Zyrtec Generic Alternatives: Are They Just as Good?
Table of Contents
- Perrigo Cetirizine → Now Padagis (What Changed?)
- Why Consider Zyrtec Alternatives?
- Pros & Cons of Cetirizine (Zyrtec Generics)
- Zyrtec vs Perrigo/Padagis vs GoodSense (Cetirizine 10 mg)
- Price Comparison: Zyrtec Generic Alternatives (Price per Tablet)
- Explore Our Complete Cough & Cold Guides
- About Xeteor
- FAQs
Yes. Zyrtec generic alternatives are identical to and just as effective as name-brand Zyrtec. The FDA mandates that all generics use the exact same active ingredient — Cetirizine HCl 10mg — and meet the same strict standards for safety, strength, and effectiveness. The only difference is the price.
This expert guide proves it. We compare the ingredients, side effects, and help you choose the right option based on our Premium vs. Value philosophy: the "Premium" generic (GoodSense) or the "Value" generic (Major Pharmaceuticals).
Explore the full Cough, Cold & Flu Hub for all our expert guides.
Perrigo Cetirizine → Now Padagis (What Changed?)
Perrigo’s OTC cetirizine is transitioning to the Padagis label. The formula, dosage, and effectiveness remain the same—most shoppers will notice updated packaging, not a discontinuation. That means your preferred Zyrtec Generic Alternatives from Perrigo/Padagis still provide the same clinical relief and dosing you expect.
Why Consider Zyrtec Alternatives?
- Same active ingredient: Zyrtec and its generics all use cetirizine HCl 10 mg.
- FDA bioequivalence: Approved generics must match the brand for safety, strength, quality, and effectiveness.
- Lower cost per dose: Multi-packs and bulk bottles often reduce your cost without sacrificing relief.
- Flexible formats: Choose bottle sizes that fit seasonal or year-round use.
Deep-Dive Guides for Zyrtec Generic Alternatives
- Claritin vs Zyrtec (Loratadine vs Cetirizine) — pros, cons, and when to pick each.
- Equate vs Perrigo Cetirizine — retailer brand vs manufacturer label.
- Perrigo Cetirizine “Discontinued”? — what changed with the Padagis rebrand.
- GoodSense Children's Cetirizine Liquid — see product details, dosage information, and parental reviews.
Pros & Cons of Cetirizine (Zyrtec Generics)
✅ Pros
| ❌ Cons
|
Zyrtec vs Perrigo/Padagis vs GoodSense (Cetirizine 10 mg)
All three options contain cetirizine HCl 10 mg. For brand-vs-generic nuances within Zyrtec Generic Alternatives, see our Claritin vs Zyrtec comparison and Equate vs Perrigo Cetirizine guide.
| Option | Active Ingredient | What Stands Out | Typical Bottle Sizes |
|---|---|---|---|
| Zyrtec® (Brand) | Cetirizine HCl 10 mg | Familiar national brand | 24 ct, 30 ct, etc. |
| Perrigo/Padagis Cetirizine | Cetirizine HCl 10 mg | FDA-approved generic; strong value in bulk sizes | 300 ct (single), 300 ct (2-pack) |
| GoodSense Cetirizine | Cetirizine HCl 10 mg | Branded generic; everyday 90-count size and multi-pack | 90 ct (single), 90 ct × 2 (2-pack) |
Price Comparison: Zyrtec Generic Alternatives (Price per Tablet)
To make the best choice among Zyrtec Generic Alternatives, compare total price and price per tablet. Larger packs usually offer the best value.
| Product | Pack Size | Total Delivered Price | Price per Tablet | Notes |
|---|---|---|---|---|
| Perrigo/Padagis Cetirizine 10 mg (300 ct × 2) | 600 tablets | $26.99 with Free Shipping | $0.04 | Bulk multi-pack value |
| Perrigo/Padagis Cetirizine 10 mg (300 ct) | 300 tablets | $13.99 + $4.99 Ship = $18.98 | $0.06 | Lowest single-bottle cost per tab |
| GoodSense Cetirizine 10 mg (90 ct × 2) | 180 tablets | $19.99 with Free Shipping | $0.11 | Stock-up household size |
| GoodSense Cetirizine 10 mg (90 ct) | 90 tablets | $11.99 + $4.99 Ship = $16.98 | $0.19 | Everyday bottle |
| Zyrtec® 10 mg Tablets (Brand) | 24 tablets | $18.99 (Prime) | $0.79 | Amazon listing; brand name |
*Amazon price checked on October 9, 2025 and subject to change. As an Amazon Associate, we may earn from qualifying purchases.
