Zyrtec Generic Alternatives: Best Cetirizine 10 mg Options
Table of Contents
- Quick Answer: What Is the Generic for Zyrtec?
- Perrigo/Padagis Cetirizine: Xeteor’s Best Value Option
- Major Cetirizine 10 mg: New Smaller-Count Option
- GoodSense Cetirizine: Clearance Inventory
- Why Consider Zyrtec Generic Alternatives?
- Is Generic Zyrtec the Same as Zyrtec?
- What Does Cetirizine 10 mg Do?
- Pros & Cons of Cetirizine (Zyrtec Generics)
- Zyrtec vs Perrigo/Padagis vs Major vs GoodSense
- Which Zyrtec Generic Alternative Should You Choose?
- How Does Zyrtec Compare With Claritin?
- Related Zyrtec and Cetirizine Guides
- About Xeteor
- Frequently Asked Questions
Zyrtec generic alternatives contain the same active ingredient used in brand-name Zyrtec®: cetirizine HCl 10 mg. For shoppers looking for a lower-cost option, generic cetirizine is available from several manufacturers in different bottle sizes and multi-packs. Xeteor currently carries options from Perrigo/Padagis, Major Pharmaceuticals, and GoodSense. For more allergy and seasonal-care comparisons, visit our Cough, Cold & Flu Hub.
You can also shop all cetirizine and generic Zyrtec products by brand and pack size, or use this guide to compare the options before choosing.
⚠️ October 2026 Update: Zyrtec Generic Alternatives
Xeteor currently has stable supply across our main adult and children’s cetirizine options from Perrigo/Padagis, Major Pharmaceuticals, and GoodSense.
Perrigo/Padagis Cetirizine 10 mg - 300 Tablets: ✅ Stable Supply
Major Cetirizine 10 mg - 45 Tablets: ✅ Stable Supply
GoodSense Cetirizine 10 mg - 90 Tablets: ✅ Stable Supply
GoodSense Children’s Cetirizine 1 mg/mL - 4 fl oz: ✅ Stable Supply
Quick Answer: What Is the Generic for Zyrtec?
| Product | Active Ingredient | Strength | Best Fit |
|---|---|---|---|
| Zyrtec® | Cetirizine HCl | 10 mg | Brand-name adult option |
| Perrigo/Padagis Cetirizine | Cetirizine HCl | 10 mg | Best value for larger quantities |
| Major Cetirizine | Cetirizine HCl | 10 mg | Smaller-count adult option |
| GoodSense Cetirizine | Cetirizine HCl | 10 mg | Clearance adult option while supplies last |
| GoodSense Children’s Cetirizine | Cetirizine HCl | 1 mg/mL | Children’s liquid option |
The main difference among these Zyrtec generic alternatives is not the active ingredient. They all use cetirizine HCl 10 mg in the adult tablet products shown above. The practical differences are manufacturer, package size, price, and availability.
Best Value Pick: Perrigo/Padagis Cetirizine
Perrigo/Padagis Cetirizine 10 mg remains Xeteor’s top value pick for shoppers who want a larger supply of generic Zyrtec. The 300-tablet bottle provides a long-term option, while the 2-pack offers an even larger 600-tablet supply.
Perrigo Cetirizine Hydrochloride 10 mg - 300 Tablets | Zyrtec (2 Pack)
$29.99
Cetirizine Hydrochloride 10 mg – 600 Tablets (2 Pack) | Generic Zyrtec® by Padagis / Perrigo Stock Up & Save: Bulk Allergy Relief + Free… read more
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Perrigo/Padagis Cetirizine: Xeteor’s Best Value Option
Perrigo/Padagis is the strongest fit for shoppers who use cetirizine regularly and want a larger quantity. Xeteor carries both a 300-tablet bottle and a 600-tablet 2-pack.
Both contain cetirizine HCl 10 mg, the same active ingredient and strength used in adult Zyrtec tablets.
For shoppers primarily concerned with long-term value, Perrigo/Padagis remains our first choice among the current Zyrtec generic alternatives we carry.
