folic acid, iron, calcium, and...
  • Major Extra Strength Docusate Sodium 250 mg - 100 softgels New Look 2026 Major Docusate Sodium 250 mg - New Bottle 2026

    Major Docusate Sodium 250 mg - 100 Softgels | Extra Strength Colace

    Major Pharmaceuticals
    $8.99
    Major Extra Strength Docusate Sodium 250 mg – 100 Softgels | Compare to Colace® Gentle, Extra Strength Relief for Occasional Constipation Major Extra Strength Docusate Sodium 250 mg is a stool softener that provides gentle and reliable relief...
  • Rugby Muscle Rub Cream 3oz Bengay Box Rugby Muscle Rub Cream Amazon

    Rugby Muscle Rub Cream - 3 oz | Bengay

    Rugby Laboratories
    $6.99
    Rugby Muscle Rub Cream – 3 oz | Compare to Bengay Rugby Muscle Rub Cream (3 oz) is a greaseless, fast-absorbing topical analgesic that provides powerful relief from muscle aches, arthritis pain, sprains, and backaches. Each tube contains 10%...
  • Major Cough & Cold - 16 Tablets (Coricidin HBP Cough & Cold) Major Cough & Cold - 16 Tablets Ingredients

    Major Cough & Cold HBP - 16 Tablets | Coricidin HBP

    Major Pharmaceuticals
    $5.99
    Major Cough & Cold HBP – 16 Tablets | Decongestant-Free Cold Relief Compare to Coricidin® HBP Safe and Effective Multi-Symptom Relief for Individuals with High Blood Pressure Managing a cold shouldn't mean compromising your cardiovascular...
  • Major Robafen Congestion Formula - 200 mg (Robitussin) Major Robafen Congestion Formula - 200 mg (Robitussin) Drug Facts

    Major Robafen Congestion Formula - 4 fl oz | Robitussin

    Major Pharmaceuticals
    $6.99
    Major Robafen Congestion Formula - 4 fl oz (Discontinued) Although Major Robafen Congestion Formula (Guaifenesin 200 mg) has been discontinued, you can still find effective relief from chest and nasal congestion with our top alternative. We recommend...
  • Front view of Foster & Thrive Adult Tussin Guaifenesin 200 mg Expectorant Syrup with no dextromethorphan Front view of a bottle of Foster & Thrive Adult Tussin Guaifenesin 200 mg Expectorant Syrup with no dextromethorphan

    Foster & Thrive Tussin Guaifenesin 200 mg Cough Syrup – 4 fl oz | Compare to Robitussin

    Foster & Thrive
    $10.99
    Foster & Thrive Tussin Guaifenesin 200 mg Cough Syrup – 4 fl oz | Compare to Robitussin Fast, affordable relief for stubborn chest congestion. Each 10 mL dose of Foster & Thrive Tussin delivers Guaifenesin 200 mg—the same expectorant...
  •  Major Banophen Diphenhydramine 50mg - 100 Capsules (Generic Benadryl)  Major Banophen Diphenhydramine 50mg - 100 Capsules (Generic Benadryl)  Drug Facts

    Major Banophen 50 mg - 100 Capsules | Benadryl

    Major Pharmaceuticals
    $6.99
    Major Banophen Diphenhydramine 50 mg – 100 Capsules | Compare to Benadryl® Compare to the active ingredient in Benadryl® Allergy Experience effective relief with Major Banophen 50 mg Capsules. This extra-strength formula delivers 50 mg of...
  • Rugby Dextromethorphan HBr USP 15 mg - 20 Softgels Rugby Dextromethorphan HBr USP 15 mg - 20 Softgels - Robitussin CoughGels

    Rugby Dextromethorphan HBr 15 mg - 20 Softgels | Robitussin CoughGels

    Rugby Laboratories
    $7.99
    Rugby Dextromethorphan HBr 15 mg Softgels – 20 Softgels | Compare to Robitussin® CoughGels Non-Drowsy, Maximum Strength Cough Suppression for Targeted Relief Quiet persistent, dry coughs with Rugby Dextromethorphan HBr 15 mg Softgels. Each...
  • Major B-Complex with B-12 Vitamins - 100 Tablets Major & Rugby B-Complex with B-12 Vitamins Discontinued - Best Alternative

    Rugby Vitamin B Complex with B-12 Vitamins - 100 Tablets

    Rugby Laboratories
    $8.99
    Rugby Vitamin B Complex with B-12 Vitamins – 100 Tablets Daily Support for Energy Metabolism & Nervous System Health Support your body's natural vitality with Rugby Vitamin B Complex with B-12 Vitamins. This high-potency daily supplement is...
  • Rugby Senna Leaf Extract Syrup 176mg/5mL Dietary Supplement - 8 Fl Oz Rugby Senna Leaf Extract Syrup 176mg/5mL Dietary Supplement - 8 Fl Oz is chocolate flavored

    Rugby Senna Syrup - 8 fl oz | Senna Leaf Extract 176 mg / 5 mL

    Rugby Laboratories
    $13.99
    Rugby Senna Syrup 176 mg per 5 mL – 8 fl oz | Chocolate Flavor Gentle Overnight Relief from Occasional Constipation Rugby Senna Syrup provides effective, gentle relief from occasional constipation using a natural stimulant laxative derived from...
  • Major Calamine Lotion 6 oz bottle – OTC treatment for poison ivy, oak, heat rash, and itchy skin Calamine Lotion Drug Facts – Active ingredients Calamine 8% and Zinc Oxide 8% for poison ivy, heat rash, and bug bite relief

