Colace Generic Alternatives: The Complete Guide to Docusate Sodium
Table of Contents
- What is Docusate Sodium and How Does It Work?
- Colace 2-in-1 vs. Standard Colace
- Quick Comparison: Brand vs. Generic Colace
- Pros & Cons of Switching to a Colace Generic Alternative
- Choosing the Right Generic Colace: Price Comparisons
- Why Xeteor is the Best Place to Buy Colace Generic Alternatives
- Side Effects and When to See a Doctor
- Colace Generic Alternatives: Further Reading & Comparisons
- Explore Our Complete Digestive Health Guides
- About Xeteor
- FAQs
When it comes to gentle constipation relief, exploring Colace generic alternatives is the key to getting the same effective relief while saving a significant amount of money. The active ingredient in Colace is Docusate Sodium, a safe and effective stool softener available from trusted generic brands.
This guide is your definitive resource for navigating the choices. As the #1 guide to Docusate Sodium, this pillar is part of our comprehensive Digestive Health Hub and will walk you through everything you need to know about choosing the best generic Colace for your needs.
What is Docusate Sodium and How Does It Work?
Docusate Sodium is the active ingredient in Colace and all its generic versions. It is a stool softener, not a laxative. It works by allowing more water and fats to mix into the stool, making it softer and therefore easier to pass. This makes Docusate Sodium an excellent choice for individuals who need to avoid straining during bowel movements, such as after surgery, after childbirth, or for those with hemorrhoids. It typically takes 12 to 72 hours to see an effect.
Colace 2-in-1 vs. Standard Colace

It's important to distinguish between standard Colace and Colace 2-in-1. While standard Colace only contains the stool softener Docusate Sodium, Colace 2-in-1 is a combination medication. It contains a smaller dose of Docusate Sodium (50 mg) plus a stimulant laxative called Sennosides (8.6 mg). This combination both softens the stool and stimulates the bowels to move, similar to Dulcolax.
Quick Comparison: Brand vs. Generic Colace
| Feature | Colace (Brand) | Generic (Docusate Sodium) |
|---|---|---|
| Active Ingredient | Docusate Sodium | Docusate Sodium |
| Effectiveness | Clinically proven stool softener | Medically identical and FDA-approved |
| Primary Use | Preventing straining, gentle relief | Preventing straining, gentle relief |
| Average Cost | Higher | Significantly Lower |
Pros & Cons of Switching to a Colace Generic Alternative
Switching from a brand you know can be stressful. Here’s a quick summary of the pros and cons of moving to a Colace generic alternative, Docusate Sodium.
✅ Pros
- Non-Habit Forming: Docusate Sodium is safe for long-term regular use and will not cause physical dependency, unlike stimulant laxatives.
- Gentle Mechanism: Works naturally by drawing water into the stool, preventing straining and making passage easier.
- Doctor Recommended: Stool softeners are often the first-line defense recommended by doctors for preventing constipation.
- Trusted Quality: All generics are FDA-approved to meet the same strict standards for safety and effectiveness.
❌ Cons
- Slow Onset: Relief may take 1 to 3 days to fully kick in. It is not designed for immediate, acute relief.
- Not a Stimulant: It does not make you "go." It only makes stool easier to pass, meaning it may be insufficient for severe constipation.
- Must Stay Hydrated: Works best when paired with plenty of water.
Choosing the Right Generic Colace: Price Comparisons
When selecting a Docusate Sodium product, the biggest advantage is cost savings. Trusted generic manufacturers like Major Pharmaceuticals and Rugby Laboratories offer the same product at a fraction of the brand-name price. It's also helpful to understand that not all generics are the same; learn more in our guide to Premium vs. Value Generic Drugs.
Colace Regular Strength vs. Generic Docusate Sodium 100 mg
| Product | Unit | Price | Price / Unit |
|---|---|---|---|
| Colace Regular Strength | 100 | $20.56 | $0.21 |
| Major Docusate Sodium 100 mg | 100 | $5.99 | $0.06 |
| Major Docusate Sodium 100 mg | 1000 | $24.99 | $0.02 |
Colace Extra Strength vs. Generic Docusate Sodium 250 mg
| Product | Unit | Price | Price / Unit |
|---|---|---|---|
| Colace Extra Strength | NA | NA | NA |
| Major Docusate Sodium 250 mg | 100 | $8.99 | $0.09 |
| Major Docusate Sodium 250 mg | 1000 | $39.99 | $0.04 |
Colace 2-in-1 vs. Generic Alternative
| Product | Unit | Price | Price / Unit |
|---|---|---|---|
| Colace 2-In-1 | 60 | $24.18 | $0.40 |
| Rugby 2-In-1 Laxative & Stool Softener | 100 | $6.99 | $0.07 |
| Rugby 2-In-1 Laxative & Stool Softener | 1000 | $22.99 | $0.02 |
Why Xeteor is the Best Place to Buy Colace Generic Alternatives
When searching for a daily health solution, trust and transparency are essential. Unlike anonymous third-party sellers on large marketplaces like Amazon and Walmart, Xeteor provides a trusted, direct, and reliable experience.
| Feature | xeteor.com | Amazon | Walmart |
|---|---|---|---|
| Authentic generics & test strips | ✅ GoodSense, Rugby Laboratories, Major Pharmaceuticals, Foster & Thrive, Oncor Pharmaceuticals; CareSens, Ascensia | ❌ 3rd-party sellers | ❌ Limited availability |
| Guaranteed Freshness | ✅ Expiration dates clearly listed | ❌ Expiration dates are unknown | ❌ Expiration dates are unknown |
| 100-day return policy | ✅ Free Return Shipping | ❌ 30 days | ❌ 30 days |
| Call us directly | ✅ 1-833-787-4777 • Real support | ❌ No phone support | ❌ No phone support |
Side Effects and When to See a Doctor
While Docusate Sodium is generally safe, potential side effects can include diarrhea, stomach cramps, bloating, and gas. It is crucial to seek medical attention if your constipation lasts for more than a week or is accompanied by other symptoms like rectal bleeding or severe abdominal pain. Always consult your doctor before starting any new medication.