Major Cetirizine 10 mg: New Smaller-Count Option
Major Pharmaceuticals is a newer addition to Xeteor’s cetirizine assortment and gives shoppers a useful alternative to the very large Perrigo bottles.
- Major Cetirizine 10 mg – 45 Tablets: A smaller everyday bottle for shoppers who do not need several hundred tablets at once.
- Major Cetirizine 10 mg – 45 Tablets, 2-Pack: 90 total tablets for shoppers who want a larger supply while staying with the Major product.
Major uses the same cetirizine HCl 10 mg active ingredient found in Zyrtec and gives Xeteor a current smaller-count option alongside the bulk Perrigo/Padagis products.
Major Cetirizine 10 mg - 45 Tablets | Compare to Zyrtec (2 Pack)
$19.99
Major Cetirizine Hydrochloride 10 mg – 90 Tablets (2-Pack Bundle) | Compare to Zyrtec® Powerful 24-Hour Relief from Indoor and Outdoor Allergy Symptoms Experience prescription-strength,… read more
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GoodSense Cetirizine: Clearance Inventory
Xeteor is currently clearing remaining GoodSense cetirizine inventory and does not plan to make GoodSense the primary option in this category going forward.
If the product and pack size you want are still available, GoodSense remains another cetirizine HCl option. Once the remaining adult tablet inventory is gone, shoppers can compare Perrigo/Padagis and Major instead. GoodSense also remains available in a children’s liquid cetirizine formulation while current inventory lasts.
- GoodSense Cetirizine 10 mg – 90 Tablets
- GoodSense Cetirizine 10 mg – 90 Tablets, 2-Pack
- GoodSense Children’s Cetirizine 1 mg/mL – 4 fl oz
- GoodSense Children’s Cetirizine 1 mg/mL – 4 fl oz, 2-Pack
GoodSense All Day Allergy Cetirizine 10 mg - 90 Tablets | Compare to Zyrtec (2 Pack)
$9.99
GoodSense All Day Allergy Cetirizine 10 mg – 90 Tablets (2 Pack) | Compare to Zyrtec® Stock Up & Save: 6-Month Supply of Allergy Relief… read more
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GoodSense Children's All Day Allergy Cetirizine 1 mg / mL - 4 fl oz | Compare to Children's Zyrtec (2 Pack)
$16.99
GoodSense Children's All Day Allergy Cetirizine 1 mg / mL – 4 fl oz (2 Pack) | Compare to Children’s Zyrtec - Bubble Gum Flavor… read more
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Why Consider Zyrtec Generic Alternatives?
- Same active ingredient: Adult Zyrtec tablets and the generic products compared here use cetirizine HCl 10 mg.
- Lower-cost options: Generic cetirizine can provide a lower-cost alternative to the brand-name product.
- Different package sizes: Choose from smaller bottles, larger bottles, and multi-packs depending on how frequently you use cetirizine.
- Multiple manufacturers: Perrigo/Padagis, Major, and GoodSense provide different sourcing and package options.
- Easy comparison: You can browse the complete assortment on our Cetirizine / Zyrtec category page.
Is Generic Zyrtec the Same as Zyrtec?
Generic Zyrtec contains the same active ingredient as brand-name Zyrtec: cetirizine hydrochloride. Adult tablet products commonly provide 10 mg per tablet.
Generic products may differ in inactive ingredients, tablet appearance, manufacturer, packaging, and price. If you have questions about a particular inactive ingredient or product formulation, check the individual product label before use.
What Does Cetirizine 10 mg Do?
Cetirizine is an antihistamine used for temporary relief of common allergy symptoms. Depending on the product labeling, these may include:
- Sneezing
- Runny nose
- Itchy or watery eyes
- Itching of the nose or throat
- Itching associated with hives
Always follow the directions and warnings on the specific product label.