    Major Calamine Lotion - 6 fl oz | Caladryl

    Major Pharmaceuticals
    $10.99
    Major Calamine Lotion – 8% Calamine & 8% Zinc Oxide – 6 fl oz Bottle Trusted Relief for Poison Ivy, Oak, Sumac, and Insect Bites Major Calamine Lotion is a pharmacist-recommended, over-the-counter skin protectant formulated to provide...
  • Rugby Urea 20 Cream - 3 oz Urea Cream 20 vs 40

    Rugby Urea 20 Intensive Hydrating Cream - 3 oz

    Rugby Laboratories
    $11.99
    Rugby Urea 20 Cream – 3 oz | Hydrating Urea 20% Moisturizer for Dry Skin Professional-Grade Hydration and Exfoliation for Rough, Callused Skin Rugby Urea 20 Cream is a specialized dermatologist-grade moisturizer designed to tackle the most stubborn...
  • Major Triple Antibiotic Ointment (Generic Neosporin) Major Triple Antibiotic Ointment (Generic Neosporin)  Back Side

    Major Triple Antibiotic Ointment 1 oz – Compare to Neosporin®

    Major Pharmaceuticals
    $6.79
    Major Triple Antibiotic Ointment – 1 oz | Generic Neosporin® for Cuts, Scrapes & Burns Generic Neosporin® at a better price—same ingredients, same protection. This over-the-counter triple antibiotic ointment contains the same...
  • Rugby Capsaicin Cream 0.025% generic Zostrix alternative for nerve and arthritis pain Rugby Capsaicin Cream Price Comparison – Save vs Amazon and Walmart on 2 oz Single Tube

    Rugby Capsaicin Cream 0.025% - 2 oz | Zostrix

    Rugby Laboratories
    $6.99
    Rugby Capsaicin Cream 0.025% – 2 oz | Compare to Zostrix® Compare to the active ingredient in Zostrix® Manage arthritis, nerve pain, and post-shingles discomfort affordably with Rugby Capsaicin Cream 0.025%. Containing the same active...
  • Major Robafen DM Cough Raspberry Cough Syrup - 24 Fl Oz - Savings Pack Major Robafen DM - 24 Fl Oz - 3 Pack

    Major Robafen DM Cough Syrup – 8 fl oz | Compare to Robitussin DM (3 Pack)

    Major Pharmaceuticals
    $20.99
    Major Robafen DM Cough Syrup – 3 Pack (24 fl oz) | Compare to Robitussin DM (3 Pack) Triple the size. Triple the value. This 3-pack of Major Robafen DM delivers a full 24 fl oz of cough and chest congestion relief—at a lower price than a...
  • Rugby Benzoyl Peroxide Wash 10% - 5 fl oz Rugby Benzoyl Peroxide Wash 10% - 5 fl oz - Clean Acne Free Skin

    Rugby Benzoyl Peroxide Wash 10% - 5 fl oz

    Rugby Laboratories
    $9.99
    Rugby Benzoyl Peroxide Wash 10% - 5 fl oz Helps to keep skin clear  Helps to dry oily skin Helps to clear acne pimples 5 fl oz  Expiration Date: 12-2026 Ingredients Active Ingredient: Benzoyl Peroxide USP 10% - Acne Medication Inactive...
  •  Major FeroSul 325 mg Ferrous Sulfate Iron Supplement - 100 Tablets | Feosol Major Ferosul 325 mg Iron Supplement - 100 Tablets - Label

    Major FeroSul Ferrous Sulfate 325 mg - 100 Tablets | Feosol

    Major Pharmaceuticals
    $7.99
    Major FeroSul Ferrous Sulfate 325 mg – 100 Tablets | Compare to Feosol® Major FeroSul Ferrous Sulfate is a trusted iron supplement designed to help prevent and treat iron deficiency anemia. Each specialty-coated tablet delivers 65 mg of...
  • Rugby Chest Congestion Relief PE - 60 Tablets (Mucinex Sinus) Major Mucus Sinus Relief - 60 Tablets (Mucinex Sinus) Comparison

    Rugby Chest Congestion Relief PE – 60 Tablets | Compare to Mucinex Sinus-Max

    Rugby Laboratories
    $10.99
    Rugby Chest Congestion Relief PE – 60 Tablets | Compare to Mucinex Sinus-Max® Dual-Action, Dye-Free Relief for Head and Chest Congestion Breathing through your nose shouldn't feel like a luxury. When "head-and-chest" congestion makes every...
  • Rugby Vitamin D3 Dietary Supplement 50 mcg (2000 IU) - 100 Tablets Rugby Vitamin D3 50 mcg (2000 IU) - Ingredients

    Rugby Vitamin D3 50 mcg (2000 IU) - 100 Tablets

    Rugby Laboratories
    $7.99
    Rugby Vitamin D3 50 mcg (2000 IU) – 100 Tablets | Immune & Bone Health Support Rugby Vitamin D3 delivers 50 mcg (2,000 IU) of cholecalciferol in each tablet to help maintain healthy bones, support calcium absorption, and promote immune system...

Over-the-counter (OTC) medications are non-prescription drugs that can be purchased without a prescription. These medications are intended to provide relief from common ailments and mild health conditions.