Why shop Zyrtec Generic Alternatives at Xeteor? Transparent pricing, guaranteed fresh expiration dates, and real product support from our U.S.-based team—no mystery sellers, no stale stock.
Why Xeteor is a Better Choice Than Amazon Marketplaces
| Feature | Xeteor | Amazon |
|---|---|---|
| Verified Trustpilot Rankings | ✅ Consistently Top-Ranked | ❌ Varies by seller |
| Guaranteed Freshness | ✅ Expiration dates clearly listed | ❌ Unknown |
| Transparent & Fair Pricing | ✅ Consistent value every day | ❌ Prices fluctuate |
| Expert Product Support | ✅ Real guidance from our U.S. team | ❌ No product-specific help |
| Direct Phone Support | ✅ | ❌ No direct number |
| PayPal Checkout | ✅ Simple & secure | ❌ Not accepted |
| Returns | ✅ 100-day returns + free return shipping | ❌ Most OTC items non-returnable |
Explore Our Complete Cough & Cold Guides
Browse the full hub for seasonal care, comparisons, and shopping tips: Cough, Cold & Flu Resource Center.
- Robitussin Generic Alternatives
- Mucinex Generic Alternatives
- Coricidin HBP Generic Alternatives
- Afrin Generic Alternatives
- Benadryl Generic Alternatives
Further Reading on Zyrtec Generic Alternatives
Need broader cold & allergy help? Visit our Cough, Cold & Flu Hub for all guides.
Perrigo Cetirizine Hydrochloride 10 mg - 300 Tablets | Zyrtec
$13.99
Cetirizine Hydrochloride 10 mg Tablets – 300 Count | Generic Zyrtec® by Perrigo Save on allergy relief with this trusted Zyrtec® generic. Perrigo Cetirizine Hydrochloride...… read more
Padagis / Perrigo Antihistamine Allergy Relief - 300 Tablets (2 Pack)
$26.99
Cetirizine Hydrochloride 10 mg – 600 Tablets (2 Pack) | Generic Zyrtec® by Padagis / Perrigo Save more with our best value pack. This 2-pack...… read more
About Xeteor
xeteor.com, founded in Las Vegas in 2018, is a trusted online guide and curated retailer for generic over-the-counter (OTC) medications. We operate like a family-owned business, thoughtfully selecting and offering a portfolio of brands that includes premium generics like GoodSense and Foster & Thrive, as well as trusted options such as Major Pharmaceuticals, Rugby Laboratories, Oncor Pharmaceuticals, and CareSens. Recognized as a Top Rated seller on Trustpilot, Google, eBay, Amazon, and Walmart, we’re a trusted authority focused on building brand trust and earning consumer loyalty. Our mission is to empower you with reliable products and educational content, all backed by a U.S.-based team that offers real human support and secure, senior-preferred payment options.
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FAQs
Is generic Zyrtec the same as brand-name Zyrtec?
Yes. Generic Zyrtec (Cetirizine HCl 10mg) is identical to the brand name. The FDA requires it to have the exact same active ingredient, strength, and effectiveness.
Is Perrigo Cetirizine discontinued?
No. Perrigo is the world's largest manufacturer of store-brand generics, and their Cetirizine (the generic for Zyrtec) is still in full production. We stock it as our "Premium" pick, GoodSense and under Perrigo's Padagis brand.
Who makes store brand Zyrtec (like Equate)?
Most store-brand Cetirizine (including Walmart's Equate and our "Premium" pick, GoodSense) is manufactured by Perrigo. They are the trusted leader in generic OTC production.
Why do some Zyrtec generics cost more than others?
This is our "Premium vs. Value" philosophy. "Premium" generics (like GoodSense by Perrigo) have retail-friendly packaging. "Value" generics (like Major or Rugby) use a simpler box to offer the lowest possible price. The medicine inside is identical.
What if cetirizine makes me drowsy?
Drowsiness is uncommon but possible. If you’re sensitive to it, consider a less-sedating antihistamine such as loratadine (Claritin). Always follow label directions or consult a healthcare professional.
What if Zyrtec (cetirizine) makes me drowsy?
Drowsiness is a common side effect of Zyrtec. Claritin (Loratadine) is a different, non-drowsy active ingredient that might be a better choice. You can learn which is right for you in our expert guide, "Zyrtec vs. Claritin."