Pros & Cons of Cetirizine (Zyrtec Generics)
✅ Pros
| ❌ Cons
|
Zyrtec vs Perrigo/Padagis vs Major vs GoodSense
| Option | Active Ingredient | Pack Size | Best For |
|---|---|---|---|
| Zyrtec® | Cetirizine HCl 10 mg | Varies | Shoppers who specifically prefer the brand name |
| Perrigo/Padagis Cetirizine | Cetirizine HCl 10 mg | 300 tablets | Best overall value |
| Perrigo/Padagis 2-Pack | Cetirizine HCl 10 mg | 600 tablets | Largest supply / bulk shoppers |
| Major Cetirizine | Cetirizine HCl 10 mg | 45 tablets | Smaller everyday bottle |
| Major Cetirizine 2-Pack | Cetirizine HCl 10 mg | 90 tablets total | Middle-ground supply |
| GoodSense Cetirizine | Cetirizine HCl 10 mg | 90 tablets | Clearance while supplies last |
Which Zyrtec Generic Alternative Should You Choose?
The best choice depends mostly on how much cetirizine you want to buy at once.
- Best overall value: Perrigo/Padagis Cetirizine 300 Tablets
- Best bulk option: Perrigo/Padagis 600-Tablet 2-Pack
- Best smaller-count option: Major Cetirizine 45 Tablets
- Need about 90 tablets: Major Cetirizine 45-Tablet 2-Pack
- GoodSense shopper: Remaining GoodSense products are available while clearance inventory lasts.
To see the complete current assortment in one place, visit the Cetirizine / Generic Zyrtec Collection.
How Does Zyrtec Compare With Claritin?
Zyrtec uses cetirizine, while Claritin uses loratadine. They are different antihistamines and should not be treated as interchangeable simply because both are commonly used for allergy symptoms.
For a side-by-side comparison, read our Claritin vs Zyrtec Guide.
Related Zyrtec and Cetirizine Guides
- Claritin vs Zyrtec — Compare loratadine and cetirizine.
- Equate vs Perrigo Cetirizine — Compare retailer-brand and manufacturer-label cetirizine.
- Shop Cetirizine / Generic Zyrtec — Browse all currently available products.
Perrigo Cetirizine Hydrochloride 10 mg - 300 Tablets | Zyrtec
$17.99
Cetirizine Hydrochloride 10 mg Tablets – 300 Count | Generic Zyrtec® by Perrigo 24-Hour Allergy Relief for Less Perrigo Cetirizine Hydrochloride 10 mg delivers the… read more
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Perrigo Cetirizine Hydrochloride 10 mg - 300 Tablets | Zyrtec (2 Pack)
$29.99
Cetirizine Hydrochloride 10 mg – 600 Tablets (2 Pack) | Generic Zyrtec® by Padagis / Perrigo Stock Up & Save: Bulk Allergy Relief + Free… read more
View Product
GoodSense All Day Allergy Cetirizine 10 mg - 90 Tablets | Compare to Zyrtec
$5.99
GoodSense All Day Allergy Cetirizine 10 mg – 90 Tablets | Compare to Zyrtec® 24-Hour Relief for Indoor & Outdoor Allergies GoodSense® All Day Allergy… read more
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GoodSense All Day Allergy Cetirizine 10 mg - 90 Tablets | Compare to Zyrtec (2 Pack)
$9.99
GoodSense All Day Allergy Cetirizine 10 mg – 90 Tablets (2 Pack) | Compare to Zyrtec® Stock Up & Save: 6-Month Supply of Allergy Relief… read more
View Product
GoodSense Children's All Day Allergy Cetirizine 1 mg / mL - 4 fl oz | Compare to Children's Zyrtec
$7.99
GoodSense Children's All Day Allergy Cetirizine 1 mg / mL – 4 fl oz | Compare to Children’s Zyrtec - Bubble Gum Flavor GoodSense Children’s… read more
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GoodSense Children's All Day Allergy Cetirizine 1 mg / mL - 4 fl oz | Compare to Children's Zyrtec (2 Pack)
$16.99
GoodSense Children's All Day Allergy Cetirizine 1 mg / mL – 4 fl oz (2 Pack) | Compare to Children’s Zyrtec - Bubble Gum Flavor… read more
View Product
About Xeteor
Xeteor.com, founded in Las Vegas in 2018, is a trusted online store and healthcare product guide specializing in generic over-the-counter medicines, store-brand alternatives, blood glucose test strips, diabetic testing supplies, vitamins, and healthcare essentials.