Colace Generic Alternatives: Further Reading & Comparisons
To see how a gentle stool softener like Colace compares to other types of laxatives, explore our detailed guides:
- Miralax vs. Colace: Can You Take Them Together?
- Colace vs. Dulcolax: Which One Should You Take?
- Miralax vs. Dulcolax vs. Colace: The Ultimate 3-Way Comparison
Explore Our Complete Digestive Health Guides
For a complete overview of all our resources, including guides on medications, natural remedies, and general symptoms, visit our central Digestive Health Resource Center.
Learn more about specific formulas and product types in our related pillar pages:
- Miralax Generic Alternatives: For understanding how osmotic laxatives provide relief from occasional constipation.
- Dulcolax Generic Alternatives: For fast-acting relief with a stimulant laxative.
- Phazyme Generic Alternatives: For breaking down gas bubbles and providing relief from bloating.
- Benefiber Generic Alternatives: For clear-mixing wheat dextrin fiber that supports digestive health and regularity.
- Citrucel Generic Alternatives: For daily fiber support to maintain gut regularity.
- Metamucil Generic Alternatives: For bulk-forming psyllium husk fiber that supports cholesterol management and appetite control.
- Pepto-Bismol Generic Alternatives: For multi-symptom relief from upset stomach, heartburn, and indigestion.
Major Docusate Sodium 250 mg - 100 Softgels | Extra Strength Colace (2 Pack)
$15.99
Major Extra Strength Docusate Sodium 250 mg – 200 Softgels (2 Pack) | Compare to Colace® Stock up and save with this 2-pack of Major...… read more
Major Docusate Sodium 250 mg - 1000 Softgels | Extra Strength Colace
$48.99
Major Extra Strength Docusate Sodium 250 mg – 1000 Softgels | Compare to Colace® This bulk bottle of Major Docusate Sodium 250 mg contains 1000...… read more
About Xeteor
xeteor.com, founded in Las Vegas in 2018, is a trusted online guide and curated retailer for generic over-the-counter (OTC) medications. We operate like a family-owned business, thoughtfully selecting and offering a portfolio of brands that includes premium generics like GoodSense and Foster & Thrive, as well as trusted options such as Major Pharmaceuticals, Rugby Laboratories, Oncor Pharmaceuticals, and CareSens. Recognized as a Top Rated seller on Trustpilot, Google, eBay, Amazon, and Walmart, we're a trusted authority focused on building brand trust and earning consumer loyalty. Our mission is to empower you with reliable products and educational content, all backed by a U.S.-based team that offers real human support and secure, senior-preferred payment options.
Shipping
Orders placed by 3:00 PM PST, Monday–Friday, ship the same day. We offer free nationwide shipping on orders over $30 and on all qualifying Savings Packs. Average delivery time is 3.3 business days. View our full shipping policy here.
Payment Methods
We accept Visa, Mastercard, Discover, American Express, PayPal, Venmo, Google Pay, and Apple Pay.
Risk-Free Returns
All purchases are backed by our 100-day satisfaction guarantee. Not happy with your order? Return it for free. View our complete return policy here.
Need Help?
We’re here for you. Reach out via:
- Phone:1-833-787-4777 (M–F, 9 AM–5 PM PST)
- Email:[email protected]
- Text:702-659-7022
Visit our full Contact Us page for more options.
Disclaimer: This content is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider before starting any new supplement or treatment.
FAQs
Is Docusate Sodium the same as Colace?
Yes, Docusate Sodium is the active ingredient in the brand-name product Colace. Generic Docusate Sodium is medically identical to Colace, offering the same stool-softening relief at a more affordable price.
What is the difference between Colace and Colace 2-in-1?
Standard Colace is a stool softener only, containing just Docusate Sodium to make bowel movements more comfortable. Colace 2-in-1 is a combination product that contains both a stool softener (Docusate Sodium) and a stimulant laxative (Sennosides) to both soften stool and stimulate a bowel movement.
How does Colace work?
Colace is a stool softener, not a laxative. It works by allowing water and fats to mix into the stool, which increases moisture and softens it. This makes the stool easier to pass and helps to prevent straining.
How long does it take for Colace to work?
Colace works gradually and is not intended for immediate relief. It typically takes 12 to 72 hours (1 to 3 days) for its stool-softening effects to become noticeable.
Can you take Colace every day?
Yes, Colace (Docusate Sodium) is generally considered safe for daily or long-term use when taken as directed, as it is non-habit-forming. It is often recommended for chronic conditions or post-surgically to prevent straining.
How does Colace compare to other laxatives like Miralax or Dulcolax?
Colace is a gentle stool softener designed to prevent straining, while Miralax is a gentle osmotic laxative that produces a bowel movement over 1-3 days. Dulcolax is a much stronger, faster-acting stimulant laxative that causes intestinal contractions and is meant for short-term, urgent relief.