We help shoppers find the right product when a brand name is too expensive, a store-brand label is confusing, insurance is not being used, or the product they usually buy is out of stock. For OTC products, our approach compares active ingredients, strengths, dosage forms, package sizes, manufacturers, pricing, availability, and fulfillment options. For diabetic testing supplies, we help customers compare meter compatibility, test strip type, expiration dating, package count, price per strip, and out-of-pocket value.
Our product analysis is led by Joe, the Head Xeteorologist, whose Joe’s Translation insights explain generic OTC products and diabetes supply choices in plain English.
We are the creators of the Xeteor Rx Quality Ladder and the Premium vs. Value Generic Drugs framework. These guides help explain how generic OTC products differ by manufacturer, labeler, sourcing model, supply reliability, and delivered value.
Our OTC generic portfolio includes:
- Tier 1 Premium Generics: GoodSense and Foster & Thrive.
- Tier 2 Standard Generics: Geri-Care, Reliable 1 Laboratories, Oncor Pharmaceuticals, and Health Star.
- Tier 3 Value Generics: Major Pharmaceuticals and Rugby Laboratories.
Many customers also come to Xeteor.com for affordable cash-pay diabetic testing supplies, especially blood glucose test strips, meters, lancets, control solution, and related diabetes supplies. Explore our Diabetes Management Guides, including guides for CareSens Test Strips, True Metrix Test Strips, and Original Bayer Contour Test Strips.
Xeteor is top-rated across major platforms including Trustpilot, Google, eBay, Amazon, and Walmart, with over 10,000 customer reviews across major platforms. Our goal is to combine clear product guidance, reliable products, and real human support by phone, email, and text.
For more plain-English comparisons, visit the Xeteor OTC & Diabetes Guides.
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Disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice. Always read and follow the product label. If you have a medical question, ask your doctor, pharmacist, or other qualified healthcare professional.
Important: Xeteor.com sells over-the-counter products, diabetic testing supplies, vitamins, and healthcare essentials. We do not sell, dispense, or fulfill prescription medications. OTC generic comparisons are based on factors such as active ingredient, strength, dosage form, package size, labeling, availability, and practical use case. Diabetes testing supplies must be compatible with the meter or device being used. Inactive ingredients, packaging, taste, texture, sourcing, expiration dating, and fulfillment path can vary.
Frequently Asked Questions
Is generic Zyrtec the same as brand-name Zyrtec?
Yes. Generic Zyrtec (Cetirizine HCl 10mg) is identical to the brand name. The FDA requires it to have the exact same active ingredient, strength, and effectiveness.
Is Perrigo Cetirizine discontinued?
No. Perrigo is the world's largest manufacturer of store-brand generics, and their Cetirizine (the generic for Zyrtec) is still in full production. We stock it as our "Premium" pick, GoodSense and under Perrigo's Padagis brand.
Who makes store brand Zyrtec (like Equate)?
Most store-brand Cetirizine (including Walmart's Equate and our "Premium" pick, GoodSense) is manufactured by Perrigo. They are the trusted leader in generic OTC production.
Why do some Zyrtec generics cost more than others?
This is our "Premium vs. Value" philosophy. "Premium" generics (like GoodSense by Perrigo) have retail-friendly packaging. "Value" generics (like Major or Rugby) use a simpler box to offer the lowest possible price. The medicine inside is identical.
What if cetirizine makes me drowsy?
Drowsiness is uncommon but possible. If you’re sensitive to it, consider a less-sedating antihistamine such as loratadine (Claritin). Always follow label directions or consult a healthcare professional.
What if Zyrtec (cetirizine) makes me drowsy?
Drowsiness is a common side effect of Zyrtec. Claritin (Loratadine) is a different, non-drowsy active ingredient that might be a better choice. You can learn which is right for you in our expert guide, "Zyrtec vs. Claritin